Biscuits and Gravy



Biscuits and gravy: the ultimate comfort food . . . one you thought you’d never have again!

The familiar dish of breakfast and holiday meals is recreated here with a delicious gravy that you can pour over piping hot biscuits. Because it contains no wheat or other unhealthy thickeners like cornstarch made with “junk” carbohydrates, there should be no blood sugar or insulin problems with this dish, nor joint pain, edema, acid reflux, mind “fog,” or dandruff—life is good without wheat!

While the gravy is also dairy-free for those with dairy intolerances, the biscuits are not, as there are cheese and butter in the biscuits, both of which are optional, e.g., leave out the cheese and replace butter with coconut or other oil.

Makes 10 biscuits

Gravy:
2 tablespoons extra-virgin olive oil
1 pound loose sausage meat
2½ cups beef broth
¼ cup coconut flour
½ cup coconut milk (canned variety)
1 tablespoon onion powder
1 teaspoon garlic powder
½ teaspoon sea salt
Dash ground black pepper

Biscuits:
1 cup shredded cheddar (or other) cheese
2 cups almond meal/flour
¼ cup coconut flour
¾ teaspoon baking soda
½ teaspoon sea salt
2 large eggs
4 ounces butter, melted (or other oil, e.g., extra-light olive, coconut, walnut)

To make gravy:
In large skillet, heat oil over medium heat. Sauté sausage, breaking up as it browns. Cook until thoroughly cooked and no longer pink.

Turn heat up to medium to high and pour in beef broth. Heat just short of boiling, then turn down to low heat. Stir in coconut flour, little by little, over 3-5 minutes; stop adding when gravy obtains desired thickness. Pour in coconut milk and stir in well. Add onion powder, garlic powder, salt, and pepper and simmer over low heat for 5 minutes. Add additional salt and pepper to taste. Remove from heat and set aside.

To make biscuits:
Preheat oven to 325° F.

In food chopper or processor, pulse shredded cheese to finer, granular consistency.

Pour cheese into large bowl, then add almond meal, coconut flour, baking soda, and salt and mix thoroughly. Add the eggs and butter or oil and mix thoroughly to yield thick dough.

Spoon out dough into 10 or so ¾-inch thick mounds onto a parchment paper-lined baking pan. Bake for 20 minutes or until lightly browned and toothpick withdraws dry.

Ladle gravy onto biscuits just before serving.

The Perfect Carnivore

People who carry the gene for lipoprotein(a), Lp(a), tend to be:

--Intelligent--The bell curve of IQ is shifted rightward by a substantial margin.
--Athletic--With unusual capacity for long-endurance effort, thus the many marathoners, triathletes, and long-distance bikers with Lp(a).
--Tolerant to dehydration
--Tolerant to starvation
--Resistant to tropical infections

In other words, people with Lp(a) have an evolutionary survival advantage. More than other people, they make clever, capable hunters who can run for hours to chase down prey, not requiring food or water, and less likely to succumb to the infections of the wild. In a primitive setting, people with Lp(a) are survivors. Evolution has likely served to select Lp(a) people for their superior survival characteristics.

But wait a minute: Isn't Lp(a) a risk for heart attack and stroke? Don't we call Lp(a) "the most aggressive known cause for heart disease and stroke that nobody gives a damn about"?

Yes. So what allows this evolutionary advantage for survival to become a survival disadvantage?

Carbohydrates, especially those from grains and sugars. Let me explain.

More so than other people, Lp(a) people express the small LDL pattern readily when they consume carbohydrates such as those from "healthy whole grains." Recall that the gene for Lp(a) is really the gene for apoprotein(a), the protein that, once produced by the liver and released into the bloodstream, binds to an available LDL particle to create the combination Lp(a) molecule. If the LDL particle component of Lp(a) is small, it confers greater atherogenicity (greater plaque-causing potential). Thus, carbohydrate consumption makes Lp(a) a more aggressive cause for atherosclerotic plaque. The situation can be made worse by exposure to vegetable oils, such as those from sunflower or corn, which increases production of apo(a).

Also, more than other people, Lp(a) people tend to show diabetic tendencies with consumption of carbohydrates. Eat "healthy whole grains," for instance, or if a marathoner carb-loads, he/she will show diabetic-range blood sugars. I have seen long-distance runners or triathletes, for instance, have a 6 ounce container of sugary yogurt and have blood sugars of 200 mg/dl or higher. The extreme exercise provides no protection from the diabetic potential.

Because carbohydrates are so destructive to the Lp(a) type, it means that people with this pattern do best by 1) absolutely minimizing exposure to carbohydrates and vegetable oils, ideally grain-free and sugar-free, and 2) rely on a diet rich in fats and proteins.

The perfect diet for the Lp(a) type? It would be a diet of feasting on the spoils of the hunt, devouring the wild boar captured and slaughtered and eating the snout, hindquarters, spleen, kidneys, heart, and bone marrow, then eating mushrooms, leaves, nuts, coconut, berries, small rodents, reptiles, fish, birds, and insects when the hunt is unproductive.

Capable hunter, survivor, consumer of muscle and organ meats: I call people with Lp(a) "The Perfect Carnivores."

Track Your Plaque in the news

The NPR Health Blog contacted me, as they were interested in learning more about health strategies and tools that are being used by individuals without their doctors. The Track Your Plaque website and program came up in their quest, as it is the only program available for self-empowerment in heart disease.

Several Track Your Plaque Members spoke up to add their insights. The full text of the article can be viewed here.

How's Your Cholesterol? The Crowd Wants To Know
Mainstream medicine isn't in favor of self-analysis, or seeking advice from non-professionals, of course. And anyone who does so is running a risk.

But there are folks who want to change the course of their heart health with a combination of professional and peer support. Some are bent on tackling the plaque that forms in arteries that can lead to heart disease. They gather online at Track Your Plaque, or "TYP" to the initiates.

"We test, test, test ... and basically experiment on ourselves and have through trial and error came up with the TYP program, which is tailored to the individual," Patrick Theut, a veteran of the site who tells Shots he has watched his plaque slow, stop and regress.

The site was created in 2004 by Bill Davis, a preventive cardiologist in Milwaukee, Wisc. Davis is also the author of Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health, which argues that wheat is addictive and bad for most people's health. Davis recommends eliminating wheat from the diet to most new members of Track Your Plaque.

"The heart is one of the hardest things to self-manage but when you let people take the reins of control, you get far better results and far fewer catastrophes like heart attacks," Davis tells Shots.

Doctors typically give patients diagnosed with heart disease two options: take cholesterol-lowering statin drugs, or make lifestyle changes, like diet. It's usually far easier for both parties — the doctor and the patient — to go with the drugs than manage the much more difficult lifestyle changes, Davis says.

"Doctors say take the Lipitor, cut the fat and call me if you have chest pain," he explains. "But that's an awful way to manage care."

TYP has members submit their scores from heart CT scans, cholesterol values, lipoproteins and other heart health factors to a panel of doctors, nutritionists and exercise specialists. Then they receive advice in the form of an individualized plaque-control program. But the online forum, where users share their results with other members and exchange tips, is where most of the TYP action happens.

The community currently has about 2,400 members who pay $39.95 for a quarterly membership, or $89.75 for a yearly membership. Davis says all proceeds go towards maintaining the website.

Ilaine Upton is a 60-year-old bankruptcy lawyer from Fairfax, Va., and a TYP member. At a friend's suggestion, Upton decided to get a heart CT scan in July. Her score was higher than it should have been (22 instead of 0), so she decided to get her blood lipids and cholesterol tested, too, and sent a sample off to MyMedLabs.com.

She learned that her LDL particle count was over 2,000 ("crazy high," she says), and she posted her results on TYP. Davis advised her that a low-carb diet would reduce it, so she decided to try it.

Since July, she says she has had "excellent results" with the program, and her LDL counts are coming down.

"It would be nice to have a [personal] physician involved in this, but [my insurer] Blue Cross won't pay if you are not symptomatic, and I am trying to prevent becoming symptomatic," says Upton. "I feel very empowered by this knowledge and the ability to take better control of my health by getting feedback on the decisions I make."

Pecan Streusel Coffee Cake


This is about as decadent as it gets around here!

Here’s a recreation of an old-fashioned coffee cake, a version with a delicious chewy-crunchy streusel topping.

I’ve specified xylitol as the sweetener in the topping, as it is the most compatible sweetener for the streusel “crumb” effect and browning.

Variations are easy. For example, for an apple pecan coffee cake, add a layer of finely-chopped or sliced apples to the cake batter and topping.

Additional potential carbohydrate exposure comes from the garbanzo bean flour and molasses. However, distributed into 10 slices, each slice provides 7.2 grams “net” carbs (total carbs minus fiber), a perfectly tolerable amount. Be careful not to exceed two slices!

Yield 10 slices

Cake:
2½ cups almond flour
½ cup garbanzo bean flour
1 tablespoon ground cinnamon
1 teaspoon baking soda
Sweetener equivalent to ¾ cup sugar
Dash sea salt

3 eggs separated
3/8 teaspoon cream of tartar
1 tablespoon vanilla extract
4 ounces butter, melted
Juice of ½ lemon

Topping:
½ cup almond flour
¼ cup pecans, finely chopped
1 tablespoon ground cinnamon
½ cup xylitol
1 tablespoon molasses
6 ounces butter, cut into ½-inch widths, at room temperature

Preheat oven to 325º F. Grease bread pan.

In bowl, combine almond flour, garbanzo flour, cinnamon, baking soda, sweetener, salt, and mix.

In small bowl, whip egg whites and cream of tartar until stiff peaks form. At low speed, blend in egg yolks, vanilla, melted butter, and lemon juice.

Pour liquid mixture into almond mixture and mix thoroughly. Pour into microwave-safe bread pan and microwave on high for 3 minutes. Remove and set aside.

To make topping, combine almond flour, pecans, cinnamon, xylitol, and molasses in small bowl and mix. Mix in butter

Spread topping on cake. Bake for 20 minutes or until toothpick withdraws dry.

Recipe: Peanut Butter and Jelly Macaroons



If you miss peanut butter and jelly sandwiches, you’re going to absolutely love these peanut butter and jelly macaroons!

Not everybody loves the taste or texture of coconut. This issue is solved by the first step: toasting shredded coconut, then reducing them down to a granular consistency. This yields a macaroon consistency without the dominant coconut taste, replaced instead with the flavors of PB & J.

I’ve specified liquid stevia as the sweetener, but this is easily replaced by your choice of sweetener. Note that, regardless of which sweetener used, they vary in sweetness from brand to brand and the quantity required to equal the ½ cup of sugar equivalent can vary. It always helps to taste your batter and adjust sweetness.

Also, I used Swerve in this recipe, the erythritol-inulin mix that enhances texture, but its use is optional.

As written, each macaroon contains just over 3 grams “net” carbohydrates (total carbs minus fiber), meaning you can have several before doing any damage!

Makes 24 macaroons

3 cups shredded unsweetened coconut
2 tablespoons vanilla extract
1 teaspoon almond extract
¼ cup coconut flour
¼ cup dried unsweetened cherries (or other unsweetened berries)
2 tablespoons coconut oil
¼ cup natural peanut butter, room temperature
2 egg whites
½ teaspoon liquid stevia or sweetener equivalent to ½ cup sugar
2 tablespoons Swerve


Preheat oven to 300° F.

In large bowl, combine coconut, vanilla and almond extracts, and mix.

Spread mixture on baking sheet and bake for 10 minutes, stirring occasionally, until very lightly browned. Be careful not to burn. Remove and cool. (Leave oven at 300° F.)

When cooled, using food chopper, food processor, or coffee grinder, pulse coconut mixture until coconut reduced to consistency of coffee grounds. Pour back into bowl. Stir in coconut flour.

Place cherries or other berries in food chopper, food processor, or coffee grinder and pulse until reduced to small granules or paste. Remove with spatula and add to coconut mixture. Set aside.

Place egg whites in bowl and whip until frothy and stiff peaks form.

In small microwave-safe bowl, combine coconut oil and peanut butter and microwave in 10-second increments until warm (not hot) liquid. Stir in egg whites, followed by stevia and Swerve, and blend thoroughly.

Dispense dough onto a parchment paper-lined baking sheet using a 1 ½-inch cookie scooper or spoons.

Bake for 15 minutes or until lightly browned.

I Wish I Had Lipoprotein(a)!

Why would I say such a thing? Well, a number of reasons. People with lipoprotein(a), or Lp(a), are, with only occasional exceptions:

--Very intelligent. I know many people with this genetic pattern with IQs of 130, 140, even 160+.
--Good at math--This is true more for the male expression of the pattern, only occasionally female. It means that men with Lp(a) gravitate towards careers in math, accounting, financial analysis, physics, and engineering.
--Athletic--Many are marathon runners, triathletes, long-distance bicyclists, and other endurance athletes. I tell my patients that, if they want to meet other people with Lp(a), go to a triathlon.
--Poor at hydrating. People with Lp(a) have a defective thirst mechanism and often go for many hours without drinking water. This is why many Lp(a) people experience the pain of kidney stones: Prolonged and repeated dehydration causes crystals to form in the kidneys, leading to stone formation over time.
--Tolerant to dehydration--Related to the previous item, people with Lp(a) can go for extended periods without even thinking about water.
--Tolerant to periods of food deprivation or starvation--More so than other people, those with Lp(a) are uncommonly tolerant to days without food, as would occur in a wild setting.


In short, people with Lp(a) are intelligent, athletic, with many other favorable characteristics that provide a survival advantage . . . in a primitive world.

So when did Lp(a) become a problem? When an individual with Lp(a) is exposed to carbohydrates, especially those from grains. When an evolutionarily-advantaged Lp(a) individual is exposed to carbohydrates, more than other people they develop:

--Excess quantities of small LDL particles--Recall that Lp(a) is a two-part molecule. One part: an apo(a) made by the liver. 2nd part: an LDL particle. When the LDL particle within the Lp(a) molecule is small, its overall behavior is worse or more atherogenic (plaque-causing).
--Hyperglycemia/hyperinsulinemia--which then leads to diabetes. Unlike non-Lp(a) people, these phenomena can develop with far less visceral fat. A Lp(a) male, for instance, standing 5 ft 10 inches tall and weighing 150 pounds, can have as much insulin resistance/hyperglycemia as a non-Lp(a) male of similar height weighing 50+ pounds more.

Key to gaining control over Lp(a) is strict carbohydrate limitation. Another way to look at this is to say that Lp(a) people do best with unlimited fat and protein intake.

What WERE they thinking

When the Dietary Guidelines for Americans were drafted and the USDA and U.S. Department of Health and Human Services charged with disseminating this information to us . . .

When the American Heart Association created its Total Lifestyle Change (TLC) diet to reduce cardiovascular risk and reduce cholesterol . . .

When the American Diabetes Association developed its diet to help diabetics manage their blood sugars and prevent hypoglycemia . . .


How did conditions like Familial Hypertriglyceridemia fit into this scheme?

Green Tea Ginger Orange Bread

How about all the health benefits of green tea in wheat-free bread form, spiced up with the magical combined flavors of ginger and orange?

Frequent consumption of green tea accelerates loss of visceral (“wheat belly”) fat, increases HDL and reduces triglycerides, reduces blood pressure, and may provide cardiovascular benefits that go beyond these markers such as reduction of oxidative stress. In this Green Tea Ginger Orange Bread, we don’t just drink the tea—we eat it! This provides an even more powerful dose of the green tea catechins believed to be responsible for the health benefits of green tea.

You can grind your own green tea from dried bulk leaves or it can be purchased pre-ground. I’ve used sencha and matcha green tea varieties with good results. The Teavana tea store sells a Sencha preground green tea that works well. If starting with bulk tea leaves, pulse in your food chopper, food processor, or coffee grinder (cleaned thoroughly first!) to generate green tea powder. You will need only a bit, as a little goes a long way.

The entire loaf contains 26 grams “net” carbohydrates; if cut into 10 slices, each slice therefore yields 2.6 grams net carbs, a perfectly tolerable amount.


Bread:
1¼ cup almond meal/flour
½ cup coconut flour
2 tablespoons ground golden flaxseed
1 teaspoon baking powder
Sweetener equivalent to 1 cup sugar
1 tablespoon ground green tea
1½ teaspoons ground ginger
1½ teaspoons ground allspice
1½ ground cinnamon
2 large eggs, separated
¼ teaspoon cream of tartar
1 tablespoon vanilla extract
1 teaspoon almond extract
Grated zest from 1 orange + 2 tablespoons squeezed juice
1/2 cup coconut milk

Frosting:
4 ounces cream cheese, room temperature
1 teaspoon fresh lemon juice
Sweetener equivalent to 1 tablespoon sugar

Preheat oven to 350° F. Grease a 9” x 5” bread pan.

In large bowl, combine almond meal/flour, coconut flour, flaxseed, baking powder, sweetener, green tea, ginger, allspice, and cinnamon and mix.

In small bowl, whip egg whites and cream of tartar until stiff peaks form. At low mixer speed, blend in egg yolks, vanilla extract, almond extract, orange zest and juice, and coconut milk.

Pour egg mixture into almond meal/flour mixture and mix by hand thoroughly.

Pour dough into bread pan and place in oven. Bake for 40 minutes or until toothpick withdraws dry. Remove and cool.

For frosting, combine cream cheese, lemon juice, and sweetener and mix. When cooled, spread frosting over top of bread.

Chocolate Bomb Bars

These healthy bars will blast you with chocolate from several directions!

Look for cacao nibs in health food stores, Whole Foods Market, or at nuts.com. If unavailable, the bars are still delicious without them.



These bars contain around 4-5 grams "net" carbs per bar, well within the tolerance for most people.

Yields approximately 10 bars

1 cup ground almonds
2 tablespoons coconut flour
1 tablespoon unsweetened cocoa powder
1/2 cup cacao nibs
1/2 cup unsweetened shredded coconut
2 ounces 85-90% cocoa chocolate, finely chopped
3/4 cup raw pumpkin or sunflower seeds
Sweetener equivalent to 3/4 cup sugar
2 tablespoons almond butter
1/4 cup coconut milk
2 tablespoons coconut oil or cocoa butter (food grade)

Preheat oven to 200 degrees F. Lay sheet of parchment paper on large baking pan.

In large bowl, combine ground almonds, coconut flour, cocoa powder, cacao nibs, coconut, chocolate bits, pumpkin seeds, and sweetener (if dry) and mix.

In microwave-safe bowl or in small sauce pan, add almond butter, coconut milk, and coconut oil and sweetener (if liquid) and heat for 15 second increments in microwave until liquid, but not hot. If using stove, heat at low-heat enough to make liquid easily mixed, but not hot.

Pour liquid into dry almond mixture and mix together thoroughly. If too stiff, add water one tablespoon at at time until the consistency of thick dough.

Spoon out approximately 1 1/2-inch balls, shaping with the spoon and/or your hands into bar shapes.

Bake for 35 minutes. Remove and cool.

An iodine primer

What if your diet is perfect--no wheat, no junk carbohydrates like that from corn or sugars, you are physically active--yet you fail to lose weight? Or you hit a plateau after an initial loss?

First think iodine.

Iodine is an essential nutrient. It is no more optional than, say, celebrating your wedding anniversary or obtaining vitamin C. If you forget to do something nice for your wife on your wedding anniversary, I would fear for your life. If you develop open sores all over your body and your joints fall apart, you could undergo extensive plastic surgery reconstruction and joint replacement . . . or you could just treat the scurvy causing it from lack of vitamin C.

Likewise iodine: If you have an iodine deficiency, you experience lower thyroid hormone production, since T3 and T4 thyroid hormones require iodine (the "3" and "4" refer to the number of iodine atoms per thyroid hormone molecule). This leads to lower energy (since the thyroid controls metabolic rate), cold hands and feet (since the thyroid is thermoregulatory, i.e., temperature regulating), and failed weight loss. So iodine deficiency is one of the items on the list of issues to consider if you eliminate wheat with its appetite-stimulating opiate, gliadin, and high-glycemic carbohydrate, amylopectin A, and limit other carbohydrates, yet still fail to lose weight. A perfect diet will not fully overcome the metabolism-limiting effects of an underactive thyroid.

Given sufficient time, an enlarged thyroid gland, or goiter, develops, signaling longstanding iodine deficiency. (The treatment? Iodine, of course, not thyroid removal, as many endocrinologists advocate.) Your risk for heart attack, by the way, in the presence of a goiter is increased several-fold. Goiters are becoming increasingly common and I see several each week in my office.

Iodine is found in the ocean and thereby anything that comes from the ocean, such as seafood and seaweed. Iodine also leaches into the soil but only does so coastally. It means that crops and livestock grown along the coasts have some quantity of iodine. Humans hunting and foraging along the coast will be sufficient in iodine, while populations migrating inland will not.

It also means that foods grown inland do not have iodine. This odd distribution for us land dwelling primates means that goiters are exceptionally common unless iodine is supplemented. Up to 25% of the population can develop goiters without iodine supplementation, a larger percentage experiencing lesser degrees of iodine deficiency without goiter.

In 1924, the FDA became aware of the studies that linked goiters to lack of iodine, reversed with iodine supplementation. That's why they passed a regulation encouraging salt manufacturers to add iodine, thought to be an easy and effective means for an uneducated, rural populace to obtain this essential nutrient. Their message: "Use more iodized salt. Keep your family goiter free!" That was actually the slogan on the Morton's iodized salt label, too.

It worked. The rampant goiters of the first half of the 20th century disappeared. Iodized salt was declared an incredible public health success story. Use more salt, use more salt.

You know the rest. Overuse of salt led to other issues, such as hypertension in genetically susceptible people, water retention, and other conditions of sodium overexposure. The FDA then advises Americans to slash their intake of sodium and salt . . . but make no mention of iodine.

So what recurs? Iodine deficiency and goiters. Sure, you eat seafood once or twice per week, maybe even have the nori (sheet seaweed) on your sushi once in a while . . . but that won't do it for most. Maybe you even sneak some iodized salt into your diet, but occasional use is insufficient, especially since the canister of iodized salt only contains iodine for around 4 weeks, given iodine's volatile nature. (Iodized salt did work when everybody in the house salted their food liberally and Mom had to buy a new canister every few weeks.)

Iodine deficiency is common and increasing in prevalence, given the widespread avoidance of iodized salt. So what happens when you become iodine deficient? Here's a partial list:

--Weight loss is stalled or you gain weight despite your efforts.
--Heart disease risk is escalated
--Total and LDL cholesterol and triglyceride values increase
--Risk of fibrocystic breast disease and possibly breast cancer increase (breast tissue concentrates iodine)
--Gingivitis and poor oral health increase (salivary glands concentrate iodine)

(Naturopathic doctor Lyn Patrick, ND, has written a very nice summary available here.)

So how do you ensure that you obtain sufficient iodine every day? You could, of course, eat something from the ocean every day, such as coastal populations such as the Japanese do. Or you could take an inexpensive iodine supplement. You can get iodine in a multivitamin, multimineral, or iodine drops, tablets, or capsules.

What is the dose? Here's where we get very iffy. We know that the Recommended Daily Allowance (RDA), the intake to not have a goiter, is 150 mcg per day for adults (220 mcg for pregnant females, 290 mcg for lactating females). Most supplements therefore contain this quantity.

But what if our question is what is the quantity of iodine required for ideal thyroid function and overall health? Ah, that's where the data are sketchy. We know, for instance, that the Japanese obtain somewhere between 3,500 and 13,000 mcg per day (varying widely due to different habits and locations). Are they healthier than us? Yes, quite a bit healthier, though there may be other effects to account for this, such as a culture of less sweet foods and more salty, less wheat consumption, etc. There are advocates in the U.S., such as Dr. David Brownstein in Michigan, who argues that some people benefit by taking doses in the 30,000 to 50,000 mcg per day range (monitored with urinary iodine levels).

As is often the case with nutrients, we lack data to help us decide where the truly ideal level of intake lies. So I have been using and advocating intakes of 500 to 1000 mcg per day from iodine capsules, tablets, or drops. A very easy way to get this dose of iodine is in the form of kelp tablets, i.e., dried seaweed, essentially mimicking the natural means of intake that also provides iodine in all its varied forms (iodide, sodium iodate, potassium iodide, potassium iodate, iodinated proteins, etc.) This has worked out well with no ill effects.

The only concern with iodine is in people with Hashimoto's thyroiditis or (rarely) an overactive thyroid nodule. Anyone with these conditions should only undertake iodine replacement carefully and under supervision (monitoring thyroid hormone levels).

Iodine is inexpensive, safe, and essential to health and weight management. If it were a drug, it would enjoy repeated expensive marketing and a price tag around $150 per month. But it is an essential nutrient that enjoys none of the attention-getting advantages of drugs, and therefore is unlikely to be mentioned by your doctor, yet carries great advantage for helping to maintain overall health.
10,000 units of vitamin D

10,000 units of vitamin D

Joanne started with a 25-hydroxy vitamin D level of 23 ng/ml--severe deficiency.

What made this starting value even worse was that it was drawn in August after a moderately sunny summer spent outdoors. (Last summer, not this summer.) It therefore represented her high for the year, since vitamin D levels trend lower as fall and winter set in. This suggests that her winter level was likely in the teens or even single digits. In addition, note that, at age 43, Joanne has lost much of her ability to activate vitamin D in the skin.

So I advised that she take 6000 units of an oil-based gelcap per day, a dose likely to generate the desired blood level, which I believe is 60-70 ng/ml.

Four months later, her 25-hydroxy vitamin D level: 39.9 ng/ml--still too low. So I advised her to increase her dose to 10,000 units per day. Several months later, her 25-hydroxy vitamin D level: 63.8 ng/ml--perfect.

However, on hearing that she was taking 10,000 units vitamin D per day, Joanne's primary care physician was shocked: "What? Stop that immediately! You're taking a toxic dose!" So Joanne called me to find out if this was true.

No, of course it's not true. It's not the dose that's toxic, but the blood level it generates. Although it varies, vitamin D toxicity, as evidenced by increased blood calcium levels, generally does not even begin to get underway until at least 120-130 ng/ml, perhaps higher. Rarely, a dose of 2000 units per day will generate a level this high. In others, it may require 24,000 or more units per day to generate such a high level.

So it's not the dose that's toxic, but the blood level of 25-hydroxy vitamin D it generates.

Provided you and/or your doctor are monitoring 25-hydroxy vitamin D blood levels, the dose is immaterial. It's the blood level you're interested in.

Comments (47) -

  • Pater_Fortunatos

    8/2/2010 8:06:19 PM |

    There is a romanian guy that promotes healthy life style with low carb and other paleo ideas.

    http://www.cristianmargarit.ro/

    On his forum, a schizo girl was asking about suplemments, but she was really amazed by Dr Davis prescriptions, 6000 UI/zi, she said that NowFoods recomand a 5000 UI gelcap /3 days.

    But Cristian (the body builder from the link) replies:

    "It happened that I had once 100.000 UI on a day of vitamin D. Yes, one hundred thousands! When you try to adjust the level for certain deficencies, the therapeuthical doses can be a lot higher than the usual doses, that look like jokes for healthy people."

    Readind the article that Dr Davis just published, I assume he has a point, but 100.000 on a day!?!

  • Anonymous

    8/2/2010 8:16:33 PM |

    hi Dr. Davis

    could you sum up the benefits of vitamin d for non heart patients?

    im in early twenties and have my vit d at 18!

    i feel normal. what can i expect with higher blood levels of this vitamin?

    i have some source naturals 2000 ui powdered caps is that effective?

    Thanks

  • enliteneer

    8/2/2010 8:49:12 PM |

    There is evidence to suggest a correlation between high circulating Vitamin D blood levels (>40ng/ml) and rare cancers (pancreatic, etc):

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892544/?tool=pmcentrez&report=abstract

    http://cancerres.aacrjournals.org/cgi/content/full/66/20/9802

    http://cancerres.aacrjournals.org/cgi/content/abstract/69/4/1439

    http://aje.oxfordjournals.org/cgi/content/abstract/kwq114

  • Anonymous

    8/2/2010 9:05:48 PM |

    My Vit. D level 2 years ago was 42, I started supplementing with 6K per day.  I retested this spring and had decreased to 41.  

    I was amazed and confused.

    After some communications with the Vit. D council,  I found out that the Tretinoin Cream I was using for my splotching skin was interfering with absorption of Vit. D.

    I have since stopped the cream, increased to 12K per day and get 1 hour of sun without any sunscreen.
    I am sure my Dermatologist won't be happy with my tan.

  • aurelia

    8/2/2010 11:22:05 PM |

    Did you call her PCP?

  • steve

    8/3/2010 12:54:59 AM |

    2 questions about vitamin d. Should I take it in the summer months. I work outside all day long? Whats the differences between vitamin d with cod liver oil  and without ? thanks...

  • Tommy

    8/3/2010 1:11:35 AM |

    What about taking Vitamin A to counter balance Vitamin D?

  • Patricia Dillavou

    8/3/2010 3:45:24 AM |

    It has been determined that toxicity concerns for VD3 occur somewhere around 200 ng/ml.  (www.grassrootshealth.net)

    Vitamin D experts recommend between 70-90 ng/ml depending on the doctor.  Some even higher. For instance - Dr. Cannell of The Vitamin D Council (www.vitamindcouncil.org) recommends at least 90-100 ng/ml for cancer survivors.

    Dr. Cannell is also on the board of GRH - both non-profit advocacy groups promoting the health benefits of VD3.

    Grassroots Health is running a five year study on VD3 that is well worth joining.  Anyone can join - find the details at their website.

  • Patricia Dillavou

    8/3/2010 3:54:18 AM |

    Dr. Cannell warns that vitamin A "antagonizes the action" of VD3.  He says you don't need to supplement with vitamin A outside of a good diet.

    Not quite halfway down in this newsletter post:
    http://www.vitamindcouncil.org/newsletter/2008-june.shtml

  • Sara

    8/3/2010 4:07:00 AM |

    I read a study recently where they measured the actual amount of vit. D present in various name brands. They varied in strength from 1% to 82%.
    That's very weak on the mfgs. part and would only encourage the use of prescription D.
    Here is the link:
    http://www.medpagetoday.com/MeetingCoverage/CMSC-ACTRIMS/20522

  • Pat D.

    8/3/2010 4:08:36 AM |

    Enliteener - a quote from the study at the second link you provide:
    ( 7). Ecologic data are not supportive of a strong positive association between vitamin D and pancreatic cancer as sunnier regions do not have higher rates of pancreatic cancer. In fact, the opposite is true, in the United States, relatively high pancreatic cancer rates are observed in states where UV exposure is low.

  • vlado2020

    8/3/2010 11:46:08 AM |

    as much I respect dr. Davis he is like all the docs obsessed with numbers and stability and "safety". Unfortunatelly it ignores the basic properties of vitamin D which is an essential , perhaps most important hormone in all the living beings. First of all , vitamin D gets activated in kidneys first and if kidneys get saturated in tissues where all the healing properties of vitamin D occur. Second of all , there is a reason why oral supplementation is possible throughout life as opposed to simple skin synthesis. Then our bodies can absorb much more orally at once than through the skin which leads me to believe that we are designed to take much larger doses at once to correct deficiencies. Lastly vitamin D is fat soluble so it stays with you for 2 months at least. Having said all that , it doesn't make any sense to supplement every day with lesser doses than you can synthesize in the skin or to follow some magical numbers.
    I have dealt with a very stubborn case of psoriasis for 3 years but in a few days I am taking a big vitamin D experiment, 30 days / 500 000 IU daily, 15 million in a month. Indeed if you search google archives you can find newspaper clippings from 30's and 40's when doctors were more liberal and less obsessed with money of such doses reversing psoriasis and arthritis and other auto immune conditions.

  • MissPkm

    8/3/2010 2:16:13 PM |

    Dr Davis, A great post yet again. I guess that is the one single line I have forgotten to tell people "it is not the dose, it is the blood level that matter"!! GREAT! Thank you.

    Sara,
    There is a big concern for supplements on the market as they are not being checked by any agencies, and just like Dr Davis previous have been reporting on - some Vitamin D3 over the counter are not what they say they are. However in this study that you refer to (the part that I was able to read) they do not list the name brands or the type of Vitamin D (pill, gel cap, liquid) as that also plays a big role. I think it is a big separation from the message in the report of saying to only take Vitamin D2 (which is the prescription vitamin D) when we know D2 is not natural to us humans nor is it better. I suggest you read a little bit more about D2 and D3 before deciding what is best for you.

  • Ned Kock

    8/3/2010 5:00:11 PM |

    Hello Dr. Davis.

    Let me point out a few things based on research on vitamin D. Not all agree with what you said in your post, but then again you may well be right and the research wrong:

    - Indeed, toxicity signs do not seem to occur until one reaches the 50,000 IU/d level of intake.

    - Among the elderly (i.e., those aged 65 or above) pre-sunburn full-body exposure to sunlight is equivalent to an oral vitamin D intake of 218 µg (8,700 IU). That is close to 90 percent of what a 20-year-old would produce.

    - People on average will plateau at 130 nmol/L, after months of 10,000 IU/d supplementation. That is 52 ng/mL. Assuming a normal distribution with a standard deviation of about 20 percent the peak mean (a rough guesstimate), one would expect 68 percent of the population to be in the 42 to 63 ng/mL range. That might be the range most of us should expect to be in at an intake of 10,000 IU/d.

    As we know, some people are outliers. A person who is two standard deviations above the mean would be at around 73 ng/mL. Three SDs above the mean would be 83 ng/mL. These are outliers; non-average people.

    There are other factors that may have affected the results for this patient. Being overweight tends to reduce D levels. Sunscreen also does that. Excess cortisol may also be affecting D levels.

    Below are two links with more details:

    http://healthcorrelator.blogspot.com/2010/02/vitamin-d-levels-sunlight-age-and.html

    http://healthcorrelator.blogspot.com/2010/01/vitamin-d-deficiency-seasonal.html

  • stop smoking help

    8/3/2010 6:56:15 PM |

    I wonder what levels are found in smokers? I know smokers aren't supposed to supplement with beta-carotene as it statistically increases their risk of developing lung cancer.

    What about vitamin D? Is there any data on this as it relates to people who smoke cigarettes or other tobacco products?

  • Anonymous

    8/3/2010 9:57:45 PM |

    This is so off topic, but for some reason I cannot find the Pharmax website for fish oil. Can anyone help?  Thank you
    From an old person who is not tech savvy.

  • Matthew

    8/3/2010 11:01:03 PM |

    There is a graph of vitamin D blood levels on the video by Dr. Michael Holl+
    ick that shows the knee of the runaway blood levels is around 10,000 IU per day, and he recommends no more than that on an ongoing basis.

    For me, 5000 iu per day stopped my gums from bleeding when I brushed, and ended decades of dysthymia.

    http://www.youtube.com/watch?v=Cq1t9WqOD-0
    http://www.uvadvantage.org/

  • Anonymous

    8/5/2010 6:21:19 PM |

    Dr Davis,
    You are absolutely right that "it is not the dose, it is the blood level that matters”. But, what about the blood level of calcium? One of the causes of the toxicity of Vit D is that it may cause high calcium levels in blood. So, should we not measure also the calcium level, and if it is high then should we not stop taking D, even though  its blood level may be normal or low? Thank you.

  • Ganesh

    8/6/2010 8:17:05 AM |

    How does a dosage of Vitamin D3 supplementation totaling 2,260,000 IU over 56 days averaging daily to about 40,000 IU sound?? Resulting in a blood level of 239.0 ng/mL?? This is no fiction...but my personal experience...and I have never felt more better since then! I got rid of my pre-diabetes, Metabolic Syndrome and other fancy new-age potential diseases...  Read all about it at gkwellness.wordpress.com.

  • TedHutchinson

    8/6/2010 9:16:15 AM |

    Perhaps it would be well for others to read what Dr Cannell has to say about massive doses of vitamin D.

    Warning: If you intend to take massive doses of vitamin D based on this newsletter, which I highly recommend you do not, read the entire newsletter. In addition, accurate determination of side effects of massive doses of vitamin D was not available in the early 1930s, nor was accurate determination of the true amount in each pill possible.

    You'll find the Vitamin D Council newsletter at this link.
    Gary Null and Vitamin D Toxicity

  • Josh

    8/6/2010 12:44:21 PM |

    I've been taking 10,000 IUs a day for the last 3 months.  Got my results back today:  I went from 51ng/dL to 65 ng/dL.  I eat strictly paleo and I also get regular sun.  I expected a greater increase.  I also had a CMP run to check for hypercalcemia - all good.

  • Anonymous

    8/7/2010 1:03:50 AM |

    I recently went to a doctor for pre-diabetes and high cholestrol and found my vitamin d level is 17 and I am breastfeeding. Does anyone know what a safe amount would be for me to take. I am taking 5000 d3, liquid dropper full. I am very tan, and out in the sun...why am I not absorbing or making the hormone? My crp level was 24, they said that wasn;t normal. Could this be a effect of this wheat allergy I am reading about? What do you think Dr. Davis?

  • Jimmy Moore

    8/7/2010 11:12:16 AM |

    I too got the same reaction from my doctor when I told him I take 10,000IU daily.  But I HAVE to in order to reach that optimal level you're talking about.  Two years ago my D3 was 42, so I went on a 6-month Vitamin D3 gelcaps regimen to get it up to 68.  Wanting to find the balance of how much to take, I backed off to 6,000IU for about 8 months and my D3 level dropped back down to 50.  So I've been on 10,000IU daily again for the past 8 months and look forward to seeing my levels return into the 60s where they need to be.  THANK YOU Dr. Davis for leading the way on this important issue.  My wife Christine had a D3 level of 9 before starting 10,000IU herself--today her D3 is 54 and she's completely off of her Paxil medicine.  WOO HOO!

  • Anonymous

    8/8/2010 6:57:56 PM |

    I can't find the link but I recall reading something, possibly by Dr. Cannell urging people who are taking higher quantities of vitamin D to ALSO take extra Magnesium and Potassium to prevent kidney stones(which may occur with higher dosing of Vitamin D).

    If this is the case, how much mag and potassium should one take to prevent stones?

  • Neonomide

    8/11/2010 9:58:48 PM |

    Vitamin D3 decreased relapse rate by 50% in Crohn's disease patients in a 12 month randomized controlled trial:

    http://www.ncbi.nlm.nih.gov/pubmed/20491740


    I knew this for almost two years already and got to ditch my meds, just by taking enough Vitamin D3. If everything in healthcare was this simple we would not have major healthcare problems, yes ?

  • mike V

    8/21/2010 4:56:17 PM |

    Dr D.
    It has probably by now come to your attention that there is some evidence for a U shaped mortality curve with vitamin D in elderly men, esp cancer.

    Here is one report:
    *Plasma vitamin D and mortality in older men: a community-based prospective cohort study.*

    Michaëlsson K, Baron JA, Snellman G, Gedeborg R, Byberg L, Sundström J, Berglund L, Arnlöv J, Hellman P, Blomhoff R, Wolk A, Garmo H, Holmberg L, Melhus H.

    Am J Clin Nutr. 2010 Aug 18. [Epub ahead of print]PMID: 20720256 [PubMed - as supplied by publisher]Related citations

    My suspicion is that it may  be related to insufficent vitamin K2, which of course may relate to typical elderly diets.

    Please comment, and/or refer us to earlier comments you may have made.
    Thank you
    Mike V

  • TedHutchinson

    8/21/2010 10:39:36 PM |

    How to Optimize Vitamin D Supplementation to Prevent Cancer, Based on Cellular Adaptation and Hydroxylase Enzymology
    At the most northerly latitudes such as Sweden, where the study Mike V linked to was done and Finland where P Tuohimaa has reported similar findings, we have to appreciate the people with the highest vitamin D status probably have the largest changes in status over the year.
    Vieth provides a hypothesis that explains how people with extreme changes in status experience longer periods of imbalance between the forces controlling cell proliferation.
    Vieth suggests keeping 25(OH)D BOTH HIGH and STABLE is the safest option that way there is little or no CHANGE in status through the year, so no periods where dis-regulation of the counterbalancing forces could occur.

  • Anonymous

    8/22/2010 11:50:44 PM |

    Ted,

    If I'm reading what you posted correctly, Vieth is indicating that one should maintain higher serum d-levels year round as opposed to allowing them fluctuate?

  • Anonymous

    8/22/2010 11:53:29 PM |

    I'm sure this has been asked before but what's a suitable dosing strategy for someone who just flat out refuses to get their 25(OH)D3 levels checked? My brother is 28, I've convinced him to start supplementing with vitamin D but her refuses to go to the doctor to get blood drawn and when I suggested he order a kit online and do it himself he looked at me like I was crazy.

    I have him on average taking 5000 to 6000 units per day.

    Mike

  • TedHutchinson

    8/23/2010 9:39:52 AM |

    @ Vieth is indicating that one should maintain higher serum d-levels year round as opposed to allowing them fluctuate?

    Vieth says so long as serum 25(OH)D concentrations are in a phase of decline, there can be no full achievement of tissue 1,25(OH)2D to match its ideal set-point concentration.

    There have been a couple of papers recently showing ANNUAL vitamin D supplementation (raising status with high intakes before winter) only makes matters worse because it creates a longer period of declining 25(OH)D.

    Note also that because Ergocalciferol has a shorter half life than D3 it amplifies this problem so should be avoided.

    Supplementing DAILY or WEEKLY reduces the potential for fluctuation so are ideal but fortnightly or even monthly supplementation with D3 probably avoid the periods of declining status, if the person concerned really isn't capable of more regular dosing.

    The amount of vitamin D made in the skin varies with 25(OH)D status This reduces the summer rise in status but if you get lots of sun in summer (unlike the UK)it may be sensible to REDUCE (but not stop) vitamin D supplements while you are also getting near full body sun exposure, and then resume the full amount of supplementation as soon as sun exposure reduces.

    I think people who live furthest from the equator have to be particularly careful when taking winter sun holidays in the tropics.
    As Vitamin D is itself photoprotective it's worth supplementing with vitamin D before a winter sun break rather than relying on the holiday sun to raise status. Then reduce intake while sunning in the tropics but resume supplementation as soon as you return. Careful supplementation increases serum 25(OH)D concentrations and reduces the effect of the seasonal amplitude in 25(OH)D on the tissue fluctuations in 1,25(OH)2D.

  • TedHutchinson

    8/23/2010 10:11:13 AM |

    @ Mike
    Grassrootshealth graph of typical responses to various vitamin D intakes

    Startling Findings About Vitamin D Levels in Life Extension® Members

    The graphs at the above links show 5000~6000iu/daily gets most people above insufficiency status and doesn't raise status above a safe amount.

    The range of response to regular D3 supplements is about 100ng/ml so without a few 25(OH)D tests it's impossible for anyone to say if you're at the lowest or highest end of that response scale.

    If you're diabetic or celiac then it's likely you're a poor responder but there are people reading this with inflammatory conditions who've taken very modest vitamin D3 amounts but had extremely high 25(OH)D test results.

    It's so simple to put a couple of drops of blood on a test strip and post if off that I'm surprised everyone doesn't get it done.

    Once you've had a few tests done you can more or less predict what the result will be, but there have been instances where people have changed brands of D3, been tested and discovered problems.

    Only if you've had a test can you be certain the brand/batch/amount/dosing regime of D3 you are taking is working for you.

  • mike V

    8/23/2010 1:30:20 PM |

    Thanks for the helpful posts, Ted.
    Is it your interpretation that variability still remains important, even if one's 25(OH)D does not fall below say 30 or 40 ng/mL over the year, or do you think the the lower excursion limit would have to drop to a deficient level at least for a part of the year? It would seem to me that storage in body fat would be a consideration in minimizing variability.
    Have you come across any studies on U curve effects  performed at lower latitudes, or perhaps on those supplementing?

    I am a vintage Brit, living in the "Deep South", and whose last readings were between 60 and 70 ng/ml so I have no personal concerns.
    Last winter I was using 8000iu, but I drop back to 4-6000 in the Summer months, when we typically have highs between 90 and 100F.
    FWIW I have been gradually escalating my dose over a period of more than 10 years. Now in 75th year.
    regards
    Mike V

  • TedHutchinson

    8/23/2010 2:01:16 PM |

    @ It would seem to me that storage in body fat would be a consideration in minimizing variability. I agree.
    Bear in mind we don't see significant stored D3 reserves below 40ng/ml but at 50~60ng/ml reserves are measurable.
    I stay around 60ng/ml with 5000iu/d + regular full body UVB/SUN exposure.
    I'm not aware of any data on Ushaped curve at lower latitudes or with people maintaining a steady state 25(OH)D by avoiding declines in 25(OH)D.
    I'd be more than willing to participate in any trial, providing I'm assured of remaining on the high end arm of the study.

  • mike V

    8/23/2010 2:56:12 PM |

    Thank you.
    One more question.
    It appears that UVB/sun exposure is useful way to 'top off' supplementation in a natural or controlled way.
    Seems we evolved our African metabolisms getting a heavy daily full body dose.

    Are you aware of any data suggesting that UVB sourced D has any other advantages over presumingly well managed supplementation?
    Thanks again
    I appreciate your awareness of, and facility at quoting relevant studies.
    Mike V

  • Anonymous

    8/23/2010 6:42:53 PM |

    Ted, you bring up an interesting point regarding different dosing methods. Here's a study comparing daily vs. weekly vs. monthly dosing of D3.

    http://jcem.endojournals.org/cgi/content/full/93/9/3430

  • Anonymous

    8/23/2010 7:28:43 PM |

    Seasonal fluctuations may be of importance but the overall 25(OH)D levels still seem most important.

    The Framingham Study data and other papers have already pointed out that not only total mortality, but also bone health seems best in about 35-40 ng/ml, not more. Similarly, not-so-rare cancers like in prostate and pancreas (kills practically everyone) may well increase in susceptiple populations ie in smokers.

    There are also racial differences that may be of huge importance. Not only CHD risk and 25(OH)D does follow the skin color pretty closely, but native Africans also have rather low 25(OH)D levels which perhaps explains the association. Even doctor Cannell wrote previously about this:

    "Dr. Freedman and his Wake forest colleagues measured vitamin D levels and plaque (the build-up in your arteries) on 340 diabetic, obese (BMI 35) African Americans and found higher vitamin D levels were associated with more plaque build up in the arteries."

    http://www.vitamindcouncil.org/newsletter/vitamin-d-race-and-cardiovascular-disease.shtml


    Infants in Nigeria have much higher 25(OH)D levels, yet as Nigerian people get older, their 25(OH)D levels drop a lot.

    I'd imagine that tremendous UVB exposure for decades makes it progressively harder to make Vitamin D and that seems to be the simplest explanation. Elderly white-skinned people may on the other hand make a lot more Vit D as a recent study shows. I'd die to know if the same works out for native Africans as well - which I very much doubt.

    Vitamin D has tens of metabolites that form only in the skin. This may be the single biggest challenge to the claim that Vitamin D supplementation fixes "everything".

    A quick googling on a wide array of problems people have had when supplementing more than 2000 IU a day is dazzling. So D3 may be a wonder vitamin, but it's benefits are dose dependent and probably highly dependent of other nutriotional factors as well, since D3 affects the absorption of minerals, expression of hundreds of genes and so on.

    Food rep

  • TedHutchinson

    8/23/2010 10:47:56 PM |

    @ you bring up an interesting point regarding different dosing methods ...Comparison of Daily, Weekly, and Monthly Vitamin D3
    Perhaps that is because I regard the natural level at which humans produce vitamin D replete breast milk, achieve 25(OH)D equilibrium and maintain a stored reserve of vitamin d3 as ideal, not the level used in that study that barely ever provides sufficient even for basic daily needs.

    Health professionals may aim for a level that maximises health service interventions. I want a level that minimises my need to use those services.

    Bankers make more money from people who frequently use overdraft and loan services. I prefer to save up, keep a reserve of cash in an instant access savings account, only every pay cash and get discounted prices.

    You may be happy to manage your Vitamin D account without ever having any spare reserves available for emergency use but IMO that is neither prudent or safe.

    Why on earth would your skin produce 10~20000iu in a relatively short time if only 1500iu were required?

  • mike V

    8/24/2010 1:39:15 AM |

    Food Rep:
    Suggest you take as a baseline levels that are thought to be closer to the equatorial 25(OH)D blood levels we evolved with. Not minimal levels to mitigate some particular symptom or disease.
      Yes, achieving this goal largely by supplements, can be complicated depending on skin color, genetics, latitude, age, body fat, but in my judgment it is well worth achieving, and it will become easier as time goes on.

    IMHO, Ted and Dr Davis have it about right.

    Do you visit www.grassrootshealth.net?
    If not I recommend you do so... soon. IMHO there is not a more authoritative resource on this topic.
    Mike V
    By the way, vitamin D does not *cause* calcification. It does enable homeostasis.

  • Anonymous

    8/24/2010 2:51:38 PM |

    Ted,

    I only posted that study above to show that different dosing schedules (daily, weekly, monthly) all seem like viable approaches in maintaining 25(OH)D3 levels granted you are consistent with it. I wasn't trying to suggest that the actual doses they were administering were adequate.

  • Anonymous

    8/25/2010 4:45:49 PM |

    I just trying to have ripped abs.  I am not taking any supplements or anything like that but the literature here suggests that taking some substances could actually have an adverse affect on your body even though they are supposed to be healthy.

  • mike V

    8/26/2010 6:29:59 PM |

    Ted, Dr D.
    I suggest that vitamin 2K should be considered in association with Vitamin D where the cancer mortality curve is in question.
    **
    http://www.lef.org/magazine/mag2009/jan2009_Vitamin-K-Protection-Against-Arterial-Calcification-Bone-Loss-Cancer-Aging_03.htm
    **
    note: I believe I am right insaying that the first 15 references cited in this article relate to cancer.
    Mike

    Mike V

  • max

    9/25/2010 7:50:35 AM |

    good article.

  • Anonymous

    10/30/2010 4:40:15 PM |

    I recently did the Vitamin D Council blood spot test. It cost $70.00 including shipping I think. It was painful and two weeks later, my finger still hurts. If I ever do another blood spot test, I'll try to draw blood from my forearm, although the test requires at least 2 large blood drops. I have no results yet. I am 114 lbs and take 2400 IU a day (softgels). I don't really plan to test ever again, especially on my finger, so I'll play it safe and keep my level around 40. Obviously, I'll have to adjust accordingly, once I get the results. I don't have the luxury of a good doctor. Doctors around here are virtually useless.

  • Anonymous

    1/21/2011 5:19:23 PM |

    Hi there,
    Been researching Vit D here on the heartscan blog and others such as Vit D counsil, Dr. Ben Kims' site,getting good info to stay away from D2 of course.
      But this site, "The Peoples Chemist"- Shane Ellison and blog poster "Chuck" say we all should stay away from any man-made D3(sheep wool) included. They back it up stating specific chemical biological changes in the body.  They say it just isn't the same and can do more harm in the long run. The site states basically that we should be using only food for Vit D3. meats, eggs, cod-liver oil(w/o the vitamins depleted or added)ect...
       This is real important for all of us if this is true.  Please Heart scan Bloggers/Dr. Davis read the info @ Vit D on Shanes site... Thanks

  • Anonymous

    1/21/2011 5:19:47 PM |

    Hi there,
    Been researching Vit D here on the heartscan blog and others such as Vit D counsil, Dr. Ben Kims' site,getting good info to stay away from D2 of course.
      But this site, "The Peoples Chemist"- Shane Ellison and blog poster "Chuck" say we all should stay away from any man-made D3(sheep wool) included. They back it up stating specific chemical biological changes in the body.  They say it just isn't the same and can do more harm in the long run. The site states basically that we should be using only food for Vit D3. meats, eggs, cod-liver oil(w/o the vitamins depleted or added)ect...
       This is real important for all of us if this is true.  Please Heart scan Bloggers/Dr. Davis read the info @ Vit D on Shanes site... Thanks

  • Lynn D

    9/20/2012 10:32:05 PM |

    If our vite D levels show up low 20every year ,even when take 4000/day, then
    are we not absorbing or are we using it up. It sounds like some websearch showed up maybe
    additional testing such as also 1,25 OH in additon to the 25OH
    Thanks for any info

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