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Member Forum >> General Discussion >> Important SNPs -- Share your’s / what you think is important.
 Important SNPs -- Share your’s / what you think is important.
JennVsDiabesity

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Posted: 1/3/2020 11:33:24 AM
Edited: 1/3/2020 12:24:28 PM (5)
 
I’ve been geeking out on my 23AndMe Raw Genetic Data using Promethease along with "Genetic Genie" for Methylation Profile.

Just wondering if people would share which SNPs are the most important to look at?

I know the ApoE and Methylation Profile (MTHFR, MTRR, VDR, COM, etc..) are both important.  Just recently learned about the importance of Factor V Leiden (clot risk) and that is in the 23AndMe raw data as well.

Just today I learned about GSTP1, with respect to Vitamin E supplementation.

Any other significant ones people would like to share here?

------

Of what I mentioned above here are my results:

ApoE e2/e4 (yuck I am pretty carb intolerant but already knew that.. also my poor arteries? CAC soon.)

From Genetic Genie using raw 23andme data:
MTHFR -- not a single mutation (all -/-). (Folic acid in multivitamin is fine for me I presume)
MTRR -- only one mutation:  MTRR A66G (+/+)  So I supplement with 500 mcg Methyl B12 lozenge now.
VDR Taq (+/+): so I am gonna make sure I am at 70 ng/mL Vit D 25 Hydroxy for sure now.

Factor V Leiden rs6025. I’m (G;G) / (-/-) so not at high risk for DVT or clotting.  (Can you believe this genetic DNA test is $249 at walkinlab.com?  I love 23andMe raw data!)

GSTP1: rs1695. I’m (A;A) / (-/-) so I guess I don’t need Vitamin E supplementation? (Thanks VenSub/Malcom)

----

Look forward to more SNPs!  Please share your SNPs and what you think is important beyond these.  I have no idea what to look for in Promethease because I am not smart enough to know what is useful!
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Bob Niland

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Posted: 1/3/2020 11:49:30 AM
Edited: 1/3/2020 11:50:21 AM (1)
 
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JennVsDiabesity

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Posted: 1/3/2020 12:12:41 PM
Edited: 1/3/2020 12:18:24 PM (4)
 
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Toby Lime

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Posted: 1/3/2020 1:12:51 PM
 
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JennVsDiabesity

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Posted: 1/3/2020 1:22:14 PM
Edited: 1/3/2020 1:25:14 PM (2)
 
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Toby Lime

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Posted: 1/3/2020 1:28:54 PM
 
What are the tweaks that you’re using Jenn?


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JennVsDiabesity

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Posted: 1/3/2020 2:34:39 PM
Edited: 1/3/2020 2:42:33 PM (1)
 
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Toby Lime

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Posted: 1/3/2020 5:29:32 PM
Edited: 1/3/2020 5:35:51 PM (1)
 
Good for you!

I have a similar strategy to yours but I’m not losing weight. I probably should go and see somebody or not... I don’t know what is wrong with my body???


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TrueFaith

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Posted: 1/4/2020 7:55:16 AM
 
I think I have the MTHFKR gene. 
At least that’s what the guy I accidentally cut off in traffic last week called me.
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Rodney D

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Posted: 1/4/2020 9:08:44 AM
 
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Toby Lime

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Posted: 1/5/2020 3:36:18 PM
 
... you guys are hilarious! I like this a lot.
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Toby Lime

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Posted: 1/5/2020 3:39:17 PM
Edited: 1/5/2020 3:49:17 PM (1)
 


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JennVsDiabesity

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Posted: 1/13/2020 9:28:40 AM
Edited: 1/13/2020 10:13:39 AM (4)
 
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JannyLite

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Posted: 1/19/2020 11:30:04 PM
Edited: 1/19/2020 11:30:30 PM (1)
 
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JannyLite

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Posted: 3/25/2020 9:02:39 PM
 
Toby Lime: Did you ever post all your data to the Forum for Dr. Davis, Bob, et al’s review? Perhaps they may notice something. I’m always surprised how they find a tweak that puts everything in perspective and off ya go.

Jan
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