Who lost weight?

The results of the latest Heart Scan Blog poll are in.


I went wheat-free and I . . .


Gained weight 6 (3%)

Lost no weight 41 (21%)

Lost less than 10 lbs 28 (14%)

Lost more than 10 lbs 34 (17%)

Lost more than 20 lbs 22 (11%)

Lost more than 30 lbs 28 (14%)

I'm still losing weight! 30 (15%)

(189 respondents)


This means that, by eliminating wheat:

24% had no success

31% had moderate success (less than 10 lbs or more than 10 lbs)

25% had extravagant results with 20 lbs or more lost


It would be interesting to know where along the weight-loss spectrum the last category, "I'm still losing weight," group falls. (Anyone with a good story please speak up!)

I believe we can conclude from this casual exercise that, as a simple strategy, wheat elimination is surprisingly effective.

Why would 3% gain weight? Well, without knowing the details, there are several possible explanations:

1) Weight gain developed through other foods. For instance, I've had people eliminate wheat only to replace it with fattening gluten-free alternatives. Remember: wheat-free is not gluten-free. Others load up on the wrong foods, e.g., Craisins and other dried fruit; overdo dairy; or snack on wheat-free but unhealthy foods like ice cream and chips.

2) Too much alcohol

3) Hypothyroidism--A lot more common than you'd think. In fact, this has been the case with a majority of people who have done everything right, yet either failed to lose weight or gained weight.

Those are the biggies.

I'd like to hear your personal stories of wheat elimination--the ups and downs, your success or failure, how you felt during the process, how easy or difficult, your eventual results. Just post them as a response to this blog post.

A niacin primer

A reader of Life Extension reminded me of a piece I wrote about niacin a couple of years back.

Anyone desiring a primer on how and why to use niacin to correct lipid and lipoprotein patterns might find this useful.

While some people, no matter what they do, cannot tolerate niacin (about 10% of people), many others enjoy spectacular benefits.


Q: I recently had a cholesterol profile blood test and learned that I may be at risk of heart disease because my levels of beneficial HDL (high-density lipoprotein) are too low. I read that niacin could help increase my HDL, but my doctor said niacin is dangerous. Whom should I believe?

A: Your doctor would be right—if we were still living in 1985. Since then, however, we have learned how to use niacin (vitamin B3) safely and effectively. Unfortunately, many physicians have not yet caught up, or are still trapped by the idea that cholesterol-lowering statin drugs are the only way to decrease cardiovascular disease risk. I have personally prescribed niacin for thousands of patients as part of our program to reverse coronary disease. In fact, niacin is the closest thing we have available to a perfect treatment that corrects most of the causes of coronary heart disease.

Continued here.

What would life be like . . . ?

What if coronary heart disease could be prevented--no eliminated--applying methods that were accessible, easy, and cheap?

What if coronary heart disease and, thereby, angina, heart attack, sudden cardiac death, ventricular tachycardia, heart failure, and the cerebrovascular equivalent, stroke, could be eliminated using readily available tools available to virtually everyone in the U.S.? And, over a year, it cost less than a once-a-week latte at Starbucks?

How would the healthcare landscape change? What would become of hospitals, manufacturers of the billions of dollars of hospital equipment necessary to supply the cardiovascular hospital industry (e.g., stent manufacturers, catheter manufacturers, defibrillator and pacemaker manufacturers, pharmaceutical manufacturers who no longer have to produce the volume of antiplatelet agents, inotropic drugs, antiarrhythmic agents, etc.)?

How would our lives change? What would the end of life look like if people stopped dying of heart attack, sudden cardiac death, congestive heart failure at age 55, 65, or 75, but lived out their lives to die of something unrelated?

What if the solution had little or nothing to do with drugs but evolved from simple nutritional strategies, supplements meant to correct the deficiencies that accompany modern lifestyles, and a few unique strategies targeted towards the genetic predispositions that lead to heart disease?

What if all this were possible at a cost of a few hundred dollars per year?

It would certainly be a cataclysmic change. Hospitals would shrink to a small remnant of their current gargantuan, dozens-per-city presence. The need for hospital staff would be slashed by over half. The rare cardiologist would tend to congenital heart disease sufferers and other unusual forms of heart disease and he or she might have a colleague or two in all of a major city.

Healthcare costs would plummet, no longer having to sustain the enormous cardiovascular healthcare machine of hospitals, staff, industry, and long-term care. Health insurance, private or public, would drop by 50%.

It would free up nearly a trillion dollars that could be redirected towards other pursuits, like schools and research. Extraordinary leaps forward in quality of life and science would emerge, given that magnitude of funding.

It's not as grand a thought experiment as Alan Weisman's The World Without Us, in which he imagines what the world would be like without humans altogether.

How long would it take to recover lost ground and restore Eden to the way it must have gleamed and smelled the day before Adam, or Homo habilis, appeared? Could nature ever obliterate all our traces? How would it undo our monumental cities and public works, and reduce our myriad plastics and toxic synthetics back to benign, basic elements?

But I believe this thought experiment--what would life be like without heart disease because it was eliminated using inexpensive tools-- is more plausible, more likely to occur. In fact, it has already begun to occur.

See those vines growing up the side of the hospital?

Are jelly beans heart healthy?

Total Fat

3 g or less

Less than 6.5 g





Saturated Fat



1 g or less

1 g or less





Cholesterol

20 mg or less

20 mg or less





Sodium

480 mg or less per RACC* & labeled serving

480 mg or less per RACC* & labeled serving





Nutrients

Contain 10 percent or more of the daily value of 1 of 6 nutrients; vitamin A, vitamin C, iron, calcium, protein or dietary fiber



Contain 10 percent or more of the daily value of 1of 6 nutrients; vitamin A, vitamin C, iron, calcium, protein or dietary fiber





Trans fat

Less than 0.5 g per RACC* and labeled serving



Less than 0.5 g per RACC* and labeled serving





Whole Grain

N/A



51 percent by weight/RACC*







Minimum Dietary Fiber



N/A

1.7 g/RACC of 30 g

2.5 g/RACC of 45 g

2.8 g/RACC of 50 g

3.0 g/RACC of 55 g





(RACC=Reference Amount Customarily Consumed)

Thyroid correction: The woeful prevailing standard

Rich has been taking Synthroid or levothyroxine for many years.

When Rich came to my office for continuing management 10 years after his bypass surgery, I checked his thyroid panel:

TSH 7.44 uIU/L

Free T4 1.88 ng/dl (Ref range 0.80-1.90 ng/dl)

Free T3 2.0 pg/ml (Ref range 2.3-4.2 pg/ml)


Rich's thyroid hormone distortions--high TSH, low T3--are sufficient to account for a tripling of heart attack risk long-term.

As Richs' thyroid was being managed by his primary care physician, I notified this doctor of Rich's panel. He therefore increased Rich's levothyroxine from 75 mcg per day to 100 mcg per day. Another thyroid panel several months later showed:

TSH 0.98 uIU/L

Free T4 2.38 ng/dl

Free T3 2.0 pg/ml



As you would expect, increasing the intake of the T4 hormone (levothyroxine) increased free T4 and suppressed TSH.

But what about T3? It's unchanged.

Indeed, Rich says that he feels no better and, in fact, wakes up in the morning foggy and requires a nap in the afternoon.

In my experience, the majority (approximately 70%, but not 100%) experience subjective improvement when T3 is added in some form and the free T3 level is increased. While the data (summarized here) are conflicted on whether there is objective benefit to T3 management and supplementation, there seems to be a poorly-quantified subjective improvement.

Rich's increased levothyroxine dose decreased (calculated) LDL cholesterol by 10 mg/dl. Based on my experience, I'll bet that his lipid panel would likely be further improved with T3 correction.

What I find incredible is the absolutely rabid resistance waged by primary care physicians and endocrinologists against this notion of T3, mostly due to fears of the remote likelihood of inducing atrial fibrillation and osteoporosis, while they are ready to prescribe lifelong statin drugs without a moment's hesitation.

Launch of new Track Your Plaque newsletter: Cardiac Confidential

Track Your Plaque has just launched a new version of our newsletter. We call it Cardiac Confidential.

Cardiac Confidential is meant to be a no-holds-barred, go-for-the-throat exposé of the world of heart disease. We will expose the dishonest, reveal what we view as the underlying truth. We'll even have an occasional "undercover" report of what goes on in hospitals and the go-for-the-money world of heart procedures.

Read the first issue here (open to everyone) in which "Laurie" describes her encounter with a sleazy, profiteering cardiologist. She survives, but not without paying a dear price.

Thyroid: Be a perfectionist

If you'd like to reduce LDL cholesterol with nearly as much power as a statin drug, think thyroid.

When thyroid is corrected to ideal levels, LDL cholesterol drops 20, 30, 40 mg/dl or more, depending on how poor thyroid function and how high LDL are at the start. The poorer the thyroid function (the higher the TSH or the lower the T3 and T4) and the higher the LDL cholesterol, the more LDL drops with thyroid correction.

(For those of you minding LDL particle size, such as Track Your Plaque Members, the "dominant" LDL species will drop: If you are genetic small LDL, small LDL will drop. If you have mostly large LDL because of being wheat-free and sugar-free, then large LDL will drop.)

One of the problems is that many healthcare providers blindly follow what the laboratory says is "normal" or the "reference range," which is usually nothing more than a population average (actually the mean +/- 2 standard deviations, a common method of developing references ranges). In other words, a substantial degree of low thyroid function, or hypothyroidism, can be present when your doctor adheres to the reference range provided by the laboratory.

What does it mean to achieve ideal thyroid status? My list includes:

--Normal oral temperature of 97.3 F first upon arising. (The thyroid is the body's thermoregulatory organ.)
--TSH 1.0 mIU/L or less
--Free T3 upper half "normal" range
--Free T4 upper half "normal" range
--You feel good: mental clarity, energy, upbeat mood. You lose weight when you try.

Iodine replacement should be part of any thyroid health effort. Iodine is not an optional trace mineral, no more than vitamin C is optional (else your teeth fall out). The only dangers to iodine replacement are to those who have been starved of iodine for many years; increase iodine and the thyroid can over-respond. I've seen this happen in 2 of the last 300 people who have supplemented iodine.

In my view, neglecting T3 replacement is absurd. While it is not clear to me why many otherwise healthy people have low T3 at the low range of "normal" or even in the below-normal range, people feel better and have better health--faster weight loss, reduced LDL, reduced triglycerides, they are happier and enjoy more energy--when T3 is increased to the upper half of the reference range. (Crucial question: Why is the 5'-deiodinase enzyme that converts T4 to T3 inhibited, resulting in reduced free T3? What is in our diets or environment that is exerting this effect? I don't have answer, but we sorely need one.)

It pays to be a perfectionist when it comes to thyroid. Not only do you feel better, but LDL cholesterol can drop with a statin-like magnitude, but with none of the adverse effects.

If interested, Track Your Plaque offers fingerstick blood spot testing that you can perform in your own home. Each test kit will test for: TSH, free T3, free T4, along with a thyroid peroxidase antibody (a marker for Hashimoto's thyroiditis, an autoimmune inflammatory condition of the thyroid).

Nutrition Syllogism

What do you think of these chains of logic?

Cyanide is a potent lethal poison; carbon monoxide is a less lethal poison.
Therefore: plenty of carbon monoxide is good.




Having uterine cancer is a bad thing. Having uterine fibroids is a less bad thing.
Therefore: plenty of uterine fibroids are good.



These are obvious examples of seriously flawed logic. Students of logic and philosophy will recognize the above erroneous sequences as examples of the twisted arguments often used to persuade an argumentative opponent of the logic of a premise. As long ago as 335 B.C., Greek philosopher, Aristotle, recognized the pitfalls of thinking in such arguments. You think we’d know better by now.

Try this one:

White enriched flour is a bad for health; whole grains are less bad for health.
Therefore: plenty of whole grains are good for health.



Ouch!

In the 1960s, we all ate hot dogs on white buns, white flour Wonder Bread® sandwiches, Mom made cookies and cupcakes with white flour. Then, during the 1970s and 1980s, clinical studies were performed demonstrating that whole wheat and whole grains reduced colon cancer, high blood pressure, diabetes, and heart disease compared to white flour. In other words, add back fiber and B vitamins and health benefits develop: No argument here.

Therefore: whole grains must be good for health. Further, lots of whole grains?unlimited quantities of whole grains many times per day, every day?must be even better. Even the USDA says so on their nutrition pyramid, with 8-11 servings of grains per day, 4 of which should be whole grains, at the widest portion of the pyramid.

But what happens when you follow this logic through and fill your diet with whole grains?

Look around you and it’s easy to see: Appetite increases, people become obese, blood sugar increases, diabetes develops, HDL cholesterol plummets, triglycerides skyrocket, inflammatory patterns (e.g., c-reactive protein, or CRP) increase, small LDL (the number one cause for heart disease in the obese U.S.!) shoots through the roof.

I would no more fill my diet with “healthy whole grains” than I would close my garage door with the car running.

Is pomegranate juice healthy?


Pomegranate juice, 8 oz:

Sugars, total 31.50 g

Sucrose 0.00 g

Glucose (dextrose) 15.64 g

Fructose 15.86 g




In your quest to increase the flavonoids in your diet, do you overexpose yourself to fructose?

Remember: Fructose increases LDL cholesterol, apoprotein B, small LDL, triglycerides, and substantially increases deposition of visceral fat (fructose belly?). How about a slice of whole grain bread with that glass of pomegranate juice? The Heart Association says it's all low-fat!


(Coming on the Track Your Plaque website: A full in-depth Special Report on fructose in all its glorious forms and whether this is truly an issue for your health. Fructose tables and the scientific data to establish a safe "threshold" value will be included.)

Image courtesy Wikipedia

Honeydew melon


Honeydew melon:

Sugars, total 51.97 g

Sucrose 15.87 g

Glucose 17.15 g

Fructose 18.94 g

Because sucrose is half fructose (the other half is glucose), there are approximately 26 grams of fructose per one-half honeydew melon.



Image courtesy Wikipedia
Being regular is dangerous to your health

Being regular is dangerous to your health

No, I'm not referring to your daily morning ritual in the bathroom. I'm talking about heart rate.

Counterintuitively, a perfectly regular heart rate is a marker of poor health. People with perfect regularity of heart rate have more heart attacks, for instance.

Regularity of heart rate occurs more commonly in people with hypertension and other metabolic derangements, and it signals increased risk for both heart attack and death. A perfectly regular heart rate, i.e., no variation in the time interval from beat to beat, suggests that the parasympathetic nervous system, the component of automatic ("autonomic") nervous system control that is associated with the relaxation response, feelings of well-being, quiet, and relaxation, is weak. It also means that the opposing sympathetic nervous sytem that regulates the "fight or flight," adrenaline-like response is allowed to be dominant. Dominance of the sympathetic over the parasympathetic system generates regularity of heart rate. Heart rate also tends to be faster, e.g., 85 beats per minutes rather than 55 or 60 beats per minute. So perfect regularity, as well as increased rate, is undesirable.

What we want is irregularity of heart rate. But not irregularity that occurs chaotically with no rhyme or reason. More precisely, we want variability in heart rate. And we want variability to occur in synchrony with breathing, i.e., the respiratory cycle.

The ideal response is:

1) increase in heart rate with inspiration

2) decrease in heart rate with expiration.

Heart rate in healthy people typically varies 15-20 beats per minute within the respiratory cycle, e.g., 60 bpm at end-exhalation, 80 bpm at end-inspiration.

Restoration of increased heart rate variability is associated with reduced blood pressure, reduced blood sugars (HbA1c), reduced inflammatory markers and cortisol (associated with stress), even an increase in DHEA levels. Feelings of well-being and calm also develop.

Among the strategies to consider to restore heightened heart rate variability and slowed heart rate include:

--Omega-3 fatty acid supplementation
--Exercise
--Weight loss
--Deep breathing exercises
--Meditation, prayer, and biofeedback

For our Track Your Plaque purposes, we are folding in the HeartMath strategies, i.e., use of a heart rate monitor that calculates heart rate variability in the context of respiratory cycle. If you've not already done so, take a look at the two Special Reports devoted to this topic on the Track Your Plaque website.

Comments (21) -

  • Tim Huntley

    9/25/2011 2:06:58 PM |

    Dr. Davis,

    I have spent about 6 months taking daily HRV measurements using a Suunto t6d watch and analyzing the output with a software tool from Kubios.  From my n=1 experience, the most meaningful long-term impact to improved HRV has been regular exercise.  A lot of the research studies I looked at are in agreement with the other factors you mentioned above; however some of the factors tend to be more transitory (breathing, meditation, etc. ) and create a change during the time that you are working on them vs. the more lasting effects from exercise.

    I would be happy to share more specifics from my experience if you are interested.

    ...Tim

  • me@me.com

    9/25/2011 3:20:56 PM |

    Dear "Dr. Davis"

    i'd love to read more !

    warmly
    interested one Smile

  • Geoffrey Levens, L.Ac.

    9/25/2011 4:20:46 PM |

    The folks at Heart Math have had this mastered for years.  Books, classes, seminars, and they sell a portable and a computer based biofeedback device for training "coherence".  I am not affiliated with them in any way and do not sell their products but I do think it is a pretty good way to get into the whole arena of meditation and of very directly training HRV.

  • Diana

    9/25/2011 8:01:23 PM |

    This is really interesting, because it goes along exactly with what I learned in studying midwifery - that hearing an absolutely regular/non-variable heartbeat on a fetoscope is a sign of a seriously compromised baby. Interesting that that carries on into the adult world!

  • LINDA

    9/25/2011 9:19:57 PM |

    (The FASEB Journal. 2011;25:971.10)
    © 2011 FASEB
    ________________________________________
    971.10
    Daily apple consumption promotes cardiovascular health in postmenopausal women
    Sheau C Chai, Shirin Hooshmand, Raz L Saadat and Bahram H Arjmandi
    Nutrition, Food & Exercise Sciences, Florida State University, Tallahassee, FL
    Animal findings suggest that apple and its components, e.g. apple pectin and polyphenols improve lipid metabolism and lower the production of proinflammatory molecules. To our knowledge, the present study is the first that evaluated the cardioprotective effects of daily consumption of apple for one year in postmenopausal women. Qualified women (160) were randomly assigned to one of the two dietary intervention groups: dried apple (75g/day) or comparative control dried fruit. Fasting blood samples were collected at baseline, 3-, 6-, and 12-month to measure various parameters. Our findings indicate that the additional daily caloric intake of ~240 from dried apple not only do not increase body weight but rather lower it by 1.5 kg without altering habitual dietary intake. In this study, apple consumption significantly reduced serum levels of TC and LDL by 14% and 23%, respectively. The daily apple consumption also profoundly improved atherogenic risk ratios in addition to lowering serum levels of lipid hydroperoxide (33%) and C-reactive protein (32%). In conclusion, incorporation of apple into regular diet is encouraged because of its highly favorable effects in reducing the risk factors for cardiovascular disease.
    Grant Funding Source: Partly supported by USDA
    Table of Contents
    This Article
    1.  FASEB J. April 2011 25 (Meeting Abstract Supplement) 971.10
    1.  Â» Meeting Abstract

  • LINDA

    9/25/2011 10:27:18 PM |

    Effects on Thyroid
    The National Institutes of Health (NIH) note that although little scientific data is available about the effects of flax on the thyroid, some experts in natural medicine advise that patients avoid flaxseed in cases of hypothyroidism. (See Resource 2) The Univeristy of Maryland Medical Center also suggests that patients with thyroid disorders stay away from flaxseed and other foods that may interfere with thyroid function. (See Reference 3)
    Goitrogens
    Thiocyanite, a substance found in flax products and other foods, such as apricots, rye, millet and broccoli, might act as a goitrogen-that is, it may block the uptake of iodine in the thyroid gland. When your diet is too rich in goitrogens and too low in iodine, it can cause the thyroid gland to swell and form a lump, or goiter. However, the typical diet in the United States contains enough iodine that problems like goiter have been practically eliminated, so goitrogens should not be a concern for the average American. (See Reference 2, pages 100-101)
    Read more: Flaxseed and Thyroid Disease | eHow.com http://www.ehow.com/facts_5629982_flaxseed-thyroid-disease.html#ixzz1Z0N1SV8j

  • Dr. William Davis

    9/26/2011 12:37:25 PM |

    I didn't know that, Diana!

    That's very interesting, a phenomenon consistent in widely variable situations.

  • Dr. William Davis

    9/26/2011 12:38:51 PM |

    Hi, Geoffrey--

    My experience with HeartMath goes back around 15 years, long ago that I still remember using Holter monitors, shipping the tape to LA, and waiting for the analysis to come back--long delay, no real-time feedback.

    The new do-it-yourself device really changes the entire equation: real-time feedback, much faster results.

  • Dr. William Davis

    9/26/2011 12:41:32 PM |

    Hi, Tim--

    I'd love to hear more! Specifically, what is the heart rate feedback like on your watch? Is it a visible signal?

    You are absolutely correct: Many effects are transitory. However, the more you do it, the more you habituate the response, the more likely it becomes "coherence" occurs spontaneously.

  • Teresa

    9/26/2011 4:14:34 PM |

    HeartMath exercises are more than regular breathing.  They advocate activating a positive feeling, such as gratitude or appreciation, during the breathing exercises.  This helps maintain the increased heart rate variability.  Here is a link to one of their techniques.  

    http://www.heartmath.com/personal-use/quick-coherence-technique.html

    This is a summary of some of the scientific concepts of HeartMath.  It is an older publication, but still interesting to read.

    http://www.heartmath.org/research/science-of-the-heart/introduction.html

    More research studies are listed here.

    http://www.heartmath.org/research/research-library/research-library.html#educational-research

    While the computer programs and gadgets are helpful, they are not essential to learning and being successful with the techniques.

    Teresa

    P.S.  I am not affiliated with HeartMath in any way except that I have a relative who works for them.  I don't make any money off of them.

  • Bill

    9/26/2011 8:03:36 PM |

    With regard to your play on "being regular", apart from being grain free with not one lapse for 4 years, I have been squatting for 5 years and believe it's natural and very beneficial. Strongly recommend!

  • Dr. William Davis

    9/27/2011 2:53:40 AM |

    Hi, Teresa--

    Yes, there are many ways to achieve enhanced parasympathetic tone, HeartMath coherence being one of them.

    You could meditate for months to years, you could perform thermal biofeedback. What I like about HeartMath is its immediate accessibiity.

  • Rita

    9/27/2011 10:44:58 AM |

    This is just a housekeeping issue. I used to get your posts via email but not for months now. When I try to re-subscribe, Feedburner says I am already subscribed, but still no posts come to email. Can you get this fixed? Thanks.

  • Makro

    9/28/2011 12:21:30 PM |

    Dr. Davis - OT question:

    When is WB showing up in the Kindle store? Looking forward to giving it a read.

  • MaryB

    9/28/2011 1:11:31 PM |

    This is very interesting information.  It parallels the test they do for Diabetic Neuropathy.  

    If the heartbeats are the same on inhale and exhale you have it pretty bad.  The closer they are to the same, the worse the Neuropathy is found to be.  They use an EKG test and compare the peaks... If I understand correctly.  This sounds like it relates to what you are discussing Dr. Davis... am I correct

  • MaryB

    9/28/2011 1:14:19 PM |

    hmmm did you read the article?  LOL  This is not about constipation but heartbeats.

  • Lance Strish

    9/28/2011 11:41:33 PM |

    DrGreger talked about heart rate variability in 2009 once
    http://www.youtube.com/watch?v=sK0PHQLpw4U&feature=BFa&list=PL53AA35449C7DD652&lf=PlayList#t=4m
    -
    http://tinyurl.com/drgregerPDF

  • Dr. William Davis

    9/29/2011 1:02:36 AM |

    Yes, indeed, MaryB: Absolutely correct.

    Diabetes, in particular, can lead to a marked lack of heart rate variability and its health consequences.

  • Dr. William Davis

    9/29/2011 1:03:11 AM |

    Hi, Makro--

    It should already be there. Are you outside the U.S.?

  • Dr. William Davis

    9/29/2011 1:04:56 AM |

    Hi, Rita--

    Sorry. Thought this was fixed.

    I'll have it looked into.

  • Ginger

    1/1/2013 4:16:09 AM |

    Any info on stopping PVC's? I don't do caffiene, very little sugar, i do deep breathing and meditation. I'm dairy free and don't eat gluten.

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