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Member Forum >> Bowel Flora and Digestive Health >> What is a healthy gut microbiome composition?
 What is a healthy gut microbiome composition?
pamoja

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Posted: 12/22/2019 6:22:43 PM
 
Googled and found this recent paper: https://www.mdpi.com/2076-2607/7/1/14/pdf

Its composition still seems not really defined. Beyond low diversity, how is one to define dysbiosis?

4. Conclusions

Each healthy human is provided with unique gut microbiota. Core native microbiota are shaped
in early life (4–36 months) by gut maturation developing from enterotype, birth gestational age, type of delivery, methods of milk feeding, weaning period, lifestyle, and dietary and cultural habits. After a child reaches 2–3 years old, a relative stability in gut microbiota composition has been demonstrated. Richness and diversity of gut microbiota shaped in early life characterize a healthy gut microbiota composition. However, this optimal healthy gut microbiota composition is different for each individual.

Throughout life, the richer and more diverse the microbiota, the better they will withstand
external threats. Indeed, gut microbiota represent a changing ecosystem that is severely tested by many factors such as unbalanced diet, stress, antibiotic use, or diseases. A healthy host–microorganism balance must be respected in order to optimally perform metabolic and immune functions and prevent disease development. Indeed, disturbances to the delicate host–microbe relationship may disrupt the development of the immune system, which may in turn result in diseases [113]. Although the role of gut microbiota is still poorly understood, the close association between gut microbiota dysbiosis and intestinal and extra-intestinal disorders has been demonstrated. This is the reason why dysbiosis can be considered as a biomarker of such disorders and that the study of gut microbiota balances shall be one of the priorities for future therapies to prevent and treat diseases.



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Posted: 12/22/2019 11:51:21 PM
 
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Posted: 1/6/2020 8:06:59 PM
 
Pamoja is it possible to get the Thryve sequence for like $99 with a coupon code? They want $149 right now without code.
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