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Member Forum >> Digestive Health Forum >> Parkinson's Gut Origin: Path to Brain Evident in Data
 Parkinson's Gut Origin: Path to Brain Evident in Data
Bob Niland

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Posted: 7/7/2015 8:48:32 AM
Edited: 7/7/2015 8:49:47 AM (1)
 
Interpretation: Full truncal vagotomy is associated with a decreased risk for subsequent PD, suggesting that the vagal nerve may be critically involved in the pathogenesis of PD.

AoN: Vagotomy and subsequent risk of Parkinson's disease (pay-walled)
NN: Parkinson’s May Begin in Gut and Spread to the Brain Via the Vagus Nerve (free press story)

I'll bet this caused Dr. Perlmutter to set down his coffee this morning.

The next question, of course, is what agent in the gut is at cause, and what conditions give rise to that. I won't be the least bit surprised if people attending to gut health are also at lower risk, but there's likely no unconfounded epidemiological data to study on that. I also won't be surprised if the root cause is strongly associated with the usual list of gut antagonists, with the gluten-bearing grains being at the top.
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BirdmanSam

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Posted: 7/7/2015 3:18:37 PM
 
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Bob Niland

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Posted: 7/7/2015 3:50:53 PM
 
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Dr. Davis

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Posted: 7/8/2015 10:56:21 AM
 
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ptheut

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Posted: 7/8/2015 3:55:11 PM
 
back in the day MD's would cut the vegas nerve when they operated on ulcers.  wonder how the patients did with regard to PD?


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Bob Niland

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Posted: 7/8/2015 4:20:46 PM
 
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Bob Niland

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Posted: 11/1/2018 7:51:21 AM
 
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Dr. Davis

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Posted: 11/1/2018 5:28:55 PM
 
Yes, a very curious and confusing finding. 


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Bob Niland

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Posted: 11/10/2018 10:34:26 AM
 
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Bob Niland

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Posted: 12/9/2018 10:22:40 AM
 
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Dr. Davis

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Posted: 12/9/2018 3:53:29 PM
Edited: 12/9/2018 3:54:02 PM (1)
 
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TQ

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Posted: 3/22/2021 2:01:14 PM
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Venkat S

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Posted: 3/22/2021 11:47:17 PM
 
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Rippey

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Posted: 9/22/2022 9:54:09 PM
 
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Bob Niland

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Posted: 9/22/2022 10:26:04 PM
 
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Posted: 9/22/2022 10:45:38 PM
 
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Posted: 9/23/2022 12:52:55 PM
 
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Posted: 9/24/2022 4:41:41 AM
 
https://neurosciencenews.com/alzheimers-gum-disease-21475/


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