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Member Forum >> Vitamin D >> VDR Mutations & Vitamin D 25 Hydroxy, Parathyroid Hormone, Calcitriol
 VDR Mutations & Vitamin D 25 Hydroxy, Parathyroid Hormone, Calcitriol
JennVsDiabesity

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Posted: 1/2/2020 11:14:08 AM
Edited: 1/2/2020 11:21:57 AM (5)
 
What do you think about this video from Chris Masterjohn, PHD?

https://www.youtube.com/watch?v=Ziwh7yNsxno

I have the VDR Taq homozygous (+/+) mutation.  I have no other VDR mutations.  (Got this info from raw 23AndMe genetic data run through Genetic Genie to show me my Methylation profile.)

He says Vit D 25 Hydroxy level of say 30-40 ng/mL could be sufficient if you don’t have VDR mutations, but you might need 60-70 ng/mL if you have a VDR mutation. 

He discusses how one can test for Parathyroid hormone (PTH) as well as Calcitriol to determine if you have enough vitamin D 25 hydroxy.  Like if Calcitriol and Vit d 25 hydroxy are in the normal range but you still have HIGH parathyroid hormone, it could be due to the VDR mutation, and would benefit with more Vit D supplementation.

Just wondering if it would be useful to test the PTH and Calcitriol as well, since I have this homozygous VDR Taq mutation.  
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hopscotch

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Posted: 1/2/2020 11:41:55 AM
 
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JennVsDiabesity

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Posted: 1/2/2020 1:44:17 PM
 
Yeah it’s just that I have the homozygous mutation.. would feel better if it was heterozygous or no mutation :)
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Posted: 1/2/2020 3:00:49 PM
 
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