February 2010
The Confidential Newsletter of the Track Your Plaque Program 
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Can fish oil keep you young?

Just when you thought it couldn't get any better, another compelling reason for knowing your Omega-3 Blood Index and optimizing your fish oil dose has been uncovered.

A new study among patients with coronary artery disease (CAD) has discovered an association between fish oil and the rate at which telomeres shorten (January 20, 2010 issue of the Journal of the American Medical Association). Telomeres are the stretches of DNA that are thought to be the body’s way of keeping track of aging: The older you are, the more your telomeres are shortened.

The rate of telomere shortening is thought to determine the number of times a cell can replicate, thus limiting the life of a cell. This shortening of telomeres has been shown to independently predict morbidity and mortality in patients with CAD.

According to lead researcher in the study, Dr. Farzaneh-Far, "This suggests the existence of a novel mechanism for why omega-3 fatty acids are effective in this patient population—an area that has not been well worked out previously; it suggests they could be acting through telomeres . . . It's also the first study that shows that a dietary factor may be able to slow down telomere shortening . . . This is yet another reason for cardiologists to try to convince their patients to take either a fish-oil supplement or eat regular fatty-fish meals."

The bottom line of this observational study is that participants with the lowest levels of omega-3 fatty acids had the fastest rate of telomere shortening. Compared with those with the highest omega-3 blood levels, participants with the lowest omega-3 blood levels had 60% greater telomere shortening. To perform this analysis, Dr. Farzaneh-Far and his team used what they called "a relatively new blood test" called the Omega-3 Index test. The test cut-offs were 2.3% for those with the fastest (worst) telomere shortening and 7.3% for the slowest (best) shortening.

Dr. Davis and Track Your Plaque are once again ahead of the curve in bringing the Omega-3 Index test to its Members for some months now. Track Your Plaque also provided a discussion on Omega-3 Index testing in its October 2009 newsletter. What was the blood level discussed? 7.3% and higher!

Now for the REAL bottom-line: Just like Vitamin D, it doesn't matter how much you take, it matters how much omega-3 fatty acids get into your blood. With vitamin D, for instance, some people need 1000 units per day, others need 20,000 units per day, most need something in between. So it goes with omega-3 fatty acids. In fact, you may not even know, in many cases, whether the preparation you take even contains the stated quantity. Unless you test your blood level, you have no idea if you are receiving optimal treatment.

Dr. Farzaneh-Far concludes: "From the telomere point of view, this is the first study to show an effect of a dietary factor, that this may be able to slow down telomere shortening . . . The idea is that the omega-3 index, the percentage of [omega-3] fatty acids in the blood, could be measured and that low levels would predict worse outcomes. So the omega-3 index might be useful for risk stratification in the future."

Call your doctor, get the test. If your doctor says, "No!" then test yourself to get a baseline reading and decide whether it might be a good idea to get OPTIMAL treatment.

 

What's hot on the TYP website?

Track Your Plaque Members can rightly boast of the highest "Heart IQ" as the most well-educated and experienced practitioners of heart disease prevention and reversal.  Here is a list of last month's Top Ten Topics -  new resources and Member Forum topics that Track Your Plaque Members found the most interesting and useful in their personal programs to prevent and reverse heart disease.  Find out what you may have been missing!

Postprandial Lipoproteins--The Storm After the Quiet: This new TYP Special report introduced opened the shutters revealing a raging storm in your body!

Postprandial Lipoproteins: Part 2 - The triglyceride tolerance test: Part 2 of this series introduced a proprietary TYP method to test your post-prandial triglyceride risk.

Discussion: Postprandial Lipoproteins--The Storm After the Quiet: And, of course, the new report led to lengthy discussion in the Member Forum.

TYP Health Eating: Our newest forum moderated by nutritionist and dietitian, Margaret Pfeiffer, MS, RD, CLS. Margaret has 15 years of experience counseling patients on heart disease prevention and is as a practicing Cardiac Nutritionist and Clinical Lipid Specialist.

Ongoing Blood Sugar Experiment - Some Results: TYP Member "Adventure9" takes us all on an adventure sharing detailed personal analysis of blood sugar effects of different foods.

Tracking Plaque....What can we really learn about plaque: TYP Member "jegesq" ignites a lively and informative discussion on heart scans, their meaning, and their use.

Saturated Fat Not Linked to Heart Disease: TYP Member "gobears" shares a new study on saturated fat that may change the way you think about eating.

Low-carb: Postprandial responses: Many people replace carbs with fats on low-carb diets.  The Members discuss how fats should be incorporated and what limits to use.

Can these numbers be reversed without statins?: Few people WANT to take statins.  But, can the tough cases be solved without them?

If you do need it, how much and what kind of statin should you take?: In an in depth follow-up TYP Members reveal their research and experiences using statins to lower LDL and what works.


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