Low thyroid: What to do?

8. February 2009 William Davis (25)
I've gotten a number of requests for solutions on how to solve the low thyroid issue if either 1) your doctor refuses to discuss the issue or denies it is present, or 2) there are government mandates against thyroid correction unless certain (outdated) targets are met.

Oh, boy.

While I'm not encouraging anyone to break the laws or regulations of their country (and it's impossible to generalize, with readers of this blog originating from over 30 countries), here are some simple steps to consider that might help you in your quest to correct hypothyroidism:

--Measure your body temperature--First thing in the morning either while lying in bed or go to the bathroom and measure your oral temp. Record it and, if it is consistently lower than 97.0 degrees (Fahrenheit), show it to your doctor. This may help persuade him/her.(You can still be hypothyroid with higher temperatures, but if low temperatures are present, it is simply more persuasive evidence in favor of treatment).

--Supplement with iodine 150 mcg per day to be sure you are not iodine deficient. This is becoming more common in the U.S. as people avoid iodized salt. It is quite common outside the U.S. An easy, inexpensive preparation is kelp tablets.

--Show your doctor a recent crucial study: The HUNT Study that suggests that cardiovascular mortality begins to increase at a TSH of only 1.5 or greater, not the 5.5 mIU usually used by laboratories and doctors.

--Ask people around you whether they are aware of a health practitioner who might be willing to work with you, or at least have an open mind (sadly, an uncommon commodity).

Also, see thyroid advocate and prolific author, Mary Shomon's advice on how to find a doctor willing to work with you. Yes, they are out there, but you may have to ask a lot of friends and acquaintances, or meet and fire a lot of docs. It shouldn't be this way, but it is. It will change through public pressure and education, but not by next week.

Another helpful discussion from Mary Shomon: The TSH Normal Range: Why is there still controversy? You will read that even the endocrinologists (a peculiarly contentious group) seethingly debate what constitutes normal vs. low thyroid function.

Also, you might remind a resistant health practitioner that guidelines are guidelines--they are not laws that restrain anyone. They are simply meant to represent broad population guidelines that do not take your personal health situation into consideration.

Which statin drug is best?

8. February 2009 William Davis (7)
I re-post a Heart Scan Blog post from one year ago, answering the question: Which statin drug is best?

I still get this question from patients in the office and online, nearly always prompted by a TV commercial. So let me re-express my thoughts from a year ago, which have not changed on this issue.


The statin drugs can indeed play a role in a program of coronary plaque control and regression.

However, thanks to the overwhelming marketing (and lobbying and legislative) clout of the drug manufacturing industry, they play an undeserved, oversized role. I get reminded of this whenever I'm pressed to answer the question: "Which statin drug is best?"

In trying to answer this question, we encounter several difficulties:

1) The data nearly all use statins drugs by themselves, as so-called monotherapy. Other than the standard diet--you know, the American Heart Association diet, the one that causes heart disease--it is a statin drug alone that has been studied in the dozens of major trials "validating" statin drug use. The repeated failure of statin drugs to eliminate heart disease and associated events like heart attack keeps being answered by the "lower is better" argument, i.e., if 70% of heart attacks destined to occur still take place, then reduce LDL even further. This is an absurd argument that inevitably encounters a wall of limited effects.

2) The great bulk of clinical data examining both the incidence of cardiovascular events as well as plaque progression or regression have all been sponsored by the drug's manufacturer. It has been well-documnted that, when a drug manufacturer sponsors a trial, the outcome is highly likely to be in favor of that drug. Imagine Ford sponsors a $30 million study to prove that their cars are more reliable and safer. What is the likelihood that the outcome will be in favor of the competition? Very unlikely. Such is human nature.

If we were to accept the clinical trial data at face value and ignore the above issues, then I would come to the conclusion that we should be using Crestor at a dose of 40 mg per day, since that was the regimen used in the ASTEROID Trial that achieved modest reversal of coronary atherosclerotic plaque by intravascular ultrasound.

But I do not advocate such an ASTEROID-like approach for several reasons:

1) In my experience, nobody can tolerate 40 mg of Crestor for more than few weeks, a few months at most. Show me someone who can survive and tolerate Crestor 40 mg per day and I'll show you somebody who survived a 40 foot fall off his roof--sure, it happens, but it's a fluke.

2) The notion that only one drug is necessary to regress this disease is, in my view, absurd. It ignores issues like hypertension, metabolic syndrome, inflammatory phenomena, lipoprotein(a), post-prandial (after-eating) phenomena, LDL particle size, triglycerides, etc. You mean that Crestor 40 mg per day, or other high-intensity statin monotherapy should be enough to overcome all of these patterns and provide maximal potential for coronary plaque reversal? No way.

3) Plaque reversal can occur without a statin agent. While statin drugs may provide some advantage in the reduction of LDL, much of the benefit ends there. All of the other dozens of causes of coronary atherosclerotic plaque need to be addressed.

So which statin is best? This question is evidence of the brainwashing that has seized the public and my colleagues. The question is not which statin is best. The question should be: What steps do I take to maximize my chances of reversing coronary atherosclerotic plaque?

The answer may or may not involve a statin drug, regardless of the subtle differences among them.

Dr. Nancy Sniderman, heart scans on Today Show

5. February 2009 William Davis (6)
While shaving this morning, I caught the report by NBC medical expert, Dr. Nancy Sniderman, about her coronary plaque and CT coronary angiogram.

Visit msnbc.com for Breaking News, World News, and News about the Economy




Those of you in the Track Your Plaque program or who follow The Heart Scan Blog know that we should tell Dr. Sniderman and her doctor that:

She has done virtually nothing that will stop an increasing heart scan score! In fact, Dr. Sniderman is now following the "prevention program" that is eerily reminiscent of Tim Russert's program! We all know how that turned out.

It is pure folly to believe that a combination of Lipitor, exercise, and a "healthy diet" (usually meaning a low-fat diet--yes, the diet that promotes heart disease) will stop the otherwise relentless increase in heart scan score.

Dr. Sniderman, please consider:

1) Having the real causes of your coronary plaque identified. (It is highly unlikely to be just LDL cholesterol, though the drug industry is thrilled that you believe this.)

2) Ask yourself (or, if your doctor knew what she was doing, ask her): Why do I have heart disease? LDL cholesterol is insufficient reason--virtually nobody I know has high LDL cholesterol as the sole cause. LDL cholesterol is, at most, one reason among many others, but is insufficient as a sole cause.

3) What is your vitamin D status? Crucial!

4) What is your thyroid status?

5) Fish oil--a must!

6) Do you have lipoprotein(a)? Small LDL?

Just addressing the items on the above checklist would put you on a far more confident path to stop your heart scan score from increasing.

If you were to repeat your heart scan score, my prediction: Your score will be higher by 18-24% per year.

My personal experience with low thyroid

3. February 2009 William Davis (31)
Something happened to me around October-November of last year.

I usually feel great. Ordinarily, my struggles are sleeping and relaxing. As with most people, I have too many projects on my schedule, though I find my activities stimulating and fascinating.

I blasted through a very demanding November, trying to meet the needs of a book publisher. This involved sleeping only a few hours a night for several days on end, all after a full day of office practice and hospital duties.

But it was getting tougher. My concentration was becoming more fragmented. Getting things done was proving an elusive goal. Exercise became a real chore.

Although I usually force myself to go to sleep, I was starting to fall asleep before my usual bedtime, and I was sleeping longer than usual.

It's been a tough winter in Wisconsin. Let's face it: It's Wisconsin. But it's been tough even for this region, with weeks of temperatures consistently below 10 degrees. Even so, I was having a heck of a time keeping warm. Extra shirts, socks, soaking my hands in hot water--none of it worked and I was freezing.

So I had my thyroid values checked:

Free T3: 2.6 pg/ml (Ref 2.3-4.2)
Free T4: 1.20 ng/dl (Ref 0.89-1.76)
TSH: 1.528 uUI/ml (Ref 0.350-5.500)

Normal by virtually all standards. I measured my first morning oral temperature: 96.1, 96.3, 95.9. Hmmmm.

My experience coincided with the Track Your Plaque and Heart Scan Blog conversations about low thyroid being enormously underappreciated, with the newest data on thyroid disease suggesting that a TSH for ideal health is probably 1.5 mIU or less. (More about that: Is normal TSH too high? and Thyroid perspective update .

Could this simply be a case of medical student-oma in which every beginning medical student believes he has every disease he learns about?

Despite the apparently "normal" thyroid blood tests, I took the leap and started taking Armour thyroid, beginning at 1/2 grain (30 mg), increasing to 1 grain (60 mg) after the first week.

Within 10 days, I experienced:

--Dramatic restoration of the ability to concentrate
--A boost in mood. (In fact, the last few blog posts before I replaced thyroid reflect my deepening crabbiness.)
--Large increase in energy, now restored to old levels
--Need for less sleep
--I'm warm again! (It's still <20 degrees, but I get easily stay warm while indoors.)

I am absolutely, positively convinced of the power of thyroid. I am further convinced from the clinical data, patient experiences, and now my own personal experience, that low levels of hypothyroidism are being dramatically underappreciated and underdiagnosed.

I shudder to think of what my life would have been like 6 months or a year from now without correction of thyroid hormone.

Now, the tough question: Why the heck is this happening to so many people?

Speaking availability

3. February 2009 William Davis (5)
Just a quick announcement:

If you would like to hear more about the concepts articulated in The Heart Scan Blog or in the Track Your Plaque program, I am available to speak to your group.

Among the possible topics:

Return to the Wild: Natural Nutritional Supplements That Supercharge Health
Why this apparent "need" for fish oil and other heart-healthy supplements? I discuss why some nutritional supplements make perfect sense when we are viewed in the context of primitive humans living modern lives, while other supplements do little.


Shrink Your Tummy . . .or, Why Your Dietitian is Fat!
Weight loss doesn't have to involve calorie counting, deprivation, or hunger pangs. But the conventional "rules" for weight loss and health have to be broken.

The Politically Incorrect Guide to Extraordinary Heart Health
Heart health is something that you can seize control over, something identifiable, correctable, and . . . reversible. Much of this can be achieved with little or no medication, nor procedures. I detail all the enormously empowering lessons learned through the Track Your Plaque program.


I can also present in-depth yet entertaining discussions on the power of vitamin D, natural cholesterol control, screening for heart disease, and similar topics covered in the blog.

To learn more, just e-mail us at contact@trackyourplaque, or call my office at 414-456-1123.

Learn how to eat from Survivorman

31. January 2009 William Davis (22)

Look no farther than Discovery Channel to learn how humans were meant to eat.

The Survivorman show documents the (self-filmed) 7-day adventures of Les Stroud, who is dropped into various remote corners of the world to survive on little but ingenuity and will to live. Starting without food or water, the Survivorman scrapes and scrambles in the wilderness for essentials to survive in habitats as far ranging as the Ecuadorian rainforest to sub-arctic Labrador.

What does Survivorman have to do with your nutrition habits?

Everything. The lessons we can learn by watching this TV show are plenty.

Survivorman plays out the life we are supposed to be living: slaughtering wild game with simple handmade tools and his bare hands, identifying plants and berries that are safe to eat, trapping fish, scavenging the kill of other predators. He's even resorted to eating bugs and caterpillars, particularly following several days of unsuccessful hunting and scavenging.

What is notable from the Survivorman experience is what is absent: In the steppe, desert, tundra, or jungle, you will not find bread, fruit drinks, or Cheerios. You won't find farm-fattened, corn-fed livestock with meat marbled with fat.

Imagine the result of such an experience for us, drawn out over 6 months. Even an obese, diabetic, gluttonous, XXX dress size 350-lb woman would return a lean 105 lbs, size 0, non-diabetic, fully able to run miles in the wild tracking game.

Survivorman's quiet desperation of living in the wild, preoccupied with worries over where his next meal might be found, is a stark contrast to the bloated, shelves stacked floor-to-ceiling supermarkets, and our modern society's all-you-can-eat several times per day lifestyle.

Am I advocating selling the car and house and chucking modern society for the "safety" of the jungles of Borneo?

No, of course not. I am advocating taking a lesson from the clever experiment conducted by Mr. Stroud, a return-to-the-wild experience that should teach us something about how perverse our modern nutritional lives have become.

CIS: Carbohydrate intolerance syndrome

28. January 2009 William Davis (28)
Carbohydrate intolerance comes in many shades and colors, shapes and sizes.

I call all of its varieties the Carbohydrate Intolerance Syndrome, or CIS. (Not to be confused with CSI, or Crime Scene Investigation . . . though, come to think of it, perhaps there are some interesting parallels!)

At its extreme, it is called type II diabetes, in which any carbohydrate generates an extravant increase in blood sugar, followed by the domino effect of increased triglycerides, reduction in HDL, creation of small LDL, heightened inflammation, etc. and eventually to kidney disease, coronary atherosclerosis, neuropathies, etc.

An intermediate form of carbohydrate intolerance is called metabolic syndrome, or pre-diabetes. These people, for the most part, look and act like diabetics, though their reaction to carbohydrate intake is not as bad. Blood sugar, for instance, might be 125 mg/dl fasting, 160 mg/dl after eating. The semi-arbitrary definition of metabolic syndrome includes at least three of the following: HDL <40 mg/dl in men, <50 mg/dl in women; triglycerides 150 mg/dl or greater; BP 135/80 or greater; waist circumference >40 inches in men, >35 inches in women; fasting glucose >100 mg/dl.

This is where the conventional definitions stop: Either you are diabetic or have metabolic syndrome, or you have nothing at all.

Unfortunately, this means that the millions of people with patterns not severe enough to match the standard definition of metabolic syndrome are often neglected.

How about Kevin?

Kevin, a 56 year old financial planner, is 5 ft 7 inches, 180 lbs (BMI 28.2). His basic measures:

HDL 36 mg/dl
Triglycerides 333 mg/dl
BP 132/78
Waist circumference 34 inches
Blood sugar 98 mg/dl

Kevin meets the criteria for metabolic syndrome on only two of the five criteria and therefore does not "qualify" for the diagnosis.

Kevin's basic lipids showed LDL 170 mg/dl, HDL 36 mg/dl, triglycerides 333 mg/dl.

But take a look at his underlying lipoprotein patterns (NMR):

LDL particle number 2231 nmol/L (equivalent to a "true" LDL of 223 mg/dl)
Small LDL 1811 nmol/l
Large HDL 0.0 mg/dl


In other words, small LDL constitutes 81% of all LDL particles (1811/2231), a severe pattern. Large HDL is the healthy, protective fraction and Kevin has none. These are high-risk patterns for heart disease. These, too, are patterns of carbohydrate intolerance.

Foods that trigger small LDL and reduction in healthy, large HDL include sugars, wheat, and cornstarch. Kevin is carbohydrate-intolerant, although he lacks the (fasting) blood sugar aspect of carbohydrate intolerance. But he shows all the underlying lipoprotein and other metabolic phenomena associated with carbohydrate intolerance.

We could also cast all three conditions under the umbrella of "insulin resistance." But I prefer Carbohydrate Intolerance Syndrome, or CIS, since it immediately suggests the basic underlying cause: eating carbohydrates, especially those that trigger rapid and substantial surges in blood sugar.

CIS is the Disease of the Century, judging by the figures (both numbers and humans) we are seeing. It will dominate healthcare in its various forms for many years to come.

The first treatment for the Carbohydrate Intolerance Syndrome? Some would say the TZD class of drugs like Avandia. Others would say a DASH or TLC (American Heart Association) diet. How about liposuction, twice-daily Byetta injections, or even the emerging class of drugs to manipulate leptin and adiponectin? How do "heart healthy" foods like Cheerios and Cocoa Puffs fit into this? (Don't believe me? The American Heart Association says they're heart healthy!)

The first treatment for the Carbohydrate Intolerance Syndrome is elimination of carbohydrates, except those that come from raw nuts and seeds, vegetables, occasional real fruit (not those green fake grapes), wine, and dark chocolates.

Making sense out of lipid changes

27. January 2009 William Davis (9)
Maggie had been doing well on her program, enjoying favorable lipids near our 60-60-60 targets (HDL 60 mg/dl or greater, LDL 60 mg/dl or less, triglycerides 60 mg/dl or less). Last fall, her last set of values were:

Total cholesterol: 149 mg/dl
LDL cholesterol: 67 mg/dl
HDL cholesterol: 73 mg/dl
Triglycerides: 43 mg/dl

The holidays, as with most people, involved a frenzy of indulgent eating: Christmas cookies, cakes, pies, stuffing, potatoes, candies, etc.

Maggie returned to the office 6 pounds heavier with these values:

Total cholesterol: 210 mg/dl
LDL cholesterol: 124 mg/dl
HDL cholesterol: 57 mg/dl
Triglycerides: 144 mg/dl

In other words, holiday indulgences caused an increase in LDL cholesterol, a reduction in HDL, an increase in triglycerides, an increase in total cholesterol.

What happened?

At first glance, many of my colleagues would interpret this as fat indulgence and/or a "need" for statin drug therapy.

Having done thousands of lipoprotein panels, I can tell you that, beneath the surface, the following has occurred:

--Overindulgence in carbohydrates from the goodies triggered triglyceride (actually VLDL) formation in the liver, released into the blood.
--Increased triglycerides and VLDL triggered a boom in conversion of large LDL to small LDL (since triglycerides are required to form small LDL particles) via cholesteryl-ester transfer protein (CETP) activity.
--Increased triglycerides and VLDL interacted with HDL particles, causing "remodeling" of HDL particles to the less desirable, less protective small particles, which do not persist as long in the blood, resulting in a reduction of HDL.

The critical factor is carbohydrate intake. This triggered a domino effect that is often misintepreted as excessive fat intake or a genetic predisposition. It is nothing of the kind.

I discussed this phenomenon with Maggie. She now knows to not overindulge in the holiday snacks in future and will revert promptly back to her 60-60-60 values.

How to Give Yourself Hashimoto's Thyroiditis: 101

25. January 2009 William Davis (18)
I borrowed this from the enormously clever Dr. BG at The Animal Pharm Blog.


How to Give Yourself Hashimoto's Thyroiditis: 101

--lack of sunlight/vitamin D/indoor habitation
--mental stress
--more mental stress
--sleep deprivation... (excessive mochas/lattes at Berkeley cafes)
--excessive 'social' calendar
--inherent family history of autoimmune disorders (who doesn't??)
--wheat, wheat, and more wheat ingestion ('comfort foods' craved in times of high cortisol/stress, right? how did I know the carbs were killing me?)
--lack of nutritious food containing EPA DHA, vitamin A, sat fats, minerals, iodine, etc
--lack of play, exercise, movement (or ?overtraining perhaps for Oprah's case)
--weight gain -- which begins an endless self-perpetuating vicous cycle of all the above (Is it stressful to balloon out for no apparent reason? YES)


If you haven't done so already, take a look at Animal Pharm you will get a real kick out of Dr. BG's quick-witted take on things.


We are systematically looking for low thyroid (hypothyroidism) in everyone and findings oodles of it, far more than I ever expected.

Much of the low thyroid phenomena is due to active or previous Hashimoto's thyroiditis, the inflammatory process that exerts destructive effects on the delicate thyroid gland. It is presently unclear how much is due to iodine deficiency in this area, though iodine supplementation by itself (i.e., without thyroid hormone replacement) has not been yielding improved thyroid measures.

I find this bothersome: Is low thyroid function the consequence of direct thyroid toxins (flame retardants like polybrominated diphenyl ethers, pesticide residues in vegetables and fruits, bisphenol A from polycarbonate plastics) or indirect toxins such as wheat via an autoimmune process (similar to that seen in celiac disease)?

I don't know, but we've got to deal with the thyroid-destructive aftermath: Look for thyroid dysfunction, even in those without symptoms, and correct it. This has become a basic tenet of the Track Your Plaque approach for intensive reduction of coronary risk.

Framing

24. January 2009 William Davis (0)
Heart health without a 12" incision



Heart health for less than $44,483 (Cost of a coronary stent according to the American Heart Association 2008 Update)



Track Your Plaque: A drug-free zone



This is your brain on wheat

This is your brain on wheat

10. December 2009 William Davis (32)
Here's just a smattering of the studies performed over the past 30 years on the psychological effects of wheat consumption.

Oddly, this never makes the popular press. But wheat underlies schizophrenia, bipolar illness, behavioral outbursts in autism, Huntington's disease, and attention deficit hyperactivity disorder (ADHD).

The relationship is especially compelling with schizophrenia:

Opioid peptides derived from food proteins: The exorphins.
Zioudrou C et al 1979
"Wheat gluten has been implicated by Dohan and his colleagues in the etiology of schizophrenia and supporting evidence has been provided by others. Our experiments provide a plausible biochemical mechanism for such a role, in the demonstration of the conversion of gluten into peptides with potential central nerovus system actions."


Wheat gluten as a pathogenic factor in schizophrenia
Singh MM et al 1976
"Schizophrenics maintained on a cereal grain-free and milk-free diet and receiving optimal treatment with neuropleptics showed an interruption or reversal of their therapeutic progress during a period of "blind" wheat gluten challenge. The exacerbation of the disease process was not due to variations in neuroleptic doses. After termination of the gluten challenge, the course of improvement was reinstated. The observed effects seemed to be due to a primary schizophrenia-promoting effect of wheat gluten."


Demonstration of high opioid-like activity in isolated peptides from wheat gluten hydrolysates
Huebner FR et al 1984


Is schizophrenia rare if grain is rare?
Dohan FC et al 1984
"Epidemiologic studies demonstrated a strong, dose-dependent relationship between grain intake and the occurrence of schizophrenia."
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Comments (32) -

  • Mike

    12/9/2009 11:27:37 PM |

    Dr. Davis,

       Excellent post!  It's quite apparent the auto-immune stimulating qualities of WGA are behind a plethora of chronic diseases.

    Regarding both cardiovascular disease and obesity, though, is it a similar mechanism, strictly related to inflammation, or a combination of autoimmunity AND inflammation?  I'm often asked why wheat is "worse" than other forms of dense carbohydrates, but I'm at a loss for a simplistic explanation.

  • Charles R.

    12/10/2009 12:24:59 AM |

    You don't have to convince me.

    A number of years ago, I realized wheat was causing me problems, mostly at that time energy problems. If I ate a breakfast with toast, I would get tired almost immediately after. It was probably carbs in general, but I just stopped eating all wheat.

    About 5-6 months after that, I came home, saw a box of saltines on the counter, and devoured them. Within an half-hour, I was going through an incredible depressive episode to the point of having suicidal thoughts. It was like someone had turned on a crazy switch in my brain.

    Totally anecdotal of course, but I tried the same thing a couple of other times and really noticed immediate changes in my ideation and feelings, so got the message and stopped wheat altogether.

  • Michael

    12/10/2009 1:55:00 AM |

    I use wheat grass tablets from Pines.  Is wheat grass harmful like wheat?  I assume the answer is no because there is no gluten in wheat grass.  Am I correct?

  • Kennedy

    12/10/2009 2:31:57 PM |

    Very scary.

  • Anonymous

    12/10/2009 4:11:37 PM |

    How interesting! Thank you for sharing this.

  • Zach

    12/10/2009 4:59:49 PM |

    Dr. Davis,
    I hope you take this as a compliment!  I follow your blog regularly.  Thanks for all of the great info and wisdom that you've shared over the last year with me since I've been an avid reader of your site.

    I also follow Jimmy Moore's site, and saw your picture/name as a participant for an upcoming Low Carb/Fitness Cruise.  I was struck by how your face has really leaned out and is much more muscular/healthy looking.  The picture you currently have on your blog looks good!  I was just wondering whether since your blog picture was taken whether you've leaned out since really bearing down and following a gluten-free diet especially over the last 12+ months?

    Wish I could join you on this cruise, maybe next time.  Thanks again for being at the front of the "normal carb" revolution.

    Best Regards,
    Zach (over at The Paleo Garden)

  • Drs. Cynthia and David

    12/11/2009 12:48:52 AM |

    Here is another report for your list (from Eric Westman at Duke): "Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature" http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652467/?tool=pubmed

    They report the resolution of long standing schizophrenia using a ketogenic diet.

  • Anne

    12/11/2009 4:21:13 AM |

    My brain on wheat(gluten) was fogged and depressed. In fact, I did not know how depressed I was until I stopped eating gluten. I never knew I could feel so good.

    It is well established that gluten can cause seizures and other neurological problems. You can read articles and abstracts about the neurological effects of gluten in The Gluten File http://jccglutenfree.googlepages.com/theneurologicalmanifestationsofgluten

    What does this have to do with my heart? Well, my pitting edema and shortness of breath disappeared when I stopped eating wheat.

  • Michael

    12/11/2009 4:35:39 AM |

    I take wheat grass tablets by Pines.  Is wheat grass harmful like wheat?

  • Adam

    12/11/2009 6:44:24 AM |

    I've been on a no wheat diet for over a month now. Unfortunately, I can't say I've felt anything in the way of mental benefits. Or any benefits at all really.

    But then, I'm pretty healthy overall. I exercise at least an hour a day, and I'm relatively young.

    I must conclude that abstaining from wheat is either most beneficial to the unhealthy/elderly, or is a bunch of a hooey Smile

  • Tim

    12/11/2009 12:06:50 PM |

    Do you have more information on wheat and Huntington's Disease? Has anyone been able to prevent this disease by eliminating wheat from the diet? What evidence is there?

    Thanks

  • Dr. William Davis

    12/11/2009 12:52:47 PM |

    Wheat grass and breads like Ezekiel, to my knowledge, have no gluten. This makes them less harmful, though the bread still poses carbohydrate challenge issues.

  • Dr. William Davis

    12/11/2009 12:53:58 PM |

    Tim--

    Dr. Loren Cordain of The Paleo Diet has talked about the relationship of wheat and Huntington's recently in his latest newsletter. He sums up the literature very nicely.

  • Nigel Kinbrum BSc(Hons)Eng

    12/11/2009 6:42:49 PM |

    According to Cereal Grains:
    Humanity’s Double-Edged Sword,     gluten can cause C(o)eliac Disease, Dermatitis Herpetiformis, Sjogren's Syndrome and Cerebellar Ataxia.

    My ex-G/F used to get intensely itchy spots on her skin and she also had dry eyes. When she went gluten-free on my suggestion, the itchy spots disappeared and her eyes got a little less dry, but she still has to use artificial tears. She also commented that her belly was less bloated since going gluten-free. Result!

    A lady I know has a son with Xeroderma Pigmentosum and Cerebellar Ataxia. When she put her son on a gluten-free diet after reading the above article that I'd e-mailed her a link to, he improved dramatically and began doing things that his mum thought he would never be able to do, as he was previously deteriorating. Result!

  • Aileen

    12/11/2009 11:15:55 PM |

    I think this is a bit extremist. Whilst those effects do exist in some people, along with problems with other food groups such as Solanaceae they are not ubiquitous by any means.  There are lots of people out there who can eat anything including wheat, dairy and other food groups with gay abandon and suffer NO adverse effects. Opioid peptides are also acknowledged as occurring in other foods such as eggs and OATS and when you think about it the potential is there for them to come out of ANY protein since all proteins are broken down into peptides for digestion.

    So, whilst people do need to be aware that they can have intolerances to a wide range of foods for various reasons I think making blanket statements such as this that may compel people to exclude large numbers of food products from their diet for perhaps no good reason, is dangerous and irresponsible.

    Anyone suspecting problems with food groups should see an allergist and go through the process of a proper food elimination diet.

    I do also appreciate that food intolerances can come and go for a range of reasons.

  • Anne

    12/11/2009 11:31:23 PM |

    Food for Life makes Ezekiel bread and it is not the list of gluten free products. http://www.foodforlife.com/our-products.html

    Other breads that people often ask about are Sami's and Delands. Although they contain no gluten grains, when tested they showed high amounts of gluten.

    So if you have celiac disease or gluten sensitivity, you need to avoid these products.

    Wheat grass would be gluten free as long as there are no seeds.

  • Dr. William Davis

    12/12/2009 12:04:02 AM |

    Hi, Zach--

    Started thyroid replacement when my T3 went real low. I think that did it.

    Thanks for noticing.

  • Dr. William Davis

    12/12/2009 12:06:12 AM |

    Sorry, Aileen. All proteins do not break down into the same polypeptides, since there are numerous and varying sequences of amino acids that differ, say, between oats, wheat, beef, nuts, etc.

    So a polypeptide is not always the same polypeptide. Referring to a basic biochemistry text would show this quite clearly.

    If you think you've escaped the ill-effects of this ubiquitous, more often than not you're wrong. You just haven't realized it yet.

  • JPB

    12/12/2009 2:09:30 AM |

    Now you should write a post on the effects of wheat plus statins....

  • Aileen

    12/12/2009 6:37:26 AM |

    I do know my biochemistry thanks!  I didn't say all proteins break down into the same peptides. Also having been through a proper elimination diet in te past I can say with certainty that gluten/wheat/dairy give me no ill effects.

    As with all things in life everyone is different, different populations of receptors in the brain hence different sensitivities and responses.  You can't blanket say gluten (or anything else) is bad for you.

    And as with many other things in life - often you don't find stuff out till you look for it.  How many studies on red wine are quoted and its only now they are beginning to look at white wine and find many of the same effects!

  • Anonymous

    12/13/2009 9:05:50 PM |

    Aileen, YOU GO GIRL!  Dr D., you were a bit quick on the put down.

    I like that Dr Davis is passionate about CAD risk reduction but I frequently post here when I see generalizations based on limited or cherry picked studies. That is the sort of thing, oh I don't know, big pharma would do.

    We don't all have to live like Inuit, there are plenty of vegetarians that are healthy and have no ill effects from eating wheat gluten every day. Or does someone have a study to say all vegetarians are lethargic and overweight?

    Trevor

  • Anonymous

    12/15/2009 12:40:28 AM |

    Hi there,

    Just wondering if you are a member of THINCS (http://www.thincs.org/) run by Dr.Uffe Ravnskov,

  • Anonymous

    1/30/2010 4:27:51 PM |

    Aileen,

    Yes of course not all will get mental illnesses from gluten and a big proportion will not get immediate reaction to gluten. However, it has been shown that it can cause schizophrenia in a small part of the population. Around 30% of normal healthy people produce antibodies to gluten that can be measured in the stool. There are even reports of disappearance of schizophrenia, all sorts of unexplained fatigue and other mental illnesses. There is a strong correlation between gluten consumption and schizophrenia as well.

    Now, cannabis has been shows to cause schizophrenia and other mental problems too. Not all will get it and a lot of people can live reasonable lives with it. Would you say cannabis is bad and causes mental illnesses, when similar to gluten it causes various mental problems in a significant proportion of the population? The difference between them is that cannabis has immediate psychoactive properties in almost everyone, so people have no problem believing it's problematic. Gluten does contain exorphins, which do have opioid-like activities. Also the immunogenic factor causing gut malfunction and nutrient malabsorption. How you will handle the opioids and what effects the antibodies and immune system activation will have on your body, no one knows.

    Even if you don't get immediate reactions from wheat, I wouldn't bet my life on its harmfulness.

  • lib

    4/17/2010 10:03:30 AM |

    3 months ago i began to eliminate processed food and alchohol from my diet.It has been hard but i have lost 7 kilos and have been feeling great.
    Yesterday i was excessively bad ,gave in (the story of my life) and had 3 weetbix,foccacia bread,2 jam donuts.2 beers and 2 pieces of white flat bread.
    Well today i feel dreadful.This afternoon i yelled,slammed doors,verbally abused my husband went into depression and had suicidal thoughts.
    I have suffered from depression in the past but never as severe as this!
    I strongly believe it was due to the wheat consumption,so I went on to the web and typed in 'wheat and depression" and found your site.After reading a few of the blogs i thought i muat be right.Incredible.
    Well i will be avoiding wheat now as i have another reason too not just for weight loss.
    I'll introduce wheat say in another 2 months time and see if i get the same reaction.It may not be pleasant but will convince me.

  • Anonymous

    7/12/2010 7:39:24 PM |

    Hi, just found your site.  A year ago after going thru horrible female issues and tons of unexplained medical problems I met a nurse who told me to cut out wheat.  I was in the process of having biopsies because no Dr. could figure out what was wrong with me.  

    I have no cancerSmile I won't list all the things wrong with me at the time but it was bad, and I was doubting my sanity.  I've always struggled with depression. Cutting out the wheat has helped so much. Most of my health problems went away.  

    I may eat a little bit here and there, but not often. I find myself in tears soon after and the depression and body aches come back.

    It is a shame that so many Dr.'s know nothing of this or tell me it's all hype. Thank God for the internet, at least now we know we aren't crazy and the wheat problem is finally getting some attention.

  • buy jeans

    11/3/2010 9:10:14 PM |

    Oddly, this never makes the popular press. But wheat underlies schizophrenia, bipolar illness, behavioral outbursts in autism, Huntington's disease, and attention deficit hyperactivity disorder (ADHD).

  • Anonymous

    2/8/2011 6:51:25 PM |

    Aileen,

    If people limited all gluten grains to just 2 or 3% of their diet it would probably be fine.  BUT, the huge problem is that people think their cereal is healthy.  Then they think their whole wheat bread is healthy.  Then they think their pasta is healthy.  By now we are approaching 50 to 75% of their diet.  Then people serve breaded chicken nuggets to their kids.  It is literally killing people.

    Dr. Davis is a hero!  Many Drs. do not even take the time to care.

  • majkinetor

    3/9/2011 9:49:18 AM |

    Anonimous said: "Now, cannabis has been shows to cause schizophrenia and other mental problems too. Not all will get it and a lot of people can live reasonable lives with it".

    Cannabis DOES NOT cause schizophrenia, that is outdated and probably politicized research. The marijuana smoking is a symptom rather then cause of schizophrenia. Brain CB1 receptors are endogenously used by Anandamide neurotransmitter which is very low in schizophrenic people. THC is more potent version of Anandamide and thats the reason schizophrenic people use it more then regular people who already have normal levels of endogenous version. Cannabis is used as a medicine for most of the history.

  • JT

    7/11/2011 12:11:31 PM |

    Seriously?
    Crackers make you want to kill yourself?
    Your problems stretch far beyond wheat, sir.

  • stuart

    8/24/2011 3:55:54 PM |

    JT,

    Just because you don't understand the entirety of the problem, try not to belittle Charles.  Charles may have been exaggerating a bit.  Yes, the problems extend far beyond wheat because wheat infects almost all junk food, processed food, fast food, and "premium" prepared foods.  

    Maybe it is time you wise up JT.  Just go to a restaurant with a Gluten free menu.  Then compare all the offerings on that menu to the regular menu.  You guessed it JT,  EVERYTHING else has gluten.  Even the minestrone soup, coffee creamer, ice cream, etc.  Why?  Wheat is the quickest and cheapest way to "thicken" and to make products seem "rich".  

    Wheat is just another method of control.  Keeping the rich wealthy and the poor dumb and sick.

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