Is it mainstream or alternative?

A question I get about once a week: "Is your program a kind of alternative medicine?"

Our program for control and reversal of coronary plaque using CT heart scans applies an eclectic panel of tools to achieve its goals. We use high-tech methods like lipoprotein analysis and CT heart scans; nutritional supplements like fish oil, vitamin D, and l-arginine; diet strategies and "functional foods" (using foods as a therapeutic tool); and conventional medication.

I don't consider this approach "alternative" in the sense that it uses unmeasurable or spiritual strategies. But I don't consider it mainstream, either, since current mainstream practice of heart disease prevention is far less rigorous with far less satisfactory results.

I think I can sum up the Track Your Plaque approach by saying that we use tools that work. Our measure of success is whether or not your heart scan score is stopped or reduced--that's hard to fudge. You can call it what you will, but I call it the best program for heart disease prevention I know of, alternative or mainstream.

Want to see someone turn diabetic?

If you want to witness the transformation of someone into a pre-diabetic or diabetic, put them on a low fat diet.

Dr. Dean Ornish's program, detailed in his books, Dr. Dean Ornish's Program for Reversal of Heart Disease and Eat More, Weigh Less , are woefully outdated in 2006. Yet the low fat notion continues to show up in the consciousness of people I talk to about heart disease reversal.

"I'm already on a low fat diet. Do you think my heart scan score has reversed?"

Highly unlikely. What Dr. Ornish (as a non-cardiologist, by the way) failed to recognize is that what he did manage to reverse in a small number of people is something called "endothelial dysfunction", but he did not reverse or shrink coronary plaque.

Given the limitations of technology when the Ornish concept got its start, it appeared as if reversal was obtained. In reality, all his approach accomplished was a relaxation in tone of abnormally constricted arteries, thus giving the appearance of reversal. Increased artery tone, or endothelial dysfunction, is extremely common when atherosclerotic plaque is present.

Any cardiologist will tell you that there are many ways to reverse endothelial dysfunction: exercise, weight loss, cholesterol drugs, drugs for high blood pressure, fish oil, hormonal therapy, vitamin C, l-arginine, etc. There is nothing special about a low fat diet.

In fact, Track Your Plaque followers will recognize that a low fat diet is, in fact, potentially harmful, particularly when low HDL or small LDL is part of your pattern.

Let's bury the outdated ideas of the Ornish low fat diet once and for all. It doesn't work. All it may do is confuse you and set you back from your real coronary plaque reversal program.

Inulin: A fiber for weight loss

Here's an interesting product that seems to be gaining some popularity for weight loss: Inulin.

Not to be confused with "insulin", with which it is completely unrelated, inulin is a naturally-occurring plant fiber. It's found in broccoli, asparagus, celery, etc. Like beta-glucan from oats or pectin, inulin is a so-called soluble fiber, a fiber that assumes a gel-like consistency when exposed to water.

Inulin has the effect of increasing satiety, or the sensation of fullness. This cuts your craving for foods. I've tried it recently and I prefer it over glucomannan, another soluble fiber for satiety.

The people at Stonyfield Farms have been adding inulin to their yogurts from some time. The nutritionist at the company tells me that there's 2-3 grams of inulin per 6 ounce container of their yogurt.

You can also find inulin as a supplement that you can add to foods, available from some health food stores and online supplement companies. I came across a neat product called Fiber Choice that's now being distributed widely throughout the U.S. I tried their Weight Management version. It was a delicous strawberry taste. The label says take two chewable tablets twice a day, but I found that two tablets three times a day somewhat better. It's best taken around 30-60 minutes prior to each meal and it causes you to be fuller with less food. One caution: It'll cause loads of gas, especially in the beginning. For that reason, you might try starting with a smaller dose, or start on the weekends when you have the option of some privacy!

More info on the Fiber Choice product can be found at their website, http://www.fiberchoice.com.

Disclaimer: I have no relationship with the manufacturer of this product. I'm simply passing on some thoughts on my experience with this interesting possibility for weight loss.

Will you recognize the truth when you see it?

Do you ever wonder that, if the truth were given to you, that you'd recognize it as such? Or would you dismiss it as just another bunch of nonsense?

After all, you and I live in the Information Age. It means that we have access to mountains of information like never before in human history. But it also means that the truth is often drowned out by an avalanche of mis-truths, sales pitches and marketing, and just plain nonsense.

This struck me the other day when I was talking to a patient.

64 years old with a high heart scan score placing her at significant risk, she looked confused. I'd just described the multitude of causes of coronary plaque that we'd uncovered. The heart scan alone had been a shocker.

"I don't understand. My doctor told me that I had nothing to worry about. I've known him for years and he knows me really well. He did a stress test. That was fine. I don't get all this other stuff you're telling me--lipoprotein whatever..."

Despite my efforts to help her gain an understanding of our intensive approach, she just became increasingly more frustrated. "I just don't think I can do this."

That's the last I've heard from her. As far as I know, she's returned to the comfort of her family doctor who has reassured her over the years. And perhaps there's some good in that. But I do fear for the day when, unexpectedly, she suffers some catastrophe that we told her was coming sooner or later unless real preventive efforts were started.

You could say that she failed to recognize the truth when it was given to her-- boldly, unadorned, and with far greater scientific certainty than the casual reassurances she was accustomed to. But, unfortunately, that's all that some people want.

Don't neglect the basics in your heart disease reversal program

Carl loved new ideas and novel approaches. You could tell by the sheer number of nutritional supplements he took. His list had grown to 18 different supplements over the past two years.

Carl came to me for coronary plaque regression. Lipoprotein analysis did uncover several previously unsuspected abnormalties, most notably small LDL particles and lipoprotein(a). In addition, Carl's LDL cholesterol ranged between 111 mg-156 mg and he was clearly hypertensive, with systolic blood pressures consistently around 150-160. (Recall that people with Lp(a) are more prone to hypertension.)

Carl was more than willing to have his lipoprotein(a) reduced. We did so with niacin and testosterone and the level dropped to near zero. Likewise, we corrected his small LDL pattern with niacin, fish oil, and a reduction in processed carbohydrates.

But Carl really resisted doing much about his LDL cholesterol and high blood pressure. I got the sense that these "boring" issues simply didn't interest him. After all, LDL cholesterol and blood pressure were the stuff of TV commercials and the popular conversation propagated by drug companies.

Carl's follow-up heart scan, however, finally persuaded him: a 24% increase in one year, likely due to the neglect of the basic issues.

I liken Carl's case to being like the teenager with a new car who polishes the paint to a bright finish, puts new wheels and tires on it, spruces up the interior with various doodads--but then fails to change the oil. Sometimes it's the most basic issues that can diminish your success.

Issues like LDL cholesterol and high blood pressure aren't the most glamorous, but they do count in your coronary plaque control program.

Is your doctor a hospital employee?

There's a disturbing trend that's growing--silently but rapidly.

In Milwaukee, three hospital systems compete for the local health care dollar. To gain more control over revenues and the routing of patients, the hospitals are aggressively hiring physicians to work for them. I've witnessed many of my cardiology colleagues, primary care doctors, and a substantial number of procedural specialists enticed by the offers made by hospital employers.

This phenomenon is not unique to Milwaukee but is being used in many, perhaps most, major cities in the U.S.

This means that physicians are employees of the hospital. That way, employee-physicians are obliged to use only the hospital system that employs them. In the old days, your doctor could use any hospital he/she desired, depending on the quality, location, facilities, etc. Now, many physician-employees are given no choice but to use the hospital that pays their salary.

That by itself is not necessarily bad. But combine salary with incentives for bringing in patients for hospitalization and procedures--that the rub. In other words, physician-employees are incentivized to generate more revenue for the system, just as employees in many other industries.

If you're a salesman for an insurance company, your job is to bring in more business. If you're a worker on an auto production line, you're expected to meet certain quotas. These same principles are now being applied to many physicians.

How does this affect you? Well, if your physician--especially procedure-driven specialists like cardiologists, general surgeons, orthopedists, etc.--is a hospital employee, BEWARE! Do you really need that procedure, or is your doctor suggesting you have a procedure because it will add to his track record?

Prevention? In this model of health care, why bother? It certainly doesn't pay for a hospital to keep you well. Then why should your physician-employee?

Be careful who you're dealing with. If your physician is a hospital-employee, don't bet on getting preventive care. It's more likely you're that just a future source of revenue when it's time for your bypass operation, hip replacement, carotid endarterectomy, etc.

What more powerful argument is there for increased self-empowerment and information for health care consumers?

Take a walking vacation

If you're planning a vacation, why not consider a walking vacation?

The concept is really taking off. All you need is a pair of comfortable shoes and an interesting locale. More and more services are popping up to help you plan fun and interesting destinations and itineraries. One such catalog can be found at http://walking.about.com/od/tours/a/walkingvacation_3.htm

Lengthier walks may require some advance planning and toting some supplies. Don't forget the water!

From a health viewpoint, a walking vacation sure beats the heck out of a cruise that packs on 12 pounds of extra weight from the 24-hour a day buffet. If you're in the midst of a weight loss effort, several hours of walking through interesting locales and scenery can make it effortless.

There's loads of neat places to visit from a walker's perspective. One interesting website is www.waterfallwalks.com that lists trails that provide spectacular views of waterfalls.

Another variation on this theme is biking vacations. My wife and I are trying to set the time aside for a biking tour of wineries in the French countryside. That's our kind of multi-tasking!

"Expanded indications for implantable defibrillators"

So reads the headline on a magazine I received recently (along with thousands of my colleagues) from a major hospital system.

It goes on to say: "In January 2005, indications for implantable cardioverter-defibrillators (ICDs) were substantially broadened [emphasis ours] to include most patients with a left ventricular ejection fraction (EF) of 35% or less. This change translates into a 2- to 3-fold increase in the number of Medicare beneficiariries eligible for ICDs."

Ka-ching!!! Hear the money piling up in the bank?

The device manufacturers are constantly churning data and lobbying for reimbursement to expand the use of their devices to more and more people. Defibrillators in particularly are generally a $25,000 to $50,000 opportunity for the device manufacturer alone, not counting the costs incurred at the hospital for implantation.

Beware. As reimbursement for stents and other procedures diminishes, expect a sudden "demand" for more and more people to get implantable defibrillators. Better yet, stay away from the whole issue by preventing your heart attack.

Get a heart scan--but then don't delay taking action!

I just came from one of the local hospitals after having performed a heart catheterization on a patient I met earlier this week.

Jack had gotten a heart scan a year ago with a score of 246, placing him in the 76th percentile. The "event" rate with this percentile rank is around 3% per year--not very high but enough to pose risk over a long period.

Jack chose to ignore his score. After all, the pressures of work at the University, maintaining his home and yard, etc. consumed all his energies. He came to my office--now one year after his scan--and told me about the chest pressure he was getting. Initially, his chest pains occurred with extended walking. In the past week, however, Jack was experiencing chest pressure with just walking 30 feet.

This pattern of increasing symptoms is called "accelerated angina", meaning that Jack was rapidly heading towards a heart attack. So I advised a heart catheterization in near future.

Jack's catheterization showed extensive plaque including a 50% blockage in the mainstem artery and 90% in the artery to the front of the heart (left anterior descending artery). Jack is going to have a bypass operation tomorrow.

What if Jack hadn't ignored his heart scan from a year ago? Well, I'd be very confident in saying that he would not be undergoing bypass surgery tomorrow.

The lesson: Don't dilly-dally on taking action to keep your plaque from growing. While it's not an emergency, it can easily become one if you choose to ignore your scan.

Feel that nudge in your back?

You feel that nudge in your back? That's your local hospitals competing for your bypass surgery business.

Just this morning while watching a morning news show, I saw three advertisements for hospital bypass surgery programs. One ad featured a man in his 50s telling his story:"The cardiologist determined immediately that I needed a triple bypass operation. My family and I are very grateful to _____ hospital!"

In what other field is failure celebrated so prominently? When I see these ads, I hear "My doctors failed to provide early detection and then prevent what became a life-threatening condition, even though heart disease is a chronic process that requires decades to develop." What if our man said instead,"I had a heart scan and my score was high. So I was shown why I had so much plaque. They then showed me how to control and even reduce the amount of plaque I had. I'm living safely and symptom-free without need for surgery or procedures."

Of course, the hospital is out $60,000-100,000 for the surgery. How else could they afford ad campaigns costing several million dollars a year? See these advertisements for what they are: Marketing generated by profit-seeking businesses competing for your dollars--lots of them.
Is pomegranate juice healthy?

Is pomegranate juice healthy?


Pomegranate juice, 8 oz:

Sugars, total 31.50 g

Sucrose 0.00 g

Glucose (dextrose) 15.64 g

Fructose 15.86 g




In your quest to increase the flavonoids in your diet, do you overexpose yourself to fructose?

Remember: Fructose increases LDL cholesterol, apoprotein B, small LDL, triglycerides, and substantially increases deposition of visceral fat (fructose belly?). How about a slice of whole grain bread with that glass of pomegranate juice? The Heart Association says it's all low-fat!


(Coming on the Track Your Plaque website: A full in-depth Special Report on fructose in all its glorious forms and whether this is truly an issue for your health. Fructose tables and the scientific data to establish a safe "threshold" value will be included.)

Image courtesy Wikipedia

Comments (20) -

  • Anonymous

    7/19/2009 1:45:42 PM |

    all should keep in mind that 4 grams of sugar is equal to one teaspoon.  31 grams is 7 teaspoons plus; not exactly what one would think in what is promoted to be a healthful product!

  • John

    7/19/2009 2:15:04 PM |

    Like most juices, pomegranate juice just has too much sugar.  There is a reason why a juice glass is very small!

    I don't buy pomgrante juice anymore, and when I did I would water it down.  100% is very expensive too.

    Another thing about pomegranate juice, people might be surprised to find that many of them are not 100% pomegranate, but a blend of several juices.

  • Andrew

    7/19/2009 3:59:34 PM |

    At what point do the positive health benefits of pomegranate outweigh the bad parts of fructose?

  • Tom

    7/19/2009 4:20:58 PM |

    Thanks for your great blog! Your information on wheat and sugar is a must read for anyone serious about their health. I like your blog so much, I added a link to it at my blog at http://eatingandfasting.blogspot.com/

  • Anonymous

    7/19/2009 6:07:12 PM |

    Dr. Davis,

    Are you implying that there is no difference between a glass of Kool-ade and a glass of fresh Orange Juice?

    IMO, the problem is not fructose. The problem is highly refined sugar sources that are isolated from their highly complex natural matrix of fiber, vitamins, minerals, flavanoids, antioxidants, enzymes, amino acids--all which act in synergy together.

    That's why PJ reduced atherosclerosis by 35% compared to control group, lowered BP by 20%, increased antioxidant status, and did not raise blood sugar.

    (FYI, I happen to have heterozygous FH and drink daily one full glass of PJ along with one full glass of concord grape juice, and 97% of my LDL particle size remains large, my blood sugar is perfect, and my apo B is not too high. I do avoid refined sugars and carbs, however.)

    So please, Dr. Davis, don't compare an apple with a candy bar.

  • AJ

    7/20/2009 4:52:14 AM |

    Guava juice used to be my particular poison - literally speaking. But it's just not worth the hit to my metabolism. It's been awhile since I last drank any fruit juice and it will be never before I drink it again.

    It's an uphill battle to get people to realise the dangers of fructose, particularly when food manufacturers are allowed to put "No sugar added" on the label. Have them put the grammes of sugars the whole bottle contains on the front of the container in large bright type. It won't stop everyone, but it may help a few people make healthier choices.

  • JC

    7/20/2009 10:55:48 AM |

    Pomegranate juice more than triples PSA doubling time.Is that significant?

  • Peter

    7/20/2009 1:56:43 PM |

    I like to dilute the pomegranate juice with vodka.  That way I only use a couple of ounces of juice at a time, minimizing the fructose but still getting some flavanoids.  Of course once the long term study on this regimen comes out I may have to revise my view.

  • Dr. William Davis

    7/21/2009 3:28:52 AM |

    It's the same flawed logic of "healthy whole grains": If it contains something good (B vitamins, fiber), then it must be good. And it must be even better when consumed in greater quantities.

    Just because it contains one or two desirable ingredients doesn't mean that the entire "package" is desirable,

  • niner

    7/21/2009 5:00:09 AM |

    There's always pomegranate extracts.  You can get the polyphenols in a pill without all the sugar.  I'd be interested in what Dr. D thinks about this form of "sugar-free pomegranate".

  • JC

    7/21/2009 11:19:40 AM |

    Dr Davis,What about the research on pomegranate juice and PSA doubling time?

    Can you also comment on the reported benefits of cranberry juice in preventing urinary infection?

    Thanks,JC

  • Jonathan Byron

    7/21/2009 3:12:18 PM |

    You are absolutely right that fruit can contain large amounts of fruit sugar, and that large amounts of fructose can have serious consequences. The idea that fruit juice must be good (in any quantity) is not supported by the evidence.

    But fruits are more than sugar and moderate amounts of fruits and fructose are not inherently bad - the question is what is reasonable. For those of us with fatty liver, certain patterns of dyslipidemia, or a GI fructose intolerance, the ideal amount is very low. For those who don't fall into that category, the ideal amount of fruit is somewhat greater (but probably less than most people assume).

  • Anna

    7/22/2009 10:22:04 PM |

    I can't remember the last time I saw someone outside my household drink juice from a small juice glass.  Most people I see drinking juice are consuming quantities of juice that practically rival a 7-Eleven Big Gulp.

    Many days I squeeze a half orange to make a couple ounces of OJ to mix with cod liver oil to make the CLO palatable for my young son.  

    To fill a 4 oz juice glass (with about 3-3.5 oz juice), it takes 1-2 oranges, which means that larger glasses of OJ contain the sugar of a whole lot of oranges!  Who would ever eat that many whole oranges in one sitting?

    Also, I know from using a glucose meter that OJ sugar is nearly instantly into my blood stream (and that isn't even measuring the affect of the fructose portion of sugars.  The glucose spikes an insulin response and later a nasty feeling low BG.  So I approach fruit juices with extreme caution and limitations on both quantity and frequency.  I eat whole lower sugar fruits in extreme moderation (avoiding higher sugar tropical fruits).  I focus more on non-starchy veggies rather than fruit, anyway, because veggies are high in the nutrients I want without the excess sugar that fruit has.        

    Not long ago I was in waiting in line at a Starbucks to order an Americano (lack of local coffee shops at that particular suburban area) and right next to me a dad was reading aloud to his young daughter the number of grams of sugar from her “fresh-squeezed 100% fruit juice” bottle label. He noted incredulously there were 30-something grams of sugars per serving and there were 2.5 servings per bottle. He said  â€œwow, that’s a lot of sugar in that bottle”. I thought to myself, wow, here’s a dad who is “getting it”, so I said to him, “there’s 4 grams of sugar to a teaspoon, so that’s at least 7-9 teaspoons of sugar per serving, very nearly the sugar content in soda.”

    His response was, “but it’s fruit sugar, and she doesn’t eat enough fruits and vegetables, so I guess that’s ok.” Sigh. I let it go, and ordered my Americano (unsweetened).

    I've had many interesting conversations with a glycobiologist colleague of my husband's.  He has confirmed I'd be wise to keep all sources of fructose intake to a minimum, as well as being especially wary of concentrated sources of fructose.    I'm sure he follows his own advice; he's looks at least 15 years younger than his 60 years - lack of AGEing, I guess.

  • trinkwasser

    7/29/2009 6:04:30 PM |

    Tell this stuff to a dietician and they won't believe you "but it's low fat!"

    My BG meter tells me fruit juice is an exceedingly toxic substance, and most of my once favourite fruits aren't much better.

    Fortunately it permits me to eat a few berries, but I'd rather get my bioflavinoids etc. from vegetables.

    IMO there's a balancing point between the beneficial and non-beneficial properties of many foods, we probably evolved to deal with small acute doses of toxins but fall apart with chronic exposure to high levels of the same stuff, and all the bioflavinoids and vitamins don't outweigh the damage.

    I just stuffed some strawberries in my face following my lamb chops and runner beans, but only a few, and I washed them down with a fine Bordeaux, that'll about achieve a balance.

  • Barrry

    2/22/2010 12:58:33 PM |

    i have been using Pomegranate juice for 3 years every day after i had 2 stents placed. i also had type 2 diabetes. It has worked very well for me and has not effected my A1c in the least. My cardilogical nuclear studies have been perfect. i am a believer my opinion this stuff can save your life.

  • EMR

    2/24/2010 1:33:43 PM |

    ink it should be avoided by sugar patients.It contains almost a spoon of sugar...though with wheat bread the whole effect of the meal is balanced.

  • Anonymous

    3/8/2010 3:03:37 PM |

    http://www.nutraingredients-usa.com/Research/Pomegranate-juice-shows-possible-diabetes-benefits

    Quit being sugar paranoid.

  • buy jeans

    11/3/2010 3:09:20 PM |

    Remember: Fructose increases LDL cholesterol, apoprotein B, small LDL, triglycerides, and substantially increases deposition of visceral fat (fructose belly?). How about a slice of whole grain bread with that glass of pomegranate juice? The Heart Association says it's all low-fat!

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