December 2006 Copyright 2006, Track Your Plaque, LLC 

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Track Your Plaque shows how to use CT heart scans as the 1st step in a proven program to slow, stop, even REVERSE heart disease!

In this issue:

Hello, everybody!

If you haven’t joined me on my Heart Scan Blog, you should! In the last month, I’ve discussed topics like:

  • Heart disease "reversal" by stress test—An interesting case of heart disease “reversal” by stress testing (reprinted below).
  • Annual physical—The folly of the annual physical examination. You can pass only to fail the test of life!
  • A curious case of regression—The more experience accumulates in coronary disease reversal, the more fascinating lessons we learn. A woman drops her heart scan score by more than 20%―contrary to our expectations.
  • Heart scan score drops like a stone—23% drop in heart scan score!
  • "You don't have a uterus. You don't need progesterone"—The mis-guided advice of many conventionally-thinking gynecologists. “If you’re not sick, why bother?”
  • Take a niacin "vacation"—The longer you take niacin to correct lipoprotein patterns, the more a break from your niacin should be considered.

Go to www.trackyourplaque.com and click on Blog with Cardiologist Dr. William Davis. You’re welcome to post your comments and participate in the conversation.

Track in health!

Dr. Davis

Another Track Your Plaque success story:
Diabetes is not a death sentence from heart disease!

Tim’s diabetes hit him like a truck. At age 62, Tim’s weight dropped unintentionally 25 lbs. over two months. Although he liked the weight loss, he felt awful: exhausted, even when he first got out of bed; lightheaded; and urinating large volumes. He was barely able to function in his job as CEO of a small manufacturing company.

Tim’s primary physician diagnosed diabetes and put him on two medications, one of which was Actos® (pioglitazone) . Within days, Tim felt normal again, though a good deal thinner. But his doctor warned him that the episode he suffered could have become very dangerous, sometimes even resulting in a condition called “hyperosmolar coma”, a state of profound dehydration so severe it results in coma.

Tim took the advice to heart. He got himself a heart scan to see if hidden heart disease was also lurking. His score: 318, in the 80th percentile compared to other men in his age group (approximately 3% annual risk for heart attack).

Tim’s primary physician put him on a statin cholesterol drug (Vytorin®). LDL cholesterol was reduced by the drug to a favorable level of 66 mg/dl, verified by a LDL particle number of 813 nmol/l (Track Your Plaque target <700 nmol/l). His lipoprotein analysis (NMR, Liposcience) on both Vytorin® and Actos® (an unusual diabetes agent in that it partially corrects lipoprotein patterns) also revealed:

• HDL 43 mg/dl, with only 3 mg/dl of effective large HDL
• Small LDL representing 80% of all LDL particles, a severe pattern.

Vitamin D supplementation increased 25-OH vitamin D3 from 22 ng/ml to 54 ng/ml.

We also counseled Tim on reducing processed carbohydrates, wheat products, and increasing reliance on lean proteins, especially raw nuts, and oat products to improve his profile, particularly small LDL.

One year later, Tim’s heart scan was repeated. His score: 244, a 23% reduction.

Dr. Davis: Last month, we profiled another Track Your Plaque participant who also had adult diabetes yet dropped his heart scan score. Tim is another diabetic who beat the odds.

Conventional medical wisdom is that diabetes represents a profound risk for heart disease. Rates of plaque growth of 50% per year are not uncommon when causes remain uncorrected. These two Track Your Plaque participants are examples of how this is not necessarily true if the proper steps are taken. Not only did they diminish risk, they reversed coronary atherosclerotic plaque―dramatically.

Tim’s case is somewhat more complicated in that he was taking a diabetes medication that may have influenced lipoprotein patterns. This is, of course, not a strategy that should be used by non-diabetics.

But the lesson learned from Tim’s case is that diabetes is not necessarily a death sentence from heart disease, as conventional medicine dictates. Tim’s substantial reduction in heart scan score will translate into a profound reduction in his risk for heart attack, as well as dramatically slashing likelihood of ever needing a heart procedure.

Calcium: “Hard” or “Soft” Plaque?

“My doctor said that heart scans are worthless because they only measure calcium. He says that calcium only tells you if there's hard plaque, and that hard plaque is stable. He says that calcium won't tell you anything about soft plaque, and soft plaque is what really that causes heart attack."

Is that true? Is calcium only a reflection of "hard" plaque? Is hard plaque also more stable, less prone to rupture and cause heart attack? Does calcium scoring provide only part of the picture?

Let’s go back to the original study that provided the basis for heart scans, peformed by heart scan pioneer, Dr. John Rumberger. In his now-famous study, Dr. Rumberger studied the coronary arteries of people who had died. He found that, by examining arteries cut into dozens of cross-sections, calcium comprised 20% of the volume of total plaque. This held true in men and women, young and old. This simple phenomenon led Dr. Rumberger to surmise that if calcium could be measured precisely, total coronary plaque volume could also be measured, since each cubic millimiter of calcium represented five (20%) cubic millimiters of plaque.

Calcium is therefore a means of measuring total plaque, both soft and hard. Within plaque, there may be areas that are soft (labeled "lipid pool" in the diagram). There are also areas made of calcium (shown in white arcs within the plaque). Even though this is just a graphic, it's representative of what is seen when we perform intracoronary ultrasound of a live human being's coronary artery. In other words, this cross section contains both "soft" (lipid pool) as well as "hard" (calcium) elements. Most atherosclerotic plaque, however, is a mixture of structural fibers, cholesterol crystals, cellular material, and debris.

Is the artery in the diagram "soft" or "hard"? It's both, of course. Artery compostion varies millimeter by millimeter, having more soft elements in one segment, more hard elements in another. The artery can also change over time in either direction. Thus, "soft" plaque may indeed be soft today, only to be "hard" in 6 months, and vice versa.

What the CT heart scan does is provide a gauge of total plaque, soft and hard, and it does so easily, safely, precisely. If your score increases, the lengthwise volume of total plaque has also grown. If your score decreases, the total amount of plaque has also decreased.
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Heart Disease Reversal by Stress Test?

(Reprinted from the December 4, 2006 Heart Scan Blog.)

Here's an interesting example of a 71-year old man who achieved "reversal" of an abnormality by a nuclear stress test.

This man underwent bypass surgery around 10 years ago, followed by two stents three years ago. A nuclear stress test in April, 2005 showed an area of poor blood flow in the front of the heart. On the images, normal blood flow is shown by the yellow/orange areas; poor or absent blood flow is shown by the blue/purple areas within the white outline.

Now, I can tell you that this man is no paragon of health. He's only accepted limited changes in his otherwise conventional program—in other words, someone who I wouln’t expect to achieve true reversal of his heart disease. (I didn't have him undergo any CT heart scans because of the difficulties in scoring someone who has undergone bypass surgery and stents, and because of limited motivation. True plaque reversal is for the motivated.) This patient did, however, accept adding fish oil and niacin to his program.

Nonetheless, stress testing can be helpful as a "safety check". Here's the follow-up stress test:

You'll notice that the blue/purple areas of poor blood flow have just about disappeared. This occurred without procedures.

Does this represent "reversal"? No, it does not. It does represent reversal of this phenomenon of poor flow. It does not represent reversal of the plaque lining the artery wall. That's because improvement of flow, as in this man, can be achieved with relatively easy efforts, e.g., statin drugs, blood pressure control, etc. True reversal or reduction of coronary plaque, however, is tougher.

If blood flow improves, who cares whether plaque shrinks? Does it still matter? It does.

That's because the "event" that gets us in trouble is not progressive reduction in blood flow, but "rupture" of a plaque. A reduction in plaque—genuine reversal of heart disease—is what dramatically slashes risk of plaque rupture and heart attack.

Interested in becoming a Track Your Plaque Member?

If you’re interested in finding out more about becoming a Member of Track Your Plaque, go to the Track Your Plaque Member Benefits page. See why more and more people are finding out that there are alternatives to the conventional answers (or lack of answers!) for heart disease.

Track Your Plaque Members: Watch for our upcoming Special Reports

Watch for our upcoming Special Reports on:

Fasting: Fast Track to Plaque Control
If you’re eager to gain profound control over the causes of coronary plaque, fasting can be an extremely fast and effective method. Fasting shouldn’t be viewed as a harsh punishment, but a positive, enlightening experience that can supercharge your success faster than almost any other strategy. Read our Special Report on when you can safely fast, when you should not, what to expect, and all the variations on how to do it.

Lipoprotein Checklists
People sometimes complain that specific efforts to correct lipid and lipoprotein patterns are often complex and confusing. We’ve assembled several checklists for quick reference in your efforts to gain control over your patterns.

5 Days of Heathful Recipes from author and world-renowned chef, Michel Nischan. Author of Taste: Pure and Simple, Nischan shares his secrets of how he transformed a NY French restaurant into the Heartbeat, a restaurant devoted to creating gourmet heart-healthy dishes.

Copyright 2006, Track Your Plaque