Stents, defibrillators, and other profit-making opportunities

As a practicing cardiologst, every day I receive a dozen or more magazines or newspapers targeting practicing physicians, not to mention the hundreds of letters, postcards, invitations to "talks", etc. that I receive. All of these materials share one common goal: To get the practicing cardiologist/physician to insert more of a manufacturer's stents, defibrillators, prescribe more of their drugs, etc.

This is a highly effective and profitable area. Pfizer's Lipitor, for instance, generated $12.2 billion just last year alone. This kind of money will fund an extraordinary amount of marketing.

I'm on the www.heart.org mailing list, a website for cardiologists. I'd estimate that 90% or more of their content is device-related: discussions of situations in which to insert stents, the expanding world of implantable devices, the ups and downs of various drugs. Rarely are discussions of healthy lifestyles, exercise, nutritional supplements, part of the dialogue.

How can you protect yourself from the brainwashed physician, flooded with visions of all the devices he can put in you, all the drugs that can "cure" your disease? Simple: information. Be better informed. Ask pointed questions. The idiotic lay press tells you to ask a doctor about his education. That's not generally the problem. Some of the best educated doc's I know are also the most flagrantly guilty of profiteering medicine.

Ask your doctor about his/her philosphy about the use of medications, devices, etc. If their word is God, take it or leave it, run the other way.

Will radiation kill you?

Several people have asked me lately if radiation is truly dangerous. These conversations were sparked by an editorial comment made on a column I wrote for Life Extension Magazine's April, 2006 issue on "Three ways to detect hidden heart disease".

Among the methods that were discussed in this piece was, of course, CT heart scanning. Anyone who is involved with CT heart scans Quickly recognizes the spectacular power of this test to uncover hidden, unsuspected heart disease, literally within seconds. In 2006, there's really nothing like it for the every day person to have hidden heart disease detected and precisely quantified.

Yet, the "rebuttal" to my article claimed that the broad use of heart scans was only my personal view and that, in truth, radiation kills people.

NONSENSE! If an ovarian cancer is discovered by a CT scan of the abdomen, is that unwise use of radiation? If pneumonia or lung cancer is discovered on a chest x-ray with minimal radiation exposure, have we performed a disservice. Of course not. In fact, these are often lifesaving applications of radiation.

Can radiation be used unwisely with excessive exposure? Of course. The 64 slice CT angiograms are just an example of this. Dr. Mehmet Oz announced on Oprah recently that this was a test to be used for broad screening of women for heart disease. This is wrong. The radiation required for a full 64 slice CT angiogram test is truly excessive for a screening application. You wouln't want to get breast cancer from your mammogram, would you? The radiation from a 64-slice CT angiogram is similar to that of a heart catheterization in the hospital--too much for screening. This is not to be confused with a CT heart scan for a calcium score performed on a 64 slice device. I think this can be performed with acceptable radiation exposure.

Think about what would happen, for instance, if you had your heart disease undetected, had a heart attack, and went to the hospital? During your hospitalization, you'd likely get five chest x-rays, a heart catheterization, perhaps one or more nuclear imaging tests, maybe even a full CT scan (with far more radiation than a screening heart scan). The amount of radiation of a heart scan is trivial compared to what you obtain in a hospital.

So take it all in perspective. The low level of radiation required for a simple heart scan (not an angiogram) does not by itself substantially add to your lifetime risk of radiation exposure. It may, in fact, save your life or reduce your life long exposure to radiation.

Are you using bogus supplements?

I consider nutritional supplements an important, many times a critical,part of a coronary plaque control program.

But use the wrong brand or use it in the wrong way, and you can obtain no benefit. Occasionally, you can even suffer adverse effects.

Take coenzyme Q10, for instance. (Track Your Plaque Members: A full, in-depth Special Report on coenzyme Q10 will be on the website in the next couple of weeks.) Take the wrong brand to minimize the likelihood of statin-related muscle aches, and you may find taking Lipitor, Zocor, Crestor, etc. intolerable or impossible. However, take a 100 mg preparation from a trusted manufacturer in an oil-based capsule, and you are far more likely to avoid the inevitable muscle aches. (Though, of course, consult with your doctor, for all it's worth, if you develop muscle aches on any of these prescription agents.)

Unfortunately, you and I often don't truly know for a fact if a bottle from the shelf of a health food store or drugstore is accurately labeled, pure, free of contaminants, and efficacious.

One really great service for people serious about supplements is the www.consumerlab.com website. They are a membership website (with dues very reasonable) started by a physician interested in ensuring supplement quality. Consumer Lab tests nutritional supplements to determine whether it 1) contains what the label claims, and 2) is free of contamination. (I have no reason to pitch this or any other site; it's just a great service.) They recently found a supplement with Dr. Andrew Weil's name on it to have excess quantities of lead!

What Consumer Lab does not do is determine efficacy. In other words, they do a responsible job of reporting on what clinical studies have been performed to support the use of a specific supplement. However, true claims of efficacy of supplement X to treat symptom or disease Y can only come with FDA approval. Supplements rarely will be put through the financial rigors of this process.

If you're not a serious supplement user, but just need a reliable source, we've had good experiences with:

--GNC--the national chain
--Vitamin Shoppe--also a national chain
--www.lifeextension.com or www.lef.org--A great and low-priced source, but they do charge a $75 annual membership that comes with a subscription to their magazine, Life Extension (which I frequently write for) and several free supplements that you may or may not need. Again, I'm not pitching them; they are simply a good source.
--Solgar--a major manufacturer
--Vitamin World
--Nature's Bounty
--Sundown

There are many others, as well. Unfortunately, it's only the occasional manufacturer or distributor that permits unnacceptable contamination with lead or other poisons, or inaccurately labels their supplement (e.g., contains 1000 mg of glucosamine when it really contains 200 mg). I have not come across any manufacturer/distributor who has systemtically marketed uniformly bad products.

It really helps to have someone to lean on

Among my patients are several husband and wife teams, both of whom have heart disease by some measure. Several couples, for instance, consist of a huband who's received a stent, survived a heart attack, or has some other scar of the conventional approach. The wives generally have a substantial heart scan score in the several hundred range.

There are a few couples for which the roles are reversed: wife with bypass, heart attack, etc. and husband with a substantial quantity of coronary plaque by CT heart scan.

From them all, however, I've learned the power of teamwork. When both wife and husband (or even "significant other") are committed to the effort of controlling or reversing heart disease risk, the likelihood of success is magnified many-fold. Everything is easier: shopping for and choosing foods, incorporating supplements in the budget, taking vacations with a healthy focus, following through and sticking with your program.

Several of the couples have succeeded in obtaining regression of plaque for both man and woman. Both have reduced their heart scan scores and, as a result, dramatically reduced the potential for future heart attack and procedures.

Unfortunately, I will also see the opposite situation: One spouse committed to the program but the other indifferent. They may say such things as "You can't control what happens in the future." Or, "There's no way you can get rid of risk for heart disease. My doctor says it's hereditary." Or, "I've eaten this way since I was a kid. I'm not changing now for you or for anybody else."

Such negative commentary can't help but erode your commitment to health. Most of us recognize these sorts of comments as self-fulfulling and self-defeating.

What should you do if you have an unsupportive partner? Not easy. But it really can help to seek out a supportive partner, whether it's a friend, relative, or other significant person in your life. Of course, not everybody can find such a person. Perhaps that's another way our program can help.

I'd like to hear from anyone who does obtain substantial support of someone close, or if you are struggling to do so.

Five foods that can booby trap your heart disease prevention program

There are several foods that commonly come up on people's lists of habitual foods that are truly undesirable for a heart disease prevention program. Curiously, people choose these foods because of the mis-perception that they are healthy. My patients are often shocked when I tell them that they are not healthy and are, in fact, detrimental to their program.

I'm not talking about foods that are obviously unhealthy. You know these: fried foods, greasy cheeseburgers, French fries, bacon, sausage, etc. Nearly everyone knows that the high saturated fat content, low fiber, and low nutritional value of these foods are behind heart disease, hypertension, and a variety of cancers.

I'm talking about foods that people say they eat because they view them as healthy--but they're not.

Here's the list:

1) Low-fat or non-fat salad dressings--Virtually all brands we've examined have high-fructose corn syrup as one the main ingredients. What does high fructose corn syrup do? Triggers sugar cravings, makes your triglycerides skyrocket (causing formation of abnormal lipoproteins like small LDL), and causes diabetes. The average American now ingests nearly 80 lbs of this evil sweetener per year. You're far better off with olive, canol, grapeseed, or flaxseed based salad dressings.

2) Breakfast cereals--If you've been following these discussions, you know that the majority of breakfast cereals are sugar. They may not actually contain sugar, but they contain ingredients that are converted to sugar in your body. They may be cleverly disguised as healthy--Raisin Bran, Shredded Wheat, etc.

3) Pretzels--"A low-fat snack". That's right. A low-fat snack that raises blood sugar like eating table sugar from the bowl.

4) Margarine--Forget this silly argument about which is worse, butter or margarine. Which is worse, strychnine or lead? Both are poisons to the human body. Who cares which is worse? Fortunately, there are now healthy "margarines" like Smart Balance and Benecol that lack the saturated fat or hydrogenated fat of either.

4) Bananas--Bananas are not all that intrinsically unhealthy. The problem is that people will say to me, "Oh sure, I eat fruit. Two bananas a day." What I hear is "I don't really eat fruit with high nutrient value, fiber, and reduced sugar release. I reach for only bananas which yield extreme sugar rises in my blood and are low fiber." Aren't they high in potassium? Yes, but there are better sources. Cut back if you are a banana freak.


Why the mis-perceptions? A holdover from the low-fat diet days and marketing from food manufacturers are the principal reasons. Of course, foods are meant to be enjoyed, but be informed about it. Choose foods for the right reasons, not because of some cleverly-crafted marketing campaign.

Breakfast of champions?

I spend time every day educating or reminding patients that breakfast cereals are not health foods.

I see jaws drop in shock when I tell them that, in my opinion and despite the marketing claims, Cheerios, Raisin Bran, Shredded Wheat, and the like do not yield health benefits. In fact, they do the the opposite: dramatically raise blood sugar and trigger an adverse cascade of events that eventually leads to diabetes and heart disease.

Why the health claims in advertising? Because these products contain insoluble fiber, the sort that makes your bowels regular. Yes, your bowels are important to health, too. But the benefits end there.

Breakfast cereals are a highly refined, processed food that are not good for your plaque control program. What they are is a highly profitable, multi-billion dollar business, deeply entrenched in American culture ("They'rrrre grrrrrreat!"--Tony the Tiger; "There's a whole scoop of raisins in every box of Post Raisin Bran!" Bet you remember them all.)

I find it particularly upsetting when I see the stamp of approval from the American Heart Association on some products. Gee, if the Heart Association says it's good for you, it must be true! Don't you believe it. The American Heart Association relies on corporate donations, just like any other charity.

If you must eat breakfast cereals, refer to www.glycemicindex.com for a full database of glycemic indexes. You can look up a specific product and it will list its glycemic index, or sugar-releasing properties. You should try to keep glycemic index of the foods you choose below 50.

For a revealing discussion of the influence of food marketers on our perceptions of food, see Track Your Plaque nutrition expert, Gay Riley's discussion The Marketing of Food and Diets in America at her website, www.netnutritionist.com.

In heart disease prevention, shoot for perfection

It really struck me today that it's the people who've chosen to compromise their prevention program who end up with trouble--heart procedures, heart attack, even heart failure.

Take Bob, for example. Bob is 73 years old and had a bypass operation in 2000. The procedure went well and Bob enjoyed 6 years of seemingly trouble-free life. Bob had a seriously low HDL cholesterol for which he as taken a modest dose of niacin, but was unwilling to do much more. His HDL cholesterol was thererefore "stalled" at around 40 mg. (We aim for 60 mg or greater.) We talked repeatedly about the options for increasing HDL but Bob was content with his results. After all, since his bypass operation, he'd felt well and could do all he wanted without physical limitation.

But Bob underwent a stress test for surveillance purposes (which we routinely do 5 or more years after bypass surgery). The test was markedly abnormal with two major areas of poor blood flow to his heart (signalling potential heart attack in future). Bob ended up getting 5 stents to salvage two bypass grafts, both of which showed signs of substantial degeneration.

I've seen this scenario repeatedly: A person is unwilling to go the extra mile to obtain perfection in lipid/lipoprotein patterns, lifestyle changes, and taking the basic, required supplements. Compromises eventually catch up to you in the form of another heart attack, more procedures, heart failure, physical disability, even death.

The message: Don't draw compromises in heart disease prevention. Coronary plaque is a chronic process. It will take advantage of you if you ever let your guard down.

The epidemic of small LDL

Of the patients I saw in my office yesterday, virtually EVERYONE had small LDL.

Small LDL is emerging as an extraordinarily prevalent lipoprotein pattern that drives coronary plaque growth. Previous estimates have put small LDL as affecting only 20-30% of people with coronary disease. However, in my experience in the last few years, I would estimate that greater than 80% of people with measurable coronary plaque have small LDL.

If you have a heart scan score >zero, chances are you have it, too.

I call small LDL a "modern" disease because it has skyrocketed in prevalence recently because of the great surge in inactivity in Americans.

When's the last time you walked to the grocery store and back, lugging two bags of groceries? How many years has it been since you've push-mowed your lawn? All the small conveniences of life have permeated further and further into our activities. Most of us spend the great majority of our day right where you are now--on your duff.

On the bright side, small LDL in most people is reducable by simply getting up and going. But the old teaching of 30 minutes of activity per day is now outdated. This was true when the other hours of your life included physical activities, like housework or a moderately active job. However, if the other 23 1/2 hours of your day are sedentary, then 30 minutes a day won't do it. An hour or more of activity, whether exercise or physical labor of some variety will get you better small LDL-suppressing results.

For most people with small LDL, fish oil and niacin are also necessary to fully suppress small LDL to the Track Your Plaque goal of <10 mg/dl.

A great discussion on vitamin D

If you need better convincing that vitamin D is among the most underappreciated but crucial vitamins for health, see Russell Martin's review of vitamin D and its role in cancer prevention. You'll find it in March, 2006 Life Extension Magazine or their www.LEF.org website at:

http://search.lef.org/cgi-src-bin/MsmGo.exe?grab_id=0&page_id=1308&query=vitamin%20d&hiword=VITAM%20VITAMER%20VITAMERS%20VITAMI%20VITAMINA%20VITAMINAS%20VITAMINC%20VITAMIND%20VITAMINE%20VITAMINEN%20VITAMINES%20VITAMINIC%20VITAMINK%20VITAMINS%20d%20vitamin%20

Our preliminary experience over the past year suggests that vitamin D may be the crucial missing link in many people's plaque control program. We've had a handful of people who, despite an otherwise perfect program (LDL<60, HDL>60, etc.; vigorous exercise, healthy food selection, etc.--I mean perfect)continued to show plaque growth. The rate of growth was slower than the natural expected rate of 30% per year, but still frightening rates of 14-18% per year--until we added vitamin D. All of a sudden, we saw dramatic regression of 7-25% in 6 months to a year.

This does not mean that vitamin D all by itself regresses plaque. I believe it means that vitamin D exerts a "permissive" effect, allowing all the other treatments (fish oil, LDL reduction, HDL raising, correction of small LDL, etc.) to exert their full benefit. So please don't stop everything and just take D. This will not work. However, adding vitamin D to your program on top of the basic Track Your Plaque approach--that's the best way I know of.

MSNBC Report: We need more heart procedures!

A recent headline from MSNBC by Robert Bazell reads:

NEW YORK - Angioplasty, bypass surgery and cholesterol-lowering medications are among the many interventions that have brought a sharp decrease in heart disease deaths in recent years. But, as Dr. Sharon Hayes of the Mayo Clinic points out, there is one big problem.

“The death rates in women have not declined as much as they have in men,” she says.

The piece goes on to suggest that women are getting short-ended in the diagnosis of heart symptoms and heart attack. The solution: More testing to assess the need for procedures like bypass.

This is typical of the device and medication-dominated media consciousness: More procedures, more medication, more devices. Who's paying for advertising, after all? The money at stake is huge. But is this what you want?

Don't be swayed by media reporters with limited understanding of the real issues (at best), consciousness of who's paying for advertising (at worst). Yes, heart disese is often underestimated or misdiagnosed in women. The answer is better detection earlier in life followed by efforts to halt the process--effective, safe treatments for people's benefit, not just profit.
Lovaza vs fish oil supplements?

Lovaza vs fish oil supplements?

Lovaza is the FDA-approved form of fish oil that is available only by prescription. It contains 842 mg of the omega-3 fatty acids, EPA and DHA, per capsule.

The FDA application for Lovaza is viewable here on the FDA website. Interestingly, while there is plenty of the usual regulatory gobbledy-gook about toxicology, dose escalation, and efficacy in the extensive documentation, there is little said about the issue of contamination.

In other words, critics of nutritional supplement fish oil harp on the possibility of contamination with mercury and pesticide residues, like dioxin and PCBs (polychlorinated biphenyls). Yet there is virtually nothing about these same issues in the FDA application for Lovaza.

Let's take a look at a sample over-the-counter fish oil product. Our friends at PharmaNutrients (a new Track Your Plaque partner for nutritional supplements) have a fish oil product called PharmaNutrients" Cardio. Here's an independent analysis of the Cardio product (per 1000 mg fish oil capsule):

EPA content: 566.1 mg
DHA content: 216.6 mg
(Total EPA + DHA 782.7 mg)

Cardio passed all tests for peroxides, PCBs, dioxin, furans, dioxin-like PCBs, and heavy metals (arsenic, cadmium, lead, mercury) using criteria at least 60% more stringent than European Commission (EC) standards (EC standard <2 picograms/gm for dioxins and furans, PharmaNutrients <1 picograms/gm; EC standard <10 picograms/gm for dioxin-like PCBs, PharmaNutrients <3 picograms/gm). PCBs levels in particular are less than 0.009 ppm, 90% below the industry-wide purity standard of 0.09 ppm. Likewise, mercury is >90% lower than European Commission standards.

In other words, this over-the-counter "pharmaceutical grade" fish oil has virtually nothing but omega-3 fatty acids.

Interestingly, the PharmaNutrients fish oil capsule also contains the third omega-3 fatty acid, docosapentaenoic acid (DPA), a neglected form that some authorities have proposed has superior cardiovascular protective properties over eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). If DPA is included in the analysis, PharmaNutrient's Cardio contains a total of 900 mg omega-3 fatty acids per capsule.

At some point, I'd like to see a head-to-head comparison not just on purity grounds, since I am convinced that high-quality products like Cardio can match or exceed the purity of prescription fish oil, but on efficacy in raising omega-3 blood levels, the omega-3 index. (The omega-3 index is a predictor of heart attack and sudden cardiac death--the higher, the better.) My prediction: High-quality fish oil supplements will match or exceed prescription fish oil.

Comments (55) -

  • Renfrew

    1/27/2010 4:23:08 PM |

    Yes, quality and contamination of fish oil IS important.
    I have heard that KRILL oil is superior to fish oil on all fronts. It supposedly has much less contamination than fish oil, better bioavailability (bound to phospholipids) and additional ingredients, i.e. Zeaxanthin (important for retinal health).
    Can you comment on this?

    Thanks.

  • Anonymous

    1/27/2010 5:35:45 PM |

    "My prediction: High-quality fish oil supplements will match or exceed prescription fish oil."

    Not to mention the incredible difference in price... in the patients' favor... and not the pharmaceutical company's bottom line!

    madcook

  • Anonymous

    1/27/2010 6:24:52 PM |

    After my sample bottle of Lovaza from my physician was done, I switched over to Trader Joe's brand. It's really cheap at $10 per bottle and the EPA/DHA concentration is 50%. I take about 5 to 6 capsules a day and my last triglyceride in December was 109 (down from 255). I also tried Omapure too but it's pretty expensive. Omapure's advantage over the TJ stuff is that it is independently tested by IFOS. Who knows where TJ's stuff comes from? I tried the Spring Valley (or is it Nature Made) brand from Walmart. Pure nastiness! Stay away from those yellow bottles.

    I bet some MBA guy dreamed up Lovaza at a brainstorming session intended to come up with ideas to boost sales in a sagging economy.

    Dr. Davis, your EPA/DHA content listings in the post seem to contradict the label on the bottle. The bottle claims 2 capsules contain 1100 mg of EPA and 500 mg of DHA. That would translate to 550 mg of EPA and 250 mg of DHA. What am I missing?

    -- Boris

  • William Trumbower

    1/27/2010 6:26:05 PM |

    I always suggest opening fish oil capsules once in a while to see if the oil is stinky.  That is the advantage of liquid oils is that you can smell and taste them.  One of my nurses opened a Lovaza capsule and told me it made her gag it was so fishy.  The antioxidant used in Lovaza is hydrogenated soybean oil!!.  One of my patients who is sensitive to soy reacted to Lovaza with a rash.

  • Anonymous

    1/27/2010 7:12:37 PM |

    Dr. Davis,

    The following question was somewhat inspired by this post, although it relates more specifically to seafood consumption.

    A few months back, I started ordering seafood from Vital Choice. According to the Vital Choice website, their Albacore tuna has 0.05 ppm of methyl mercury and that number falls to 0.03 ppm for their sockeye salmon (which Is what I typically order).

    http://www.vitalchoice.com/uploads/Merc%20Comp%204_06.pdf

    I often hear a general guideline that 2 servings of non-predatory fish (preferably wild caught and definitely not farm-raised) is generally accepted as safe, or at least minimally risky, and that this is likely a good guideline for everyone, but especially pregnant women and children.

    However, when I would place a sizable order, I would find myself serving it at least 2, and often up to 4 times per week. So that would be up to 4 servings of roughly 4-6 ounces of fish during some weeks that I would serve to my wife and for myself.

    In your opinion, should we cut back to 2 or fewer servings or are the levels listed by Vital Choice low enough to skirt potential issues?

    NOTE: the only seafood I eat is what I purchase from Vital Choice, so that I know the source. While the methylmercury is a focus, I am also curious if this level of consumption is also risky in terms of PCB’s and dioxins. It’s frustrating to realize that there will always be some measure of inherent risk.

    My wife and I aren’t eating this in place of supplementing with a purified fish oil supplement, we simply add this to it, so on days when we eat fish we lower our dose a bit and on days we don’t, we bump up that dosage. Our primary reason for consuming it is the delicious taste, along with the “bonuses” of protein, astaxanthin, vitamin D, and omega 3’s that come along for the ride.

    On one final note, I am also curious if the selenium content of the seafood is at all protective against methylmercury, particularly at these lower levels found in the Vital Choice fish. I’ve heard selenium has the potential to chelate methylmercury, but I am uncertain if this lessens the risk to any noteworthy degree, that is if I am not misinformed to begin with on this front.

    -Rick Bachmann

  • Ateronon

    1/27/2010 8:27:15 PM |

    I'd need a second job to buy either one. Kirkland from Costco is my favorite.

  • Jenny

    1/27/2010 8:50:40 PM |

    One concern with all over the counter supplements, is that they are not continually tested. The test is applied to one batch of the supplement, perhaps years earlier.

    As a result, when random samples are sent to labs contamination is often found in supplements that claim to be free of contaminants.

    I don't know if there is better supervision in the case of products sold as pharamceuticals, but I think we have to be very careful in accepting purity claims from any company operating in the Wild West unregulated supplement market. The track record when these products are spot checked is terrible.

  • Peter

    1/27/2010 10:34:53 PM |

    Another question that (I think) is yet to be answered is if DHA enriched fish oil is more effective than normal DHA/EPA fish oil at improving a person's omega-3 index.

  • Ned Kock

    1/28/2010 3:35:28 AM |

    Another option is to eat sardines whole - approx. 1.6 g of omega-3 per 100 g - about 2 sardines, according to my estimation:

    http://healthcorrelator.blogspot.com/search/label/recipe

    These are wild-caught sardines, not the canned ones.

  • Anonymous

    1/28/2010 9:59:15 PM |

    Your promotion of PharmaNutrients' Cardio is quite shocking. The price for 15 capsules is $29.95. That's $2/capsule - not far from $4/capsule of Lovaza. Surely you must remember your own post "Lovaza rip-off"?
    http://heartscanblog.blogspot.com/2008/12/lovaza-rip-off.html

  • Dr. William Davis

    1/29/2010 2:50:13 AM |

    Ren-

    While I think that krill oil is a fascinating product that we have used, I feel that the manufacturer's over-the-top marketing has clouded its real value. It is absurd to propose that krill oil be used as a replacement for fish oil until we have 1) confident data on omega-3 RBC levels, and 2) outcome data.

    In other words, fish oil has been shown to dramatically reduce cardiovascular risk. Krill doesn't yet enjoy this advantage. While it might be true, it is premature to make claims to that effect.

  • Dr. William Davis

    1/29/2010 2:51:28 AM |

    HI, Rick--

    Sorry, but I've not heard about this argument that selenium counteracts the mercury in fish. That seems a bit of a stretch.

    Any idea where this came from?

  • Dr. William Davis

    1/29/2010 2:54:57 AM |

    Hi, Jenny-

    Sorry, but I've got to disagree with you on this one.

    Take a look, for instance, at the two analyses by Consumer Lab (www.consumerlab.com). 77 fish oil products tested; 2 flunked due to oxidative byproducts. None flunked due to mercury, dioxin, PCBs, or related compounds. This has held true in Consumer Report and several other analyses.

    Frankly, I wouldn't be caught dead taking Lovaza, because I care too much about healthcare costs. Why stick it to other people when I can buy fish oil for a lot less?

  • Anonymous

    1/29/2010 7:18:36 PM |

    Jenny, I've seen you bashing supplements before.  Do you have any references for your claims?

  • Adolfo David

    1/30/2010 2:45:26 AM |

    Biotivia is going to launch a 100% vegetarian Omega 3 about which says has teh greatest EPA DHA levels around, also with resveratrol, green tea or sesame lignans. I would prefer Omega 3 in one supplement and resveratrol in others, not together because children pregnants..shouldnt possible take resveratrol. But I am so intriguing with a vegetarian Omega 3 with high levels of EPA DHA, arent you?

  • Anonymous

    1/30/2010 6:25:28 AM |

    I strongly agree that Lovaza is a rip-off.

    But unfortunately, the brand it's being compared to (PharmaNutrients) is a rip-off too. Once upon a time you were mentioning the benefits of Costco brand fish oil, or cheaper alternatives. $30/bottle isn't really cheap, when anyone can go to iHerb and get much better deals.

    Jarrow Formulas, EPA-DHA Balance, 630mg/Gel -- $13 for 120 softgels. Or 240 softgels for $23.

    PharmaNutrients vitamin D is another ripoff. $20 for 120 gels, 2000IU. I can get 120 gels of 5000IU for around $8 at iHerb (Now brand).

    I question why you decided to choose PharmaNutrients as a partner, when they are clearly so overpriced.

  • William Trumbower

    1/30/2010 6:46:00 PM |

    Do any of you have any experience with Vectomega, a phospholipid coated salmon oil?

  • Dr. William Davis

    1/31/2010 3:18:51 PM |

    Hi, Dr. Trumbower--

    Only limited experience. Because it has omega-6 added to the preparation, I have been avoiding it.  I can't imagine why they do it. Also, the astaxanthin added makes the capsule appear orange, making it difficult to judge its oxidative status.

  • Anonymous

    2/2/2010 12:00:10 AM |

    The good doctor here gives lots of free advice that runs counter to the big bucks pockets of the drug and insurance industry. So far his advice hasn't failed me yet. My lipid profiles have greatly improved since I started reading this blog. If Dr. Davis wants to partner up with a premium brand of omega-3 then that is OK by me. Nothing comes free and this is one way we can all say thank you and support this blog.

  • Ateronon

    2/2/2010 4:39:56 AM |

    http://online.wsj.com/article/SB10001424052748704107204575039590838522222.html

    Is there anything fish oil can't do?

    How about as an engine oil additive. Could prevent those gummy deposits.

    http://online.wsj.com/article/SB10001424052748704107204575039590838522222.html

  • Anonymous

    2/5/2010 9:16:27 PM |

    Wish we could get Dr Oz and Dr Davis together somehow...... see the following from the RealAge website where Dr Oz is suggesting animal fat are bad and grains are good...again

    source http://www.realage.com/tips/live-longer-with-this-protein

    "The red-meat and processed-meat eaters also had a higher risk of dying from cancer or heart disease. Why? Researchers aren't exactly sure. Could be the preservatives in processed meats. Could be the artery-clogging fats found in beef and bacon. Or it could be that both red- and processed-meat eaters consume less body-friendly foods like whole grains, fruit, and veggies. In fact, other research shows that vegetarians fare best when it comes to heart disease mortality."

    The last line is interesting.
    Trevor

  • H. Guide

    2/15/2010 8:42:25 AM |

    I often hear a general guideline that 2 servings of non-predatory fish (preferably wild caught and definitely not farm-raised) is generally accepted as safe, or at least minimally risky, and that this is likely a good guideline for everyone, but especially pregnant women and children.

  • Jenny

    3/4/2010 12:08:18 AM |

    I also take OMAPURE.  It's almost as pure as LOVAZA (70% vs. 84%) but is tested by third party IFOS and has no PCBs and mercury.  I wish OMAPURE was cheaper but it is still less than Sears Fish Oil and much much less than the rip off Lovaza!  Lovaza is such a joke - should be exposed on 60 minutes.

  • Jason

    3/9/2010 1:41:28 PM |

    This Pharmatrend Cardio Formula is ALMOST as concentrated as Lovaza.  Lovaza is about $150 for 120 capsules (a 1 month supply for a the FDA approved 4g/day dose for triglyceride reduction).  The Pharmatrend is $30 + shipping for a 15 capsule package!  That's almost a 4 day supply for triglyceride reduction.  So, it's $30 x 7.5 for a month supply.  That's $225/month!  However you slice it, it's actually less expensive to go with the prescription.  If you are covered by insurance, you will only come out of pocket at around $30-$40 per month for the FDA approved prescription.  Don't let "supplement" make you think it's better or less expensive

  • Rohit

    3/12/2010 5:19:27 PM |

    Lovaza is an ethyl ester of EPA not the actual EPA itself. It also includes DHA. However, the ester is supposed to significantly lower blood pressure and cholesterol far more than just plain old normal omega 3.

  • H. Ghr

    4/11/2010 12:35:44 PM |

    Gilles, just out of curiosity, do you consider me a “priest” of this “new religion of health data as the solution to all/most healthcare problems”? If not, what are you talking about? You read a lot more than I do but I don’t recall hearing anyone suggest that.

  • Charlotte

    5/22/2010 10:12:43 PM |

    What really upsets me is that physician only supplement companies with high quality supplements and processing standards that meet or exceed GSK's are NOT allowed to make the claim that Omega 3's helps lower triglycerides. Simply because the FDA has not evaluated their product. Really?

    The FDA is a joke. They approve unsafe drugs based on studies given to them from drug companies. Since the FDA does not require them to provide all of their research, drug companies are allowed to show them their studies that had positive results with little side effects, leaving out the incriminating studies. Some drugs are "fast tracked" through the approval process are then later pulled from the market due to a high number of deaths and side effects. If you think that the FDA protects us...think again.

    Also note, that a majority of studies are only done on men. Women are excluded due to the risk of pregnancy and drugs are NOT tested on pregnant women in a lab. They use animals for this. While we are biologically similar to rats, we are NOT the same. But nevertheless there are many "approved" drugs that are deemed safe for pregnant women and are only restricted later after clinical usage has shown to cause birth defects.

    When a drug is removed from the market everyone is upset at the drug companies. I say, stop blaming the drug companies for being what they are and are expected to be. How about we start blaming the FDA?! Let's hold them accountable for their actions. Suing the drug companies it ineffective. No, they don't want to lose money but let's face it...they don't won't go bankrupt and often settle. People need to wake up...just because something is FDA approved, does NOT make it safe!

    Sorry to rant...but this really irks me.

  • E Xtenze

    6/13/2010 5:58:03 AM |

    Yes, i agree fish are high protein, but for the fish oil supplement, we should have to take care about the quality and contamination.

  • fish oil

    6/22/2010 6:09:47 AM |

    After read this post I think that fish oil is better to take as supplement because as I think that fish oil is more beneficial and also good for health. It is also gives prevention against many of decease.

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  • Todd

    9/9/2010 1:50:30 AM |

    You guys are all missing the point entirely. As can easily be seen from the commercial, Lovaza is manufactured in the future from a lab at the bottom of the ocean.  It requires a prescription because it must be shipped from the future to the present, which you can imagine is quite expensive (and dangerous).  The FDA regulates this process of transporting the drug through time.  The dietary supplement formulations of fish oil are actually smuggled through the time rift by rebels similar to those depicted in the Mad Max movies, starring Mel Gibson, thus explaining their cheaper price tag.

  • safe supplements

    9/30/2010 8:36:34 AM |

    Fish oil supplements and liquid fish oil have been suggested by doctors for lowering triglyceride levels, but people who are allergic to fish should not take fish oil supplements.

  • TedHutchinson

    9/30/2010 10:19:43 AM |

    @ safe supplements
    I used to be allergic to fish.
    I couldn't eat fish 2 days running because if I did I'd have a severe sore throat.
    I found raising my anti-inflammatory status with omega 3, vitamin d and magnesium has eliminated my tendency to get allergic reactions to fish or anything else. So now I don't get hay fever either. It's now been some years since I last used an anti histamine.
    Some fish allergic people may find Krill oil is less likely to cause a reaction but be aware some Krill oil capsules also contain fish oil.
    There are also omega 3 formulations from algal-docosahexaenoic acid: effects on triglyceride levels and other cardiovascular risk factors. that you may want to consider but they are a lot more expensive when considering the amounts required to be effective.

  • Micheala Woods

    10/22/2010 6:56:00 PM |

    Fish oil without doubt is highly beneficial, make sure you take the purest form available in the market.

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  • Anonymous

    11/19/2010 2:35:25 PM |

    for years the fish oil products that we bought in vitamins stores contained a statement that " The FDA has not evaluated these statments". all of a sudden lovaza comes on the scene & its nowe okay. they say lovaza is purified. This raises the question that the FDA either is lying to us now or they were letting us be pisioned before. which one is it? the FDA in the most corrupt agency of the federal government. ask yourself this question. did you ever hear of restless leg syndrome until the FDA approve a prescription medication for it? if the drug companies pay the right people they can get anything approved.

  • fish oil supplements

    12/1/2010 2:24:21 AM |

    I have been using fish oil supplements for years and so far I am very satisfied on its performance. Lovaza is very new to me. I am still looking for more info about it. This article will help he clarify everything.

  • Anonymous

    12/6/2010 7:56:55 PM |

    I take EPA Xtra from Nordic Naturals

    Two Serving:

    EPA 1060 mg
    DHA 274 mg

    Cost Less than $30 per 60 capsule bottle. Just do your own research on quality and efficacy.

  • Anonymous

    12/15/2010 4:13:24 AM |

    Lots of info to take in....I see the pros and cons written before me. but just tell me this!

    "i could buy purity products sealogix pharmacuetical grade fish oil ---- 1.8g EPA & .9g DHA per teaspoon.

    or..........

    Loveza comes in at 1.8g EPA and 1.5g DHA per 4, 1 gram capsules

    which one?

  • Vegetarian supplements

    12/22/2010 1:26:55 AM |

    Fish oil is also a healthy alternative apart from the usual vitamins being used.

  • grace058

    1/25/2011 10:47:48 AM |

    fish oil supplements for me. It's proven to our family because of its very rich benefits gives to our health condition such as Eases Depression, Lowers Cholesterol, Eliminates Joint Pain and so much more!

  • Amy Wike

    1/27/2011 5:28:20 AM |

    I definitely believe in the benefits of fish oil supplements.

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  • Anonymous

    3/15/2011 8:20:18 PM |

    I dont know why everyone thinks lovaza is a rip off.  My prescription plan covers it and I pay less than $10 per/month and despite what some people on here have been saying, nothing, NOTHING, has anywhere near the EPA/DHA as lovaza....almost 3600MG daily dose

  • Anonymous

    3/30/2011 1:13:47 AM |

    Hi everyone
               I started on Lovaza about a month ago, my doctor feeling this is a last resort to lowering my triglycerides as all other meds left me with with severe muscle soreness when using them. I've been reading as far back as I can go on this particular subject w/ using Lovaza and I'm confused. I have a couple of questions...1, is Lovaza a safe product with as much natural ingredient as possible? 2, or is it an artificial made product?

  • Swacher

    5/14/2011 3:20:35 PM |

    GSK made the financial investment to have the studies done.  What's stopping the supplement companies?  To answer your question, yes I did hear of retless leg syndrome before the FDA approved a prescription medicine for it.  I understand people's frustration with big pharma and the FDA and if you dislike them you are free not to utilize any FDA approved pharmaceuticals.

  • Angelo

    5/15/2011 12:16:30 AM |

    What a way to sell your supplements. Your a good hustler Doctor.

  • Angelo

    5/15/2011 12:18:52 AM |

    You haven't researched very much then. And it's not 3600 per 4 pill dose it's 3,360. Big difference.

  • Angelo

    5/15/2011 12:23:16 AM |

    Your an idiot if you need to ask "what's stopping the supplement companies from making the financial investment to have studies done. What supplement company has the money a pharm company has. Do you have any idea what a good study cost? I guess not.

  • Angelo

    5/15/2011 12:25:22 AM |

    Dude, stop reading the Health Ranger and Mercola. when you get cancer you'll be begging the Pharm company for there FDA approved drugs.

  • kansas mom

    6/17/2011 2:22:56 AM |

    Hey Doc.,
    Ok I have a question Doc. what fish oil brand do YOU say we should take? I got on here just to see what the diff. was between the two because our doc. said we should take Lovaza. I find it a little interesting that she said to take it along with our reg fish oil we've been taking...

  • Minnie

    8/18/2011 4:38:39 AM |

    I have 280 triglycerides I was prescribed Lovaza, but  my insurance denied it, my doctor told me to take  over the counter fish oil. I am undecided and confused I need help. Which brand and its purity etc

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