What if your lipoproteins are perfect?



Sandy is a 56-year old woman--fit, slender, physically active, with no bad habits. A retired teacher, she has time to devote to her health. She bikes several days per week, mountain bikes, walks, and takes fitness classes. In short, she's the picture of perfect health.

Her heart scan score was not terribly impressive: 41. However, at her age, this modest score placed her in the 77th percentile. This suggested a heart attack risk of around 2-3% per year.

So we measured Sandy's lipoproteins. They were shockingly normal. In fact, Sandy is among the very rare person with absolutely no small LDL particles. All other patterns were just as favorable, including an HDL in the 80s.

This may seem like good news, but I find it disturbing. People are often initially upset by seeing multiple abnormal lipoprotein patterns. But lipoprotein abnormalities are the tools that we use to gain control over coronary plaque.

So what do we do when there are no abnormalities?

There are several issues to consider:

1) Your heart scan score reflects the sum total of your life up until that point. What if you were 20 lbs heavier 10 years earlier and your lipoproteins were abnormal during that period? Or you smoked until age 45 and quit? As helpful as they are, lipoproteins and related patterns are only a snapshot in time, unlike the heart scan score.

2) You have a vitamin D deficiency. This is unusual as a sole cause of coronary plaque. Much more commonly, it is a co-conspirator.

3) The heart scan is wrong--highly unlikely. Heart scans are actually quite easy, straightforward tests. (The only time this tends to happen is when scoring that appears in the circumflex coronary artery is actually in the nearby mitral valve. This really occurs only when there's very minimal calcium in the valve.)

4) There's a yet unidentified source of risk. Probably very rare but conceivable. For instance, there's an emerging sense that phopholipid patterns may prove to be coronary risks. One clinically available measure that we've not found very useful is phospholipase A2, known by the proprietary name "PLAC" test. (See http://www.plactest.com for more information from the manufacturer/distributor of the test.) But there's probably lots of others that may prove useful in future.

How often does it happen that someone fails to show any identifiable source for their coronary plaque? I can count the number of instances on two fingers--very unusual. (Thank goodness!)

Sandy's case is therefore quite unique. How should we approach her coronary plaque? In this unusual circumstance, lacking a cause, we tend to introduce therapies that may regress plaque independent of any measurable lipoprotein parameters. But that's a whole new conversation.
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What's worse than sugar?

What's worse than sugar?

There are a number of ways to view the blood sugar-raising or insulin-provoking effect of foods.

One way is glycemic index (GI), simply a measure of how high blood sugar is raised by a standard quantity of a food compared to table sugar. Another is glycemic load (GL), a combination (multiplied) of glycemic index and carbohydrate content per serving.

Table sugar has a GI of 65, a GL of 65.

Obviously, table sugar is not good for you. The content of white table sugar in the American diet has exploded over the last 100 years, totaling over 150 lb per year for the average person. (Humans are not meant to consume any.)

What is the GI of Rice Krispies cereal, organic or not? GI = 82-- higher than table sugar. GL is 72, also higher than table sugar.

How about Corn Flakes? GI 81, GL 70--also both higher than sugar.

How about those rice cakes that many dieters will use to quell hunger? GI 78, GL 64.

How about Shredded Wheat cereal? GI 75, GL 62.

All of the above foods with GI's and GL's that match or exceed that of table sugar are made of wheat and cornstarch. Some, like Shredded Wheat cereal and rice cakes, don't even have any added sugar.

Stay clear of these foods if you have low HDL, high triglycerides, high blood sugar, or small LDL. Or, for that matter, if you are human.

Keep the eloquent words of New York University nutritionist, Marion Nestle, author of the book, Food Politics, in mind:

“Food companies—just like companies that sell cigarettes, pharmaceuticals, or any other commodity—routinely place the needs of stock holders over considerations of public health. Food companies will make and market any product that sells, regardless of its nutritional value or its effect on health. In this regard, food companies hardly differ from cigarette companies. They lobby Congress to eliminate regulations perceived as unfavorable; they press federal regulatory agencies not to enforce such regulations; and when they don’t like regulatory decisions, they file lawsuits. Like cigarette companies, food companies co-opt food and nutrition experts by supporting professional organizations and research, and they expand sales by marketing directly to children, members of minority groups, and people in develop countries—whether or not the products are likely to improve people’s diets.” ??

Comments (11) -

  • Peter Silverman

    9/16/2008 2:24:00 PM |

    What puzzles me is why the Japanese who eat their high glycemic diet (rice and more rice) have such low rates of heart disease and diabetes and live a lot longer than we do.

  • Jenny

    9/16/2008 2:26:00 PM |

    Dr. Davis,

    Be wary of the Glycemic Index. It has been promoted very heavily by the grain companies as a way of confusing the public that their products are healthy.

    The Glycemic Index values are established by testing foods in completely normal people. Anyone who has abnormal glucose tolerance (i.e. prediabetes) is likely to have a very different reaction to a supposedly low GI food than a normal person.

    Oatmeal, for example, can give devastatingly high readings to someone with pre-diabetes, though it is supposedly low GI. Whole wheat bread was proven to raise blood sugars just as high as white bread in people with diabetes in a recent study.

    People will have much better results if they ignore the Glycemic Index and pay attention to the total carbohydrate count of a serving of the food they eat.

    Every gram of that carbohydrate will require the same amount of insulin to be processed. If it is done slowly, you might not see a high blood sugar, but you will have elevated insulin, which will worsen weight gain and other symptoms of metabolic syndrome.

    You might find it interesting to research the extent to which the grain industry has been promoting the GI concept. I get quite a lot of fancy spam from PR firms working for organizations with names like "the Whole Grain Council" telling me how healthy low GI foods--like their grains--are for people with diabetes.

    They aren't.

  • rabagley

    9/16/2008 2:52:00 PM |

    Don't forget that sucrose is the one-two punch of damaging foods.  Half of it is glucose, a.k.a. blood sugar and the cause of the glycemic index/glycemic load values.  The other half is fructose, which causes your liver to immediately stop whatever it is doing and create triglycerides that directly raise your serum triglyceride number.  As in, one of the two numbers in the typical cholesterol test that actually means something (and means high risk).

    Sucrose creates the fats (triglycerides) in your blood and then guarantees that they make you fat through insulin's action that pushes triglycerides across liposome (fat cell) cell walls.

    It's especially important not to be fooled into thinking that GI and GL are the whole story of why sugar is bad for you.  Otherwise, you end up believing silly assertions like, "White grape juice is better for you than HFCS because white grape juice has a lower GI."  White grape juice is 80% fructose, so of course it has a lower GI than HFCS which is 55% fructose.  Doesn't make it any better for you.  It's just bad for you in a different way.

  • Francis St-Pierre

    9/17/2008 6:40:00 AM |

    This quote is right on the money, except for one detail. The author assumed corporations are against regulation, when in fact they love it and depend on it.

    What keeps drug companies in business? FDA approval requirements. What did food companies push for in Canada? Total ban on "low-carb" labelling.

    So the response to greed and corporatism is not regulation but a free marketplace where everyone is allowed to compete, big or small.

    Keep up the good work.

  • Ricardo Carvalho

    9/17/2008 11:23:00 AM |

    Perhaps governments should do better regulating food publicity and food labeling. For example, in the US they're trying to implement a system called "NuVal(tm) Nutritional Scoring System". Anyone here knows how it works? The official website is http://www.onqi.org and there are 2 articles about this at http://www.reuters.com/article/domesticNews/idUSN2750793620071128 and http://www.nutraceuticalsworld.com/articles/2008/07/online-exclusive-nuval-nutritional-scoring-system On the other hand, if this ONQI numerical algorithm incorporates the recommendations of the "famous" USDA Food Pyramid, and ignores evolutionary nutrition (paleodiet, which was low-carb, low insulin, no grains or dairy, etc.), it will certainly be of little use.

  • Anonymous

    9/17/2008 5:29:00 PM |

    Regarding the glycemic index and sugar control, I wonder how useful would it be to get hA1c tested in most people with heart disease?

    Wouldn't it be a good gauge of glycemic control? I wonder if l it could play a role in Dr. Davis' program... Besides checking just lipid parameters, perhaps those with lower hA1c would also have less plaque?
    And it should be useful to the patient too, so they can see how well they have been eating over the past several months.

  • Anonymous

    9/17/2008 6:03:00 PM |

    The GL (Glycemic Load) is a much better everyday tool to use than GI (Glycemc Index) and here's why: The GI number doesn't account for portion size.  So a drop of glucose and a cup of glucose both have a GI of 100 (it is the reference sugar, so it has the highest rating).  Obviously the former isn't going to do much to your insulin response, and the latter is going to be devastating.  Glycemic Load takes into account portion size.  It is a real-world application of the Glycemic Index.

    Once you know this, you realize that the published Glycemic Load number of any food can be miraculously halved...by eating half of it.  (Of course, you can also double it by eating a double portion!)  It puts the whole concept into practice in a tangible, useable way.

    Nutritiondata.com uses the GL exclusively and I highly recommend their site.

  • Anna

    9/17/2008 7:43:00 PM |

    I used to think the government should do a lot of regulating, because the corporate interests don't do a good job of self regulation.  Not so sure about government regulation now.  They gotten so much wrong, it's frightening.  

    With so much of our increasingly complicated lives involving things of which we have little common knowledge anymore (how our food is produced, what to do to optimize health and avoid illness, what chemicals are hazardous long-term, how to do even simple maintenance on our belongings, etc.), it is hard to be personably knowledgeable enough about everything, so it is easier to pass most of it on to the regulators and hope for the best.  But wow, that's a massive gamble that we don't seem to be winning very often.

  • abangkuraden

    9/29/2008 4:35:00 PM |

    Japanese who lives as long as 90++ years eats their rice at the end of their meals...

  • Anonymous

    5/13/2009 6:33:00 AM |

    The example of Kitavans and also having seen our Kerala people, it makes sense to totally disregard the GI or GL indexes. What is probably more important is the harmful lectin content of grains/legumes.

    If we could simply stop eating all grains/legumes and add nourishment that is missing because of our lack of sunlight (Vitamin D3) and lack of good quality meat (Vitamin K2 and Omega3), and possibly other lacking nutrients in our diet, we could also be healthy.

    I believe that a high GI carb is actually equivalent to saturated fat, because it will become one after the action of Insulin. Of-course this does not apply to diabetic and may not apply to people with low D3/K2.

    The low GI is probably not as good because it will give glucose for a long time and will make the glucose level high for a long time.

    For people like me who have already got leptin resistance cannot possibly avoid the glucose overload if they have to keep their fat mass below the level were our brain feels the leptin. The brain thinks that there is no fat at all to convert to glucose and the low blood sugar makes us feel dizzy.

    I think that obesity is caused by WGA and similar lectins that cause leptin resistance, compounded by the fact that we don't have D3/K2 which could fight against these ailments.

    I think White Rice is the only grain that has very little lectin and can be consumed easily. The south Indians mix it with sprouted legumes and grind it then ferment it before cooking it. This whole process effectively destroys the lectins almost completely. This is probably the only safe way to consume our legumes. Wheat etc the high lectin grains are poison for our health.

    -anand

  • buy jeans

    11/3/2010 12:31:05 PM |

    All of the above foods with GI's and GL's that match or exceed that of table sugar are made of wheat and cornstarch. Some, like Shredded Wheat cereal and rice cakes, don't even have any added sugar

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I lost 37 lbs with a fingerstick

I lost 37 lbs with a fingerstick

Jack needed to lose weight.

At 5 ft 7 inches, he weighed in at 273 lbs, putting his BMI at a sobering 42.8. (A BMI of 30 or above is classified as "obese.") In addition to lipoprotein(a), Jack had an extravagant quantity of small LDL (the evil "partner" of lipoprotein(a)), high triglycerides, and blood sugars in the diabetic range. With a heart scan score of 1670, Jack had little room for compromises.

Try as he might, Jack could simply not stick to the diet I urged him to follow. Three days, for instance, of avoiding wheat was promptly interrupted by his wife's tempting him with a nice BLT sandwich. This triggered his appetite, with diet spiraling downward in short order.

So I taught Jack how to check his blood sugars using a fingerstick device, what I call the most important weight loss tool available. I asked Jack to check his pre-meal blood glucose and his one-hour after-meal blood glucose and not allow the after-meal blood glucose to rise any higher than the pre-meal. For example, if blood glucose pre-meal was 115 mg/dl, after-meal blood glucose should be no higher than 115 mg/dl.

If any food or combination of foods increase blood glucose more than the pre-meal value, then eliminate the culprit food or reduce the portion size. For example, if dinner consists of baked salmon, asparagus, and mashed potatoes, and pre-meal blood glucose is 115 mg/dl, post-meal 155 mg/dl, reduce or eliminate the mashed potatoes. If slow-cooked, stone ground oatmeal causes blood glucose to increase from 115 mg/dl to 185 mg/dl (a typical response to oatmeal), then eliminate it.

Having immediate feedback on the effects of various foods finally did it for Jack: It identified foods that were triggering excessive blood sugar rises (and thereby insulin) and foods that did not.

What Jack did not do is limit or restrict calories. In fact, I asked him to eat portion sizes that left him comfortable. There was no need to reduce calories, push the plate away, etc. Just don't allow blood sugars to rise.

Six months later, Jack came back 37 lbs lighter. And he got there without calorie-counting, without regulating portion sizes, without hunger.

Comments (34) -

  • Martin Levac

    12/30/2010 5:14:00 AM |

    6 months, 37 lbs. That's pretty good. Immediate feedback is a strong tool for pretty much anything we do. When all we have is a scale, it takes a while for the result to show up. And we're never sure what we did that did it. But when we check blood sugar, we have the result right there and then. Like you said, we know exactly what's the cause and can act on it with total confidence.

  • Anonymous

    12/30/2010 3:37:50 PM |

    No problem with this but for the cost.
    At six (one before, one after, more if you're "grazing") sticks a day @.40 usd each test strip, we're spending $72/mo.
    This must be lowered somehow.

  • Anonymous

    12/30/2010 6:07:28 PM |

    To Anonymous,

    $72 / mo is only possible if you are eating different for different meals for the entire month. This is highly unlikely.

  • Jeff Consiglio

    12/30/2010 11:01:26 PM |

    Diabetics or pre-diabetics making dietary adjustments based on an objectively measured parameter, such as this, is genius. (I believe constant blood-sugar monitoring is what led Dr. Bernstein to adopt a low-carb diet.)

    But what about someone who's not diabetic...a person prone to hypoglycemic episodes for instance.

    Seems such an individual's tendency to "overshoot" insulin output in response to incoming carbohydrates would quickly (too quickly)lower blood-sugar levels...giving the false appearance that all is well. Even though much of that glucose got partitioned into fat cells.

    Keep up the good work Doc! I'm a personal trainer who regularly sends low-carb disbelieving physician clients of mine to your site. They can obviously receive this kind of info with a more open-mind from a fellow physician than from me.

  • Ensues

    12/31/2010 1:44:01 AM |

    I have a very similar story!  I lost 30 lbs in just over two months and this blog and Dr. Davis was the entire reason.  Total cholesterol down over 30% and triglycerides down over 50%.  LDL is much reduced too.  My only concern now is HDL.  It will not move an inch!  Started fish oil, then waited then started vitamin D supplementation.  Waited another couple months and earlier this week I started Niacin.  My HDL actually went down as Dr. Davis said it would while I was losing weight.  Then went right back up to 22 were it's been for years.  Might try wine and dark chocolate in moderation and if ALL ELSE fails I will have to submit to exercise.  My most sincere thanks Dr. Davis and keep posting actual patient experience.  It's very motivating.  Can't wait to read about a patient with a "stuck" HDL marker.

  • Anonymous

    12/31/2010 3:50:06 AM |

    It costs too much money to buy the strips. I know doctors can get give you prescriptions for the strips at lower costs, but that isn't something my doctor would do.Too bad, it sounds interesting.

  • Anonymous

    12/31/2010 4:53:31 AM |

    For those having issues with the cost, ask yourself this: what is my health worth?  This motivational tool is key to losing weight and changing your lifestyle intelligently.

  • Daniel A. Clinton, RN, BSN

    12/31/2010 7:05:33 AM |

    With 25.1% of Americans either diabetic or prediabetic, it's about time we start thoroughly and intelligently educating patients about how to maintain normal blood glucose levels. The reality is most Americans continue to eat an American diet, conclude blood sugar control thru diet to be impossible, and fall into a never-ending cycle of insulin resistance, pessimism, false comfort in high levels, and an exaggerated concern of hypoglycemia which they use to rationalize running around with blood sugars in the 200s. Proper education and a glucometer the two best tools to combat these epidemics, and yet only a tiny percentage of the population really understands the disease process and proper regimen to maintain good glycemic control. And it's no wonder with the ADA telling people who consider themselves "moderately active" (as most overweight, inactive people do) to eat 45 grams of carbs per meal.
    Dr. Davis, do you have any suggestions on how to develop a glucose tolerance test patients could perform on themselves at home simply using a fingerstick? Do you think there's value in something as simple as checking a fasting blood sugar, drinking a 20 oz Coke, and then taking fingerstick readings at 1 hour and 2 hours?

  • Peter

    12/31/2010 11:22:24 AM |

    What I learned from testing was that brown rice and black beans raise my blood sugar 60 or 70 points, and that if I stayed away from grains, beans, and sugars, my blood sugar doesn't budge.  It didn't take many strips to figure this out, the bigger expense is that rice and beans were way cheaper than fish, meat, and cheese.

  • Anonymous

    12/31/2010 2:36:40 PM |

    Concern for one's health is a straw man, it's usually everyone's concern; however cost IS an arbiter, otherwise we'd all have "Cadillac" health plans. Technology will lower the strip costs, or eliminate them. In the meantime some do without.

  • Anne

    12/31/2010 2:48:04 PM |

    It is easy to find a free meter and it will come with at least 10 strips. This is enough to tell you if your blood sugar is spiking after eating. That is what I did and then I was able to convince my doctor that, in spite of my "normal" fasting BG, I needed a prescription for testing supplies as my postprandial blood glucose was spiking over 200.

    Once I figured out what foods were causing my blood sugar to go high, and totally eliminated these foods, testing became much less frequent. The only time I test now is if I add in a new food.  I will also test throughout the day every once in a while to be sure my BG is not creeping up even with the low carb lifestyle.

    When I started doing this a little over 2 years ago, I lost 15-20 lbs and have remained stable. I no longer have daily episodes of hypoglycemia caused by crashes after a blood sugar spike.

  • gkamp

    12/31/2010 3:43:19 PM |

    To penny-wise, pound foolish anonymous,

    I would tend to bet that the price of strips is kept artificially high and it is not lack of technology that is the problem.  However, think of what you'd spend on a dinner out, a movie, or even a doctor's visit--and a doctor's visit won't give you half of the information about your health that a canister of strips will give you.  Anything a doctor does is a single snapshot in time, not ultimately helpful on a day-to-day basis.  Testing your blood sugar systematically for various foods works if you pay attention to what it tells you and modify your behavior accordingly.

  • Derek S.

    12/31/2010 5:57:18 PM |

    Anonymous,

    No, health concern is most definitely not a straw man.  Yes, most people will give lip service to their health being a top priority but words mean little.  If you observe the hierarchy of priorities in that person's life based on their ACTIONS you will usually quickly see the truth of the matter is that health is NOT one of their top priorities.  It is called cognitive dissonance and it is endemic to our society, unfortunately.

    If someone is not willing to give up their Starbucks, movies, pricey wines, or any number of other extras in their life in order to obtain something that has tremendous possibilities for improving their health then by their actions they are stating clearly their priorities.  Words mean little at that point except to misdirect, evade or confuse the issue.  The actions tell the tale.

    I would end by saying that your statement about health usually being everyone's concern is simply not true...not because most everyone doesn't say it, because they do, but because most everyone doesn't act according to their words.  It has always been true that you can tell a tree by it's fruit.

  • Derek S.

    12/31/2010 6:03:56 PM |

    I also want to point out that the old biblical term for cognitive dissonance is "hypocrisy".  I usually avoid that term nowadays, though, since it cuts too close to the heart of the matter and therefore makes people very uncomfortable if not downright offended.

  • Dr. William Davis

    12/31/2010 8:10:55 PM |

    Thanks, Anne, for making a crucial point: Keep costs low by only assessing a previously untested food or combination of foods.

    In other words, if you know that a 3-egg omelette with olive oil and green peppers results in an excellent blood sugar response, don't bother to check it again.

  • Might-o'chondri-AL

    1/1/2011 12:43:45 AM |

    "Stuck" HDL was posted 30 Dec. so this may  still interest some.

    The Linosa study gives low HDL as 54% heritable, and low HDL accompanied with concurrent high Triglycerides as 31% heritable.

    The Erasmus Ruchpen study classes HDL as 43% heritable; with both sexes having the same HDL and Triglyceride genetic pre-disposition.

    The Healthy Twin (Korea) study classes low HDL as 77% heritable and Triglycerides as 46% heritable.

    Our individual genetics are probably not from those study pools. However, it has been theorized that the genetic tendency for most Caucasians (like the Korean twins)is to low HDL.

    The ratio of Apoliprotein B to Apoliprotein A1 has an inverse effect on HDL. Doc has described to us how he clinically deals with ApoB;  HDL reading might not "move" much but being pro-active is preventative.

  • e4e

    1/1/2011 4:46:55 AM |

    @Ensues,

    You might try increasing sat fat a little. Coconut oil, butter, lard used in cooking can help drive up HDL. It also drives up total cholesterol, but as a ratio, HDL goes up more.

  • Anonymous

    1/1/2011 11:13:25 AM |

    Metformin can help with weight loss in the Non Diabetic patient. A great addition to the glucose meter

  • Anonymous

    1/1/2011 12:10:20 PM |

    $72 a month is cheaper than weight watchers.

  • Anonymous

    1/1/2011 12:49:28 PM |

    Taking niacin to raise HDL worked for me, but it raised my fasting GLU to over 160. Another dangerous side effect for me is that even a small dose will cause me to fly into a rage with the least provocation.

    Wal-mart sells a test kit with 50 test strips for under $20 (side-kick).

  • steve

    1/1/2011 4:47:20 PM |

    This raises a good question: what is the ideal weight for any individual?

  • Anne

    1/1/2011 5:28:01 PM |

    Ensues, Here is a post on Inhuman Experiment about  hibiscus tea  increasing HDL and lowering LDL.

  • Roberto

    1/2/2011 7:51:17 PM |

    Dr. Davis

    I had my HbA1C checked while I was eating roughly 60% of my calories from carbohydrate and it was 4.9%. After 3 months on a low-carb diet I had it checked again and it had risen slightly to 5.0%. How could this possibly happen?

  • Ensues

    1/2/2011 11:47:58 PM |

    @Many...

    Thanks for the tips.  I never cease to be amazed by how supportive this community is.  I was a SAD poster child always "trying" to follow government guidelines.  I made a list of all of the "little" changes I made to conform better.  Whole wheat pasta, skim milk, whole wheat bread, no chicken skin etc etc etc.  My damaged metabolism took hit after hit after hit.  My triglycerides were over 1000.  My PCP advised to avoid greasy fried foods.  It's comical (and sad) looking back on it.  My glucose meter has a permanent place in my laptop bag and my weight goes down every week AND my health improves. Thanks again for the suggestions and data.

    Ensues

  • Anonymous

    1/3/2011 12:14:39 AM |

    I eat the same foods everyday, so I don't have to test my blood sugar very much. I save money on test strips (I use freestyle lite) and I save money since I buy food in bulk.
    I think it's important to not eliminate foods just because they raise blood sugar. It's also the combination of foods that affects the glycemic response. There are ways to eat oats and other potentially high glycemic foods with minimal glycemic response. I don't like elevated sugar, but after trying to live on flax alone, I became too depressed to continue. Flax is ok for 1 meal, but that's it for me. One example. I eat semi-pureed sauerkraut with glucomannan and dulse flakes and I get less glycemic response than with sauerkraut alone.

  • Anonymous

    1/3/2011 1:09:19 AM |

    I forgot to post my other example of food combining. Quick oats can be processed in a food processor for 2-3 minutes and added to nut butters or perhaps even added to eggs and meats, although I've only tried oats with nut butters. If I eat oats alone once daily, I spike to 150. If I eat oats twice daily, I don't go above 120, so it's about previous meals and also the time of day for me.

  • Travis Culp

    1/3/2011 9:21:33 PM |

    Though it's bizarre to me that spending money on health isn't widely accepted as being a good investment, there is a fairly easy way to avoid doing so and still get this information.
    Why doesn't the good doctor create a central repository that lists various foods/meals and the BG response to them. There must be variation between individuals, but generally speaking, a "bad" food is a bad food. I understand that the point of the process is to rein in recalcitrant patients who need to see what the food is doing, but for those who don't want to spend the money or don't want to do this for another reason, but who do have self-control, we could just share info on which foods cause the biggest response. Presumably they would be grains, sweeteners, high-lactose dairy and fruit eaten on an empty stomach. Meals comprised of mostly meat and green veggies with a serving of carbs (25g or so) should not elicit such a response.

  • Anonymous

    1/5/2011 4:44:12 PM |

    Travis Culp,
    The 'Glycemic Index' may be what you are looking for. To see a very good listing and discussion check out www.mendosa.com
    At his site there is a link to Excell listing of GI, this is nice as you can reorder it in assending /desending order. There are also  a book.
    Ed

  • Cathy

    1/5/2011 5:00:32 PM |

    My husband was diagnosed as a diabetic and I am prediabetic so I read Dr. Bernstein's book and started testing, testing, testing as suggested. When I went to get the testing strips refilled the pharmacy said I could not get more yet as I was using them too often!  After explaining what I had done and that I did not know I was only allowed to use a certain number of sticks a day (two), they refilled it but I think that is wrong for the insurance companies to restrict that.  I was glad to read the posts that once you know a food combination does not elevate sugars then you don't need to test then.  That helps a lot.  Thanks for all of your input.  It is a big help to me.

  • Complications of Diabetes

    1/7/2011 9:25:08 AM |

    Really liked the way you used to help Jack loose his weight. The results are pretty good and appreciable.
    Thanks for the post and awaiting to read more.

  • jem

    1/12/2011 6:53:14 PM |

    Is it really possible to get NO increase in BG?

    I am using this plan and have stopped testing that a m fasting (which is always elevated, for some reason).
    This has made me way less crazy.

    So back to my question....
    Yesterday my pre breakfast was 70; pp was 96.
    Lunch was 92; 102

    I seem to always have some increase so when peop say they have none, do they really mean none?

    The other question; Is the 1 hr pp enough?
    When I was testing 2 hr the reading was always higher.

    So, as you can see, there's much less stress involved w 1 hr pp testing...but am I kidding myself?

  • Dr. William Davis

    1/12/2011 7:29:15 PM |

    Jem--

    Some people digest and process carbohydrates more slowly, or the mix of foods slows the process.

    Find your peak by performing every 30 minute checks, then use that time in future.

  • Anonymous

    1/13/2011 4:38:12 PM |

    Does anyone have any experience with Mulberry Zuccarin for glucose control?  I read an article about it and came back here to find this thread, hoping for some insight.  Just snake oil, or is there something to it?

  • Karen

    2/28/2011 1:17:44 AM |

    For people concerned about cost.  I bought a walmart store brand meter for 9.00 and 50 strips is 20.00   This meter/strips is a good brand,  have no trouble with it.  the pharmacist told me she used it personally with no issues.  I don't test every day every meal,  Great price.

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Explosive plaque growth

Explosive plaque growth

Every once in a while, we will see someone experience more-than-expected rate of coronary plaque growth, a sudden jump in heart scan scores. I'm talking about increases in score of 50%, even 100%, sometimes despite favorable lipid and lipoprotein patterns.

It's not always easy to pin this phenomenon down, since we often detect it after a year or more on a repeat heart scan. It would be wonderfully insightful to perform heart scans more frequently and track plaque growth more precisely, but of course, radiation exposure is the most important limiting factor, as is cost.

So this list is, admittedly, speculative. It is based on observation, on presumptive associations between events and heart scan scores. But, judging from what we do confidently know about coronary atherosclerotic plaque, I think these observations make physiologic sense.

These are the sorts of increases in heart scan score that can scare the heck out of you, silent yet explosive growth of coronary atherosclerotic plaque that can grow with no warning whatsoever.



Image courtesy Wikipedia and the United States Geological Survey.









Factors which I have observed to possibly be responsible for explosive plaque growth include:

--Overwhelming tragedy such as death of a loved one, financial ruin, divorce. One of my early and catastrophic failures was a young man in his early 40s who, in the space of just a few months, suffered the loss of his mother, a brother, and his mother-in-law, while working a high-stress job. His heart scan score doubled from around 100 to 200 in one year, despite perfect lipoproteins. He had a heart attack shortly after the second score, despite a normal stress test just months earlier. (Pessimism is tragedy's weak cousin, but one that still holds power to corrupt our otherwise best efforts at plaque reversal.)

--Substantial weight gain. In the early years of the Track Your Plaque program, before it was even called "Track Your Plaque," I witnessed a man more than double his score from 1100 to 2400 in 18 months just by allowing himself to gain 40 lbs. (I don't know what became of him. His life apparently suffered other disasters, as well, and we lost track of him.)

--Poorly-controlled diabetes. High blood sugars out of control have yielded explosive growth.

--Kidney disease--However, I am uncertain of how much this overlaps with a deficiency of vitamin D's active form, 1,25-OH-vitamin D3, the form that is often deficient in people with dysfunctional kidneys.

--An inflammatory disease that is out of control, e.g., rheumatoid arthritis.

--This is very speculative, but I've witnessed explosive growth after vaccine administration that yielded strange viral-like symptoms. In this one instance, the man was getting heart scans (on his own) every three to six months and described a severe illness following a vaccine administered in preparation for travel out of the U.S.

--Unrecognized low thyroid function--i.e., hypothyroidism. This is easily corrected with thyroid hormone replacement.


These factors can also be relative and they can be overcome. Look at our current Track Your Plaque reversal record-holder: a 53-year old woman who dropped her heart scan score an amazing 63% despite the loss of a loved one during the 15 months of her program. Despite an overwhelming tragedy, she overcame the potential adverse effects and set a record, probably a record for the entire world.

Comments (3) -

  • chcikadeenorth

    12/11/2007 2:54:00 PM |

    thank you, very timely and informative, explains allot of my increase as well.But I am working to become a Low Plague Poster Baby Boomer.

  • Anonymous

    12/11/2007 11:25:00 PM |

    For someone that has explosive plaque, how would you try to treat?  Would lowering matrix metalloproteinase by prescribing doxycycline be an appropriate next step?

  • Dr. Davis

    12/12/2007 3:17:00 AM |

    First, consider correction of the cause.

    Unfortunately, a cause is not always identifiable, at least one you can do something about. Yes, anti-inflammatory strategies against MMP might be useful. Otherwise, there is, with present knowledge, no specific therapy for, say, grief.

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