Originally posted by Dr. Davis on 2016-04-01
on the Wheat Belly Blog, sourced from and currently found at: Infinite Health Blog.
PCM forum Index of WB Blog articles.

ZERO TOLERANCE for hypoglycemia

Wheat elimination starts you powerfully on the path to reversing diabetes. We’ve seen it many times and it continues to develop in people who kiss their bagels, pretzels, and processed foods booby-trapped with wheat and grains goodbye.

But, as diabetics become less diabetic–a process that can occur VERY quickly, often within days of removing all wheat and grain products from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started administering insulin or blood sugar-reducing drugs–it would result in a mess.)

Unfortunately, you cannot always rely on your doctor. Most physicians are unschooled in how to cure diabetes and therefore how to manage the hypoglycemia that may develop on your way to cure. (They are very good at CAUSING diabetes, however, prescribing diets like “An 1800-calorie American Diabetes Association Diet,” a typical dietary order in the hospital that RAISES blood sugar.) It is nonetheless important to at least discuss your questions with your doctor. (If you encounter resistance, get a new doctor, preferably one in functional medicine who is more apt to understand nutrition and biochemistry.)

So I reprint a section I wrote for the Wheat Belly Cookbook that details some of the important issues to be aware of if you are diabetic on insulin or diabetes drugs and remove wheat from your diet:

“There is not a shred of evidence that sugar, per se, has anything to do with getting diabetes.”
Richard Kahn, PhD
Recently retired Chief Scientific & Medical Officer
American Diabetes Association

Dr. Kahn’s comment echoes conventional thinking on diabetes: Eat all the grains and candy you want . . . just be sure to talk to your doctor about diabetes medications.

If you eat foods that increase blood sugar, it increases your need for diabetes medications. If you reduce or eliminate foods that increase blood sugar, then it decreases your need for diabetes medications. The equation for most people with adult, or type 2, diabetes, is really that simple.

But several precautions are necessary if you are diabetic and are taking certain diabetes drugs. The potential danger is hypoglycemia, low blood sugars (e.g., less than 70 mg/dl) . . . as well as the uninformed objections of many doctors who have come to believe that diabetes is incurable, irreversible, and a diagnosis for life.

Some medications, such as metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and acarbose (Precose), rarely if ever result in hypoglycemia when taken by themselves. They are effective for preventing blood sugar rises, but tend to not generate blood sugar lows.

However, other medications, especially glyburide (DiaBeta, Micronase), glipizide (Glucotrol), glimepiride (Amaryl), and various insulin preparations can cause severe and dangerous hypoglycemia if taken while reducing or eliminating wheat and carbohydrates. For this reason, many people eliminate these oral drugs or slash insulin doses by 50% at the start, even if it means some temporary increase in blood sugars. The key is to avoid hypoglycemia as you consume less food that increases blood sugar, even if it means higher near-term blood sugars.

Other medications, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), exenatide (Byetta) and liraglutide (Victoza) usually do not result in hypoglycemia but occasionally can, especially if taken in combination with other diabetes drugs.

Because of the complexity of these responses, you should ideally work with a healthcare provider adept at navigating these issues as you become less and less diabetic. Problem: Most doctors and diabetes educators have no idea whatsoever how to do this, as they will tell you that, once you have diabetes, you will always have it and trying to get rid of it is fruitless and foolhardy (to the appreciative applause of the diabetes drug industry). So don’t be surprised if you are left on your own. At the very least, you want to check to see if your doctor will work with you and, if not, at least try and find another who will. Also, frequent monitoring of blood sugars is essential. I tell my patients on the path to becoming non-diabetic that high blood sugars (though maintained below 200 mg/dl) are preferable to low blood sugars (below 100 mg/dl) in this transition period. If, for instance, you are obtaining blood sugars in the morning (fasting) of 100 mg/dl, it is time to further reduce or eliminate a medication, such as glipizide or Lantus insulin taken at bedtime.

Any diabetic who wants to better understand the details of becoming non-diabetic would also benefit from knowing about the resources of Dr. Richard Bernstein, author of The Diabetes Solution. More information can be found at www.diabetes-book.com. The critical issue here is to understand that many people with diabetes have been told that they have an incurable condition for a lifetime and that a diet rich in “healthy whole grains” is essential—-advice that ensures you remain diabetic. Do the opposite─-eliminate “healthy whole grains,” especially the most dangerous grain of all, wheat─-and limit other carbohydrates, including non-wheat grains like millet, corn, and oats, and diabetes unwinds itself with reduced fasting blood sugars and HbA1c in the majority.

More recently, the American Diabetes Association’s Chief Scientific & Medical Officer, Dr. Richard Kahn, added, “Diabetes prevention is a waste of resources.” Why, think of all the money that could instead go to pharmaceutical research and marketing!