Throw away total cholesterol!

Richard's total cholesterol without treatment was 186 mg/dl. "That's great!" his doctor declared, referring to the conventional dictum that total cholesterols less than 200 carry low risk. Several fingersticks in a mall kiosk set up by a local hospital to check total cholesterols confirmed Richard's low number.

But after Richard's unexpected hospitalization and two stents for severe coronary blockages, he demanded better answers.

Tragically, the answer was there all along: Despite a "favorable" total cholesterol, his HDL ("good") cholesterol was a miserable 32 mg (ideal >60 mg).

Total cholesterol is actually the sum total of HDL cholesterol, LDL cholesterol, with a contribution from triglycerides. That's why a low total cholesterol can conceal a low HDL.

This situation is quite common. And low HDL is accompanied by a constellation of other undesirable causes of heart disease, most notably small LDL.

Don't accept total cholesterol as your sole measure of risk. It's nearly worthless. If you live in Bangladesh or a third world country, well perhaps that's the best you can get. But if you live in the U.S. or developed world, it's absurd to rely on total cholesterol.

Smart Start not so smart




Kellogg's has crafted a campaign to support the American Heart Association featuring acress Sela Ward. Her attractive face, familiar to many TV and movie viewers, does add a comforting face to their efforts.

What's in this cereal made by the manufacturers of Pop-Tarts, Cheez-It, Rice Krispies, and Chips Deluxe cookies?

There are, indeed, some healthy ingredients: oat bran, potassium; you can even get a version made with soy protein. But there's sugar listed as the second ingredient. High-fructose corn syrup is also listed prominently. (Remember this issue? High-fructose corn syrup causes overwhelming sugar cravings, causes your triglycerides to skyrocket, and is probably among the principal food ingredients that make you obese.)

Upon detailed questioning of my patients struggling to lose weight, this and products like it are often among the "healthy" foods they've gravitated towards. We spend a great deal of time dissuading them of this idea.

A one-cup serving of Smart Start is low in fat (1 gram) but contains 43 grams of carbohydates, of which there are 14 grams of sugar. There are a meager 3 grams of fiber. To me, this sounds like a cupcake.

The Kellogg's people are exceptionally clever marketers. Partner with the American Heart Association and movie stars? Brilliant!

You should trust food manufacturer advertising about as much as you trust drug manufacturer advertising, which is to say not at all.

Kellogg's sold $10 billion dollars of food products last year. They are the world's leading producer of breakfast cereals. They are a leading producer of convenience foods: cookies, crackers, cereal bars, and frozen waffles under the brands Keebler, Pop-Tarts, Eggo, Cheez-It, Nutri-Grain, Rice Krispies, Famous Amos, and Kashi.

Can they cash in on healthy trends? They'll certainly try.

Does anybody have a normal vitamin D level?

We now routinely check everyone's vitamin D blood level at the start of the program. (The measure to obtain is 25-OH-Vitamin D3. This is not to be confused with 1,25-OH2-vitamin D3, which is a kidney function measure.)

Of the 10 people with levels drawn today, none were even close to normal levels (which we define as 50 ng/ml)--not a single one.

The majority were in the range of severe deficiency (<20 ng/ml). Only two had levels in the 30s. None had higher. (Remember: I'm talking about people in Wisconsin, a terribly sunlight-deprived area much of the year. This might not apply quite as vigorously to Florida residents or others in sun-exposed regions.)

Curiously, I've also seen several people this week who had extraordinary quantities of coronary plaque on their heart scans (scores >1000), all of whom had extremely low vitamin D levels. One of these people had fairly unimpressive lipoproteins, with very minimal abnormalities identified. (This is quite unusual, by the way.) It makes you wonder if a profound deficiency of vitamin D is sufficient to act on its own as an instigator of coronary plaque.

The more we examine the issue of vitamin D deficiency, the more fascinating it gets. I suspect we've just scratched the surface and there's a lot more to learn about this tremendously interesting nutrient. Nonetheless, with what we're seeing in our experience, I'm urging everyone to get a blood vitamin D level.

Don't believe your LDL cholesterol!

Harry's case is typical. For years, his doctor told him his LDL cholesterol of 123 mg was okay. But a heart scan score of 490 (90th percentile at age 52) made him question just where his coronary plaque came from.

Lipoprotein analysis told a very different story: His LDL particle number was 2400 nmol, meaning his trueLDL was more like 240 mg, nearly double the value of LDL obtained through his doctor. Harry had other sources of risk, too, but the LDL particle number was a clear stand-out.

Why does this happen? How can LDL cholesterol be so terribly inaccurate?

LDL cholesterols obtained in virtually all labs are not measured, they're calculated. The calculation was developed in the 1960s by Dr. Friedewald at the National Institutes of Health and therefore goes by his name (the Friedewald calculation). Dr. Friedewald derived this simple calculation to permit doctors across the U.S. to obtain LDL cholesterols, which were technically difficult to measure in those days by using measured HDL, total cholesterol and triglycerides.

Doctors were told that the only time that the Friedewald calculated LDL was inaccurate was when triglycerides exceeded 400 mg. So most family practitioners and internists still believe that calculated LDL's are, for the most part, quite accurate.

Nothing could be further from the truth. When LDL's are actually meaured, you find that LDL is rarely accurate. In fact, in our experience, inaccuracy of 30-50% is the rule, sometimes 100%. The one telltale hint that calculated LDL is wrong is when HDL is <50 mg--that's nearly everybody.

So what's your LDL? You won't really know unless it's measured. Our preferred method is NMR (LipoScience) LDL particle number, probably the most accurate of all. Second best: apoprotein B, direct measured LDL, and non-HDL. (We'll cover this issue much more extensively in an upcoming report on the www.cureality.com website in an extensive Special Report.)

Are you the exception?


I read about 40 heart scans this morning. In the stack was a 41-year old man with a heart scan score of 841.

That's terribly high for anyone, let alone a 41-year old person. He's lucky to find out about this before catastrophe strikes.

People like this worry me. In general, we advise men to consider a heart scan age 40 and older; women 50 and older. If there's anything exceptional about your family history or your own history, then you might notch these numbers down another 5-10 years. For instance, if your Dad had a heart attack at age 43, you might consider a scan at age 35. Or, if you've had diabetes for several years and you're a 42-year old woman, you might think about a scan. (Men tend to develop measurable plaque by heart scans 10 years before women.)

There are no hard and fast rules. It's unusual for a male to have a score >0 before age 40. Likewise, it's very uncommon for a woman to have a score >0 before age 50. But there are occasional exceptions--but they can be very important exceptions.

Our 41-year old man with the score of 841, for instance, probably had a high score since his mid-30s. I've seen several women without any obvious risk factors with scores in the several hundred range in their early 40s.

My rule: When in doubt, opt for safety. Every day, I still read about people in their 30s, 40s, and 50s dying of heart attacks. It shouldn't happen.

When in doubt, get the heart scan. The most you'll lose is the cost of the scan and a modest exposure to radiation. If your score is zero, you know you're safe for the next 5 or more years. But if you have an exceptional score at a young age, take preventive action.

Self-empowerment in health: The new wave in health care

Track Your Plaque is just one facet of the broad and powerful emerging wave of self-empowerment in health.

Hospitals, drug and device manufacturers, and the medical establishment don't like this idea. People managing their own health? That's ridiculous! Dangerous! But mostly unprofitable.

Self-empowerment means having easy access to simple, safe, and inexpensive diagnostic tests like heart scans, carotid scans, bone densitometry (for osteoporosis), cholesterol tests, abdominal ultrasound, even brain scans (e.g., CT or MRI) for people with a family history of brain aneurysm.

Opponents of this idea worry about the "false-positives" that come about with broad testing, i.e, detection of abnormalities that are artifactual. Our experience is that false-positives are only an occasional problem with any test. Instead, we find that most people have many true-positives. In CT heart scanning, for example, we find many unsuspected enlarged aortas (potential future aneurysms), valve disorders, and aortic calcium. These are all important in a preventive program. Unfortunately, your doctor's definition of false-positive often means that no corrective procedure or operation is required.

Other evidence that self-empowerment in health is growing:

--The nutritional supplement movement. What better example of power in managing your own health is there than the fabulous array of nutritional supplements available?

--Medications moving to over-the-counter status. Gradually, more and more medications are trickling into availability for you to obtain without a doctor's prescription.

--What I call "retail imaging", i.e. screening ultrasound, heart scans, full body scans, etc. that are available in most states without a doctor's order.

--The Internet. The rapidity and depth of information available on the Internet today is mind-boggling. It will fuel the self-empowerment movement by providing sophisticated information to the health care consumer previously available only through your physician.

--High-deductible health insurance plans. If health care consumers will bear more and more of the costs of health care, they will seize greater responsibility for early identification and prevention to minimize long-term costs.

There are more. But the movement is powerful and broad--and unstoppable. Let the establishment with vested interests in preserving the status quo fuss and complain, just like horse and buggy manufacturers did in the early 1900's when the autmobile came along.

Vitamin D deficiency is rampant

Today alone I've seen several people with severe deficiencies of vitamin D.

We're now checking everyone's blood vitamin D level at the start of the program. The measure that most accurately reflects your vitamin D status is 25-OH-vitamin D3. This is very confusing to many physicians, who traditionally have thought of 1,25-di-Hydroxy vitamin D3 as the standard test to measure. What they're failing to recognize is that this second measure is a kidney product, not a reflection of vitamin D status.

Using 25-OH-vitamin D3, several people today alone had levels of <10 ng/ml, clearly in the category of severe deficiency (generally regarded as <20ng/ml).

The majority of people we see in the office are Wisconsin residents. It's no wonder they're deficient. Although it's mid-May, we've seen the sun only a handful of days this year. And most of the days have been too chilly to wear short sleeves and shorts to permit sufficient surface area for UV exposure.

Living in a sunny climate, however, is no guarantee that you have sufficient blood vitamin D levels. Two recent studies have shown that 30-50% of the residents of sunny southern Florida and Hawaii are also deficient. (Why, I'm not sure.)

Although our experience thus far is anecdotal in several hundred people, my impression is that people who have normal blood levels of vitamin D (we regard normal as 45-50 ng/ml) have a far easier time of halting or regressing coronary plaque.

Vitamin D is among the most exciting nutritional tools we've come across in a long time. The conversation is making the media, which impresses me tremendously, given the fact that nobody stands to profit financially to any significant degree through vitamin D supplementation.

For a wonderful collection of discussions on vitamin D, go to Dr. John Cannell's website, www.vitaminDcouncil.com. You'll find a huge quantity of scientific background and conversation on the whole idea. I believe you will be thoroughly impressed with just how powerful the argument in favor of vitamin D has become.

What if wheat products were illegal?

Imagine if anything made of wheat were illegal: bread, bagels, crackers, pasta, pretzels, donuts, Shredded Wheat cereal, Raisin Bran, pastry, cookies, cakes, cupcakes. . . Your grocery store would then be unable to carry any of these products.

How empty would the grocery store shelves be?

There would be very little. The stores would be filled instead with vegetables and fruits, meats, and dairy products. But aisle after aisle would be empty. There'd be no cereal aisle. There'd be no snack chip aisle. The ordinarily overcrowded bread shelves wouldn't be there.

Bakery? Nope, not there either. Pasta and noodles? Empty. How about cakes and pastries? Also gone.

Getting the picture? American groceries are dominated by wheat products. What would happen to your health and the health of your family if wheat were abruptly removed from your choices? Would you be less healthy?

No. In fact, your health would be hugely improved. You'd lose a significant quantity of weight. Extraordinary numbers of people would lose diabetic or pre-diabetic tendencies. Feelings of sluggishness, sleepiness, and moodiness would dissolve. Blood pressure would be reduced. The incidence of cancer, skin disease, and inflammatory diseases would plumet.

From a plaque control perspective, your HDL cholesterol would rise, triglycerides drop. Small LDL would improve dramatically.

The message: Slash wheat products from your diet. Yes, you'll miss the smell and taste of freshly baked bread. But you'll do it for many more healthy years. And you may do it without a 14 inch scar in your chest.

The sobering tale of small LDL

Every day, I learn to respect small LDL more and more.

Small LDL particles, and its evil partner, low HDL, is among the most common reasons why someone fails to fully gain control of coronary plaque and heart disease risk.

Just yesterday, I saw a slender businessman (6 feet 1 inch in height, 186 lb.) whose small pattern persisted despite niacin, fish oil, oat bran, and raw almonds. We generally think of small LDL as an overweight person's pattern, but in some people the genetics are quite powerful and it can be expressed even in slender people.

The solution: More physical activity and exercise; cut back on processed carbohydrates, particularly wheat products like breads, pasta, crackers, breakfast cereals; think about magnesium (see our two recent reports on magnesium on the www.cureality.com membership website, the latest report to be posted this week); be sure sleep is adequate (gauge this by whether you're energetic during the day and don't fall asleep watching TV or movies). Lack of sufficient physical activity in people with sedentary jobs is probably among the most common reason the small LDL pattern persists.

Ignore small LDL and it can be like a hidden cancer in your body, growing and metastasizing (not literally, of course), fueling coronary plaque growth. Be sure your doctor assesses whether you have small LDL if you hope to gain control of your coronary risk.

Burn off the fat

If you've ever wondered just how many calories you're burning with various activities like yard work, driving, climbing stairs, etc. go to this great website that will calculate it for you: http://www.caloriecontrol.org/exercalc.html.

Here are some examples:


Dancing for 30 minutes(fast, e.g., tango): 193 calories
Yoga for 30 minutes: 204 calories
Washing the car for 30 minutes: 173 calories
Vacuuming for 30 minutes: 88 calories

(All are for a 170 lb person.)

As you see, physical activity does not necessarily have to consist of exercise. It doesn't require fancy equipment or expensive outfits. But it does require you to keep moving. Sedentary work is among the most common reasons I see in my patients for failing to control weight and its associated lipoprotein patterns, like low HDL and small LDL.

If your work is sedentary, then a minimum of 60 minutes of physical activity per day is necessary to begin to correct weight-related patterns. If you gauge by calories burned, then a useful goal is 500 calories per day in physical activity--at a minimum.
This is your brain on wheat

This is your brain on wheat

Here's just a smattering of the studies performed over the past 30 years on the psychological effects of wheat consumption.

Oddly, this never makes the popular press. But wheat underlies schizophrenia, bipolar illness, behavioral outbursts in autism, Huntington's disease, and attention deficit hyperactivity disorder (ADHD).

The relationship is especially compelling with schizophrenia:

Opioid peptides derived from food proteins: The exorphins.
Zioudrou C et al 1979
"Wheat gluten has been implicated by Dohan and his colleagues in the etiology of schizophrenia and supporting evidence has been provided by others. Our experiments provide a plausible biochemical mechanism for such a role, in the demonstration of the conversion of gluten into peptides with potential central nerovus system actions."


Wheat gluten as a pathogenic factor in schizophrenia
Singh MM et al 1976
"Schizophrenics maintained on a cereal grain-free and milk-free diet and receiving optimal treatment with neuropleptics showed an interruption or reversal of their therapeutic progress during a period of "blind" wheat gluten challenge. The exacerbation of the disease process was not due to variations in neuroleptic doses. After termination of the gluten challenge, the course of improvement was reinstated. The observed effects seemed to be due to a primary schizophrenia-promoting effect of wheat gluten."


Demonstration of high opioid-like activity in isolated peptides from wheat gluten hydrolysates
Huebner FR et al 1984


Is schizophrenia rare if grain is rare?
Dohan FC et al 1984
"Epidemiologic studies demonstrated a strong, dose-dependent relationship between grain intake and the occurrence of schizophrenia."

Comments (32) -

  • Mike

    12/9/2009 11:27:37 PM |

    Dr. Davis,

       Excellent post!  It's quite apparent the auto-immune stimulating qualities of WGA are behind a plethora of chronic diseases.

    Regarding both cardiovascular disease and obesity, though, is it a similar mechanism, strictly related to inflammation, or a combination of autoimmunity AND inflammation?  I'm often asked why wheat is "worse" than other forms of dense carbohydrates, but I'm at a loss for a simplistic explanation.

  • Charles R.

    12/10/2009 12:24:59 AM |

    You don't have to convince me.

    A number of years ago, I realized wheat was causing me problems, mostly at that time energy problems. If I ate a breakfast with toast, I would get tired almost immediately after. It was probably carbs in general, but I just stopped eating all wheat.

    About 5-6 months after that, I came home, saw a box of saltines on the counter, and devoured them. Within an half-hour, I was going through an incredible depressive episode to the point of having suicidal thoughts. It was like someone had turned on a crazy switch in my brain.

    Totally anecdotal of course, but I tried the same thing a couple of other times and really noticed immediate changes in my ideation and feelings, so got the message and stopped wheat altogether.

  • Michael

    12/10/2009 1:55:00 AM |

    I use wheat grass tablets from Pines.  Is wheat grass harmful like wheat?  I assume the answer is no because there is no gluten in wheat grass.  Am I correct?

  • Kennedy

    12/10/2009 2:31:57 PM |

    Very scary.

  • Anonymous

    12/10/2009 4:11:37 PM |

    How interesting! Thank you for sharing this.

  • Zach

    12/10/2009 4:59:49 PM |

    Dr. Davis,
    I hope you take this as a compliment!  I follow your blog regularly.  Thanks for all of the great info and wisdom that you've shared over the last year with me since I've been an avid reader of your site.

    I also follow Jimmy Moore's site, and saw your picture/name as a participant for an upcoming Low Carb/Fitness Cruise.  I was struck by how your face has really leaned out and is much more muscular/healthy looking.  The picture you currently have on your blog looks good!  I was just wondering whether since your blog picture was taken whether you've leaned out since really bearing down and following a gluten-free diet especially over the last 12+ months?

    Wish I could join you on this cruise, maybe next time.  Thanks again for being at the front of the "normal carb" revolution.

    Best Regards,
    Zach (over at The Paleo Garden)

  • Drs. Cynthia and David

    12/11/2009 12:48:52 AM |

    Here is another report for your list (from Eric Westman at Duke): "Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature" http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652467/?tool=pubmed

    They report the resolution of long standing schizophrenia using a ketogenic diet.

  • Anne

    12/11/2009 4:21:13 AM |

    My brain on wheat(gluten) was fogged and depressed. In fact, I did not know how depressed I was until I stopped eating gluten. I never knew I could feel so good.

    It is well established that gluten can cause seizures and other neurological problems. You can read articles and abstracts about the neurological effects of gluten in The Gluten File http://jccglutenfree.googlepages.com/theneurologicalmanifestationsofgluten

    What does this have to do with my heart? Well, my pitting edema and shortness of breath disappeared when I stopped eating wheat.

  • Michael

    12/11/2009 4:35:39 AM |

    I take wheat grass tablets by Pines.  Is wheat grass harmful like wheat?

  • Adam

    12/11/2009 6:44:24 AM |

    I've been on a no wheat diet for over a month now. Unfortunately, I can't say I've felt anything in the way of mental benefits. Or any benefits at all really.

    But then, I'm pretty healthy overall. I exercise at least an hour a day, and I'm relatively young.

    I must conclude that abstaining from wheat is either most beneficial to the unhealthy/elderly, or is a bunch of a hooey Smile

  • Tim

    12/11/2009 12:06:50 PM |

    Do you have more information on wheat and Huntington's Disease? Has anyone been able to prevent this disease by eliminating wheat from the diet? What evidence is there?

    Thanks

  • Dr. William Davis

    12/11/2009 12:52:47 PM |

    Wheat grass and breads like Ezekiel, to my knowledge, have no gluten. This makes them less harmful, though the bread still poses carbohydrate challenge issues.

  • Dr. William Davis

    12/11/2009 12:53:58 PM |

    Tim--

    Dr. Loren Cordain of The Paleo Diet has talked about the relationship of wheat and Huntington's recently in his latest newsletter. He sums up the literature very nicely.

  • Nigel Kinbrum BSc(Hons)Eng

    12/11/2009 6:42:49 PM |

    According to Cereal Grains:
    Humanity’s Double-Edged Sword,
    gluten can cause C(o)eliac Disease, Dermatitis Herpetiformis, Sjogren's Syndrome and Cerebellar Ataxia.

    My ex-G/F used to get intensely itchy spots on her skin and she also had dry eyes. When she went gluten-free on my suggestion, the itchy spots disappeared and her eyes got a little less dry, but she still has to use artificial tears. She also commented that her belly was less bloated since going gluten-free. Result!

    A lady I know has a son with Xeroderma Pigmentosum and Cerebellar Ataxia. When she put her son on a gluten-free diet after reading the above article that I'd e-mailed her a link to, he improved dramatically and began doing things that his mum thought he would never be able to do, as he was previously deteriorating. Result!

  • Aileen

    12/11/2009 11:15:55 PM |

    I think this is a bit extremist. Whilst those effects do exist in some people, along with problems with other food groups such as Solanaceae they are not ubiquitous by any means.  There are lots of people out there who can eat anything including wheat, dairy and other food groups with gay abandon and suffer NO adverse effects. Opioid peptides are also acknowledged as occurring in other foods such as eggs and OATS and when you think about it the potential is there for them to come out of ANY protein since all proteins are broken down into peptides for digestion.

    So, whilst people do need to be aware that they can have intolerances to a wide range of foods for various reasons I think making blanket statements such as this that may compel people to exclude large numbers of food products from their diet for perhaps no good reason, is dangerous and irresponsible.

    Anyone suspecting problems with food groups should see an allergist and go through the process of a proper food elimination diet.

    I do also appreciate that food intolerances can come and go for a range of reasons.

  • Anne

    12/11/2009 11:31:23 PM |

    Food for Life makes Ezekiel bread and it is not the list of gluten free products. http://www.foodforlife.com/our-products.html

    Other breads that people often ask about are Sami's and Delands. Although they contain no gluten grains, when tested they showed high amounts of gluten.

    So if you have celiac disease or gluten sensitivity, you need to avoid these products.

    Wheat grass would be gluten free as long as there are no seeds.

  • Dr. William Davis

    12/12/2009 12:04:02 AM |

    Hi, Zach--

    Started thyroid replacement when my T3 went real low. I think that did it.

    Thanks for noticing.

  • Dr. William Davis

    12/12/2009 12:06:12 AM |

    Sorry, Aileen. All proteins do not break down into the same polypeptides, since there are numerous and varying sequences of amino acids that differ, say, between oats, wheat, beef, nuts, etc.

    So a polypeptide is not always the same polypeptide. Referring to a basic biochemistry text would show this quite clearly.

    If you think you've escaped the ill-effects of this ubiquitous, more often than not you're wrong. You just haven't realized it yet.

  • JPB

    12/12/2009 2:09:30 AM |

    Now you should write a post on the effects of wheat plus statins....

  • Aileen

    12/12/2009 6:37:26 AM |

    I do know my biochemistry thanks!  I didn't say all proteins break down into the same peptides. Also having been through a proper elimination diet in te past I can say with certainty that gluten/wheat/dairy give me no ill effects.

    As with all things in life everyone is different, different populations of receptors in the brain hence different sensitivities and responses.  You can't blanket say gluten (or anything else) is bad for you.

    And as with many other things in life - often you don't find stuff out till you look for it.  How many studies on red wine are quoted and its only now they are beginning to look at white wine and find many of the same effects!

  • Anonymous

    12/13/2009 9:05:50 PM |

    Aileen, YOU GO GIRL!  Dr D., you were a bit quick on the put down.

    I like that Dr Davis is passionate about CAD risk reduction but I frequently post here when I see generalizations based on limited or cherry picked studies. That is the sort of thing, oh I don't know, big pharma would do.

    We don't all have to live like Inuit, there are plenty of vegetarians that are healthy and have no ill effects from eating wheat gluten every day. Or does someone have a study to say all vegetarians are lethargic and overweight?

    Trevor

  • Anonymous

    12/15/2009 12:40:28 AM |

    Hi there,

    Just wondering if you are a member of THINCS (http://www.thincs.org/) run by Dr.Uffe Ravnskov,

  • Anonymous

    1/30/2010 4:27:51 PM |

    Aileen,

    Yes of course not all will get mental illnesses from gluten and a big proportion will not get immediate reaction to gluten. However, it has been shown that it can cause schizophrenia in a small part of the population. Around 30% of normal healthy people produce antibodies to gluten that can be measured in the stool. There are even reports of disappearance of schizophrenia, all sorts of unexplained fatigue and other mental illnesses. There is a strong correlation between gluten consumption and schizophrenia as well.

    Now, cannabis has been shows to cause schizophrenia and other mental problems too. Not all will get it and a lot of people can live reasonable lives with it. Would you say cannabis is bad and causes mental illnesses, when similar to gluten it causes various mental problems in a significant proportion of the population? The difference between them is that cannabis has immediate psychoactive properties in almost everyone, so people have no problem believing it's problematic. Gluten does contain exorphins, which do have opioid-like activities. Also the immunogenic factor causing gut malfunction and nutrient malabsorption. How you will handle the opioids and what effects the antibodies and immune system activation will have on your body, no one knows.

    Even if you don't get immediate reactions from wheat, I wouldn't bet my life on its harmfulness.

  • lib

    4/17/2010 10:03:30 AM |

    3 months ago i began to eliminate processed food and alchohol from my diet.It has been hard but i have lost 7 kilos and have been feeling great.
    Yesterday i was excessively bad ,gave in (the story of my life) and had 3 weetbix,foccacia bread,2 jam donuts.2 beers and 2 pieces of white flat bread.
    Well today i feel dreadful.This afternoon i yelled,slammed doors,verbally abused my husband went into depression and had suicidal thoughts.
    I have suffered from depression in the past but never as severe as this!
    I strongly believe it was due to the wheat consumption,so I went on to the web and typed in 'wheat and depression" and found your site.After reading a few of the blogs i thought i muat be right.Incredible.
    Well i will be avoiding wheat now as i have another reason too not just for weight loss.
    I'll introduce wheat say in another 2 months time and see if i get the same reaction.It may not be pleasant but will convince me.

  • Anonymous

    7/12/2010 7:39:24 PM |

    Hi, just found your site.  A year ago after going thru horrible female issues and tons of unexplained medical problems I met a nurse who told me to cut out wheat.  I was in the process of having biopsies because no Dr. could figure out what was wrong with me.  

    I have no cancerSmile I won't list all the things wrong with me at the time but it was bad, and I was doubting my sanity.  I've always struggled with depression. Cutting out the wheat has helped so much. Most of my health problems went away.  

    I may eat a little bit here and there, but not often. I find myself in tears soon after and the depression and body aches come back.

    It is a shame that so many Dr.'s know nothing of this or tell me it's all hype. Thank God for the internet, at least now we know we aren't crazy and the wheat problem is finally getting some attention.

  • buy jeans

    11/3/2010 9:10:14 PM |

    Oddly, this never makes the popular press. But wheat underlies schizophrenia, bipolar illness, behavioral outbursts in autism, Huntington's disease, and attention deficit hyperactivity disorder (ADHD).

  • Anonymous

    2/8/2011 6:51:25 PM |

    Aileen,

    If people limited all gluten grains to just 2 or 3% of their diet it would probably be fine.  BUT, the huge problem is that people think their cereal is healthy.  Then they think their whole wheat bread is healthy.  Then they think their pasta is healthy.  By now we are approaching 50 to 75% of their diet.  Then people serve breaded chicken nuggets to their kids.  It is literally killing people.

    Dr. Davis is a hero!  Many Drs. do not even take the time to care.

  • majkinetor

    3/9/2011 9:49:18 AM |

    Anonimous said: "Now, cannabis has been shows to cause schizophrenia and other mental problems too. Not all will get it and a lot of people can live reasonable lives with it".

    Cannabis DOES NOT cause schizophrenia, that is outdated and probably politicized research. The marijuana smoking is a symptom rather then cause of schizophrenia. Brain CB1 receptors are endogenously used by Anandamide neurotransmitter which is very low in schizophrenic people. THC is more potent version of Anandamide and thats the reason schizophrenic people use it more then regular people who already have normal levels of endogenous version. Cannabis is used as a medicine for most of the history.

  • JT

    7/11/2011 12:11:31 PM |

    Seriously?
    Crackers make you want to kill yourself?
    Your problems stretch far beyond wheat, sir.

  • stuart

    8/24/2011 3:55:54 PM |

    JT,

    Just because you don't understand the entirety of the problem, try not to belittle Charles.  Charles may have been exaggerating a bit.  Yes, the problems extend far beyond wheat because wheat infects almost all junk food, processed food, fast food, and "premium" prepared foods.  

    Maybe it is time you wise up JT.  Just go to a restaurant with a Gluten free menu.  Then compare all the offerings on that menu to the regular menu.  You guessed it JT,  EVERYTHING else has gluten.  Even the minestrone soup, coffee creamer, ice cream, etc.  Why?  Wheat is the quickest and cheapest way to "thicken" and to make products seem "rich".  

    Wheat is just another method of control.  Keeping the rich wealthy and the poor dumb and sick.

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