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Member Forum >> Diabetes / Pre-Diabetes Forum >> Jardiance Trial with type 2 diabetics showed a 38 percent reduction in CV death
 Jardiance Trial with type 2 diabetics showed a 38 percent reduction in CV death
searcher7

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Posted: 2/2/2017 12:50:33 AM
Edited: 2/2/2017 12:53:06 AM (1)
 
Boehringer Ingelheim and Eli Lilly and Company’s Jardiance® (empagliflozin) significantly reduced the risk of the combined endpoint of cardiovascular (CV) death, non-fatal heart attack or non-fatal stroke by 14 percent when added to standard of care, in patients with type 2 diabetes (T2D) at high risk of CV events. There was a 38 percent reduction in CV death, with no significant difference in the risk of non-fatal heart attack or non-fatal stroke.

In addition, treatment with Jardiance resulted in a lower risk of all-cause mortality (32 percent reduction) and hospitalization for heart failure (35 percent reduction).The effect of Jardiance in this trial was observed on top of standard of care. This means the benefit was seen over and above other treatments patients were already receiving for diabetes and/or cardiovascular disease (such as blood pressure and cholesterol lowering-medications)

 Jardiance is an oral, once daily, highly selective sodium glucose co-transporter 2 (SGLT2) inhibitor. Jardiance works by blocking the reabsorption of glucose (blood sugar) by the kidney, leading to urinary glucose excretion, and lowering blood glucose levels in people with type 2 diabetes. SGLT2 inhibition targets glucose directly and works independently of β-cell function and the insulin pathway.

Jardiance is not for people with type 1 diabetes or for people with diabetic ketoacidosis (increased ketones in the blood or urine).

Wouldn't it be better to eat a low carb,low sugar,low starch,no grains diet to keep one's blood glucose level down instead of trying medication?
https://www.boehringer-ingelheim.com/press-release/jardiance-only-diabetes-medication-show-significant-reduction-both-cardiovascular-risk

 



Tags: ,Blood Glucose,Low Carb High Fat Indirectly Wheat Free

Bob Niland

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Posted: 2/2/2017 7:32:51 AM
Edited: 2/2/2017 8:10:32 AM (1)
 
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Posted: 2/20/2017 1:51:48 PM
 
We can assume that insulin levels were lower as well - but for some reason they didn't measure that?



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Leesa

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Posted: 8/26/2019 8:27:54 AM
Edited: 8/26/2019 9:40:33 AM (1)
 
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Bob Niland

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Posted: 8/26/2019 9:31:28 AM
 
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Posted: 8/26/2019 10:04:32 AM
 
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Posted: 8/26/2019 4:34:07 PM
 
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Posted: 8/27/2019 10:09:52 AM
 
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Posted: 8/27/2019 3:48:50 PM
 
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