Heart Scans: An Interview with Jimmy Moore

My friend, Jimmy Moore, of The Livin' La Vida Low Carb Show, posted this video of an interview I did with him.

I provide some background on how heart scanning came about and how it led to the creation of the Track Your Plaque program.

It reminds me how far we've come over the 8 years since the program got started. From its modest start as just an information resource to help people understand their heart scan score, to a comprehensive program that helps followers gain incredible control over coronary plaque and coronary risk that has now expanded to over 30 countries. High-tech heart procedures still dominate public consciousness, but the tremendous power of real heart disease prevention efforts are gaining more and more attention as each day passes.

Comments (2) -

  • Might-o'chondri-AL

    9/11/2011 1:00:42 AM |

    Pardon me,     Server error makes me post here ....
    Colon cancer runs in my family & 1st cousin succumbed in his early 40s; USA colon cancer affects +/- 2% of men and +/-1.5% women aged 50 - 70, with higher rates among African-americans. Cancer pathology does not follow lineal constructs, so I will be generalizing (again); colon cancer can be hereditary non-polyposis, familial adenomatous polyposis (polyps), flat adenoma or sporadic colorectal cancer.

    Dietary fiber provides the environment for intestinal bacteria to make butyrate for us; and butyrate is beneficial when it produces hydrogen sulfide (H2S). In the large intestine (colon) epithelial cells this butyrate H2S induces a proton "leak" in that cell's mitochondrial electron transfer chain (that cell uses & needs  less oxygen); this uncoupling slows that cell's cycle so that there is less cell division, and simultaneously depresses cytochrome c oxidase 1 & 2 enzymes which prevents that mitochondria from signalling for apoptosis (death). The boost in colonocyte (cellular) H2S also raises that cell's level of the anti-oxidant glutathione; and fosters other beneficial mitochondrial  processes by opening the mitochondrial membrane's K-ATP channel.

    Dietary derived H2S comes from sulfurous protein (ie: amino acids methionine, taurine, cysteine & cystine) metabolized by intestinal bacteria;  and more significantly this type of  dietary induced load of H2S depresses the beta-oxidation of butyrate in colonocytes. When it comes to the sexes it is women who more readily produce H2S from sulfurous protein, yet men will produce a higher total amount of H2S; which may indicate why both sexes have similar colon cancer rates.

    Sulphur rich cruciferous vegetables (broccoli, cauliflower, brussel sprouts, cabbage & kale) are not high in sulfurous proteins;  metabolism of their sulphur favors a bit more sulphur uptake into local colon tissue than bacterial H2S pathways. Think of the slow steady butyrate H2S output in colonocytes as a pre-treatment; this pre-conditioning is hormetic (hormesis is how a little bit of something potentially dangerous, like H2S, can be good for you that some might phrase as "what doesn't kill you makes you stronger").


    Cancer of the colon unfortunately can side-step the preventative action of butyrate H2S when one of the enzymes (cystathine Beta-synthase) butyrate uses to generate H2S gets knocked out. How or why this happens in an individual is not dealt with here; the point is that a certain level of reliable H2S from butyrate will hold down the viabilty of colon cancer cells. Once the colon cancer cell has shifted  it's pheno-type from epithelial pheno-type to mesencymal pheno-type the same cellular protective effects of H2S (see 2nd paragraph above) will then unfortunately help that cancer cell avoid dying (apoptosis).

    In a petri dish H2S will kill some colon cancer cell lines; this works because those cancers are not interfacing with the colon's bacterial dynamic. The "nooks and crannys" of the intestinal crypts have 2 distinct mucus (mucin) made up from long chain carbohydrates (oligo-saccharides); the sialo-mucin is more to the surface and usually deals with microbes, while the sulfo-mucins are in the lower depths of the crypts. We individuals have different antigens that affect the rate at which we degrade the sialo-mucin; furthermore, there is a drop in the number of sialo-mucins when the transformation of colo-rectal cancer occurs. It should be noted that the density of sialo-mucin and sulfo-mucin has differences all along the length of the colon and rectum, with nuances related to gender and can shift their ratios at a site.

    There are specific colon bacteria which utilize the sulfate they get from sulfo-mucin; sulfate reducing bacteria use it for their own "respiration" and put out H2S. Yet "normally" sulfate reducing bacteria  are apparently not mostly using the sulfate we add to the colon from our food (this may be because certain  sulfur bacteria varieties, like "normal" desulfovibrio, have a cellular program to interact readily with an oligo-saccharide property of sulfo-mucin in order to take up that sulfate). When there is a shift to depleted sialo-mucin and extra ordinary sulfo-mucin the colon sulfur bacteria population varieties also alters; and certain sulfate reducing bacterial varieties become enriched at the expense of other bacteria.

    At which time the colon levels of  bacterial produced H2S can rise and, just like high dietary spin off H2S; this then will depress butyrate's output of H2S  in colonocytes (where any incipient colon cancer's epithelial pheno-type needs to be held in limbo). The natural anti-cancer slow release of H2S from butyrate is then an altered state of high level of H2S in the colon;  with not enough sialo-mucin in the upper portions of colon crypts epithelial cells deeper in the crypt are more vulnerable .

    Furthermore, with the shift toward excessive sulfate reducing bacteria (ex: desulfobacter, desulfobolbus and desulfotomaculum as opposed to  "normal" desulfovibrio) , there is the possibility that some cancer cell lines will use that bacterial supplied H2S to more readily morph into their mesenchymal pheno-type. This would be due to H2S impairing certain coloncyte cell line's DNA repair so that there is then damage to the original genome. For details see Mol Cancer Res 2006;4(1):9-14 "Evidence that H2S is a Genotoxic Agent"  complete text at http://
    mcr.aacrjournals.org/content/4/1/9.full

  • Might-o'chondri-AL

    9/12/2011 6:45:10 AM |

    To Greensleeves  (Server blocking where belongs),
    You might enjoy this all sourdough rye study "Structural diff. btwn. Rye & wheat ...lower post-prandial insulin ..." in 2003 Am J Clin Nutri; 78(5):957-964 full text http://www.ajcn.org/content/78/5/957.full

    And 2009 "Endosperm & whole grain rye breads ... beneficial blood glucose profile" in Nutrition Journal 2009, 8:42 full text http://www.biomedcentral.com/content/pdf/1475-2891-8-42.pdf

Loading
Test your own thyroid

Test your own thyroid

134 people responded to the latest Heart Scan Blog poll:


When I ask my doctor to test my thyroid, he/she:

Accommodates me without question 45 (33%)

Questions why, but orders the tests 49 (36%)

Refuses because you seem "healthy" 20 (14%)

Refuses without explanation 4 (2%)

Ridicules your request 16 (11%)



That's better than I anticipated: 69% of physicians complied with this small request. After all, you're not asking for major surgery. You're just asking for a very basic test, as basic as a blood count or electrolytes. 36% of respondents said that their doctor asked why, but still complied; this is simply practicing good medicine--If there is a problem, your doctor would like to know about it.

However, the remainder--31%--were refused in one way or another. Incredibly, 11% were ridiculed.

Although this was not asked in the poll, I believe that it is a safe assumption that you asked with good reason: you're abnormally fatigued, you have been gaining weight for no apparent reason or can't lose weight despite substantial effort, or you feel cold at inappropriate times.

Let's say you're tired. Ever since last summer, you've suffered a gradual decline in energy.

So you ask your doctor to assess your thyroid. He refuses. "You're just fine! There's nothing wrong with you."

You disagree. In fact, you are quite convinced that there is something physically wrong. What do you do?

You could:

--Drink more coffee
--Exercise more in the hopes that it will snap you out of your lethargy
--Sleep more
--Take stimulants of various sorts

Or, you could get your thyroid assessed and settle the issue. But how can you get this done when your doctor won't accommodate you, even though you have perfectly fine health insurance and are simply interested in feeling better and preserving your health?

You could test your thyroid yourself. This is why we're making self-testing kits available. Test kits are available here.

This is yet another facet of the powerful revolution that is emerging: Self-directed health.

Comments (15) -

  • Tom

    9/7/2009 2:47:55 PM |

    In addition to home kits we might create drop in health shops where healthy people are given a quick set of automated tests/scans and the results made available to them online.

  • Lincolnb

    9/7/2009 3:26:27 PM |

    This is a great tool as many of my clients mention their thyroids and wonder if there was a way to monitor it.  When will this be available in the UK?

  • Anna

    9/7/2009 4:11:56 PM |

    I'm not sure getting tested is as big of an issue as getting a proper diagnosis and treatment.  I know lots of women who have their their thyroids tested (at least minimally with a TSH) but the results are not properly interpreted or treated.   Usually they end up with anti-depressant meds or are told to eat less and exercise more (or both).

    My thyroid was tested for about ten years (mostly with just the TSH and total T4, not the full complement of thyroid tests) for more than ten years because of two infertility investigations and later, symptoms of fatigue, etc.  I didn't ask for these tests; they were routine as part of a panel or the doctor specified them.  

    My HMO network doctors failed to see that my TSH was slowly slowly rising in that decade because they only looked at the recent result and not the trend (and there was a faster rate of increase after 7-8 years of testing).  They also missed that my results  were always in the "upper end" of the reference range (in late 2002 at least two national medical boards said the upper range was suspicious of development of mild hypothyroidism and the range should be adjusted downward).  Last year when I brought these AACE and NACL recommendations to the attention of the local HMO network lab supervisor, he was unaware of of the new range recommendations and promised to look into it.  I was pleased to note the ref range was somewhat adjusted down a few months later.

    So for me, the lab tests were less an issue; I had numerous TSH and total T4 tests while my symptoms progressively increased, but with little good.  

    The biggest difficulty was getting a correct diagnosis and the proper treatment, instead of attempts to suppress symptoms with other meds (I felt in my gut this was the wrong approach and I mostly resisted it).  

    The best treatment I've tried to date has been desiccated thyroid hormone (I'm now taking 1 grain of Nature-throid daily); to get to this it took a full three years with a continual search to find a local doctor who would use and correctly interpret the right lab tests *and* take into account my symptoms.   I hear similar stories from other hypothyroid people.

  • Dr. William Davis

    9/7/2009 8:43:28 PM |

    Yes, absolutely correct, Anna. Getting tested is just the first step.

    Once tested, understanding what they mean is the next step. But at least you know where you start. It's certainly better than not having any data at all.

    Next hurdle: Getting treatment when you need it. A topic for future discussion!

    Lincolb--It is available in the U.K. by ordering.

  • Daddy

    9/7/2009 10:02:24 PM |

    I guess that's how CA and NY can justify putting restrictions on their sale.  Sheesh!  Reminds me of when CA was on the brink of criminalizing home-schooling.

  • Hot Cover Girls Central

    9/8/2009 1:28:17 AM |

    That's great! I will recommend that to my sister and friend who were always complaining that they might have thyroid problem.
    See yah!

    Cathy Young
    http://fashionhotcelebs.blogspot.com/

  • pooklaroux

    9/8/2009 3:18:20 PM |

    I have also been able to get my doctors to do TSH tests, but since my labs ate at the upper end of normal, they also pooh pooh my suggestion  that treating the thyroid might positively impact other issues they care about, like my cholesterol levels and my asthma.  But they would rather give me statins (which I refuse to take) and advair (which I take only because I have to be able to function.)  I think they have it in my notes that I am hypochondriac and uncompliant. So much for being proactive for my own health care! Now they think I am a nutcase!

  • Laura in Arizona

    9/8/2009 3:38:35 PM |

    I agree with Anna. My doc has routinely tested TSH for years. This past check up I told her I wanted more info on the thryoid because of my lack of energy and other symptoms. She ordered T3 and T4 along with TSH but nothing else. My TSH came in at 4.5 on a scale going to 4.5 which is a full point jump since my last test. My T3 is almost abnormal on the low end. However since they are within the lab's normal range, she says I am fine. I am making an appointment with doc #2 in my search for someone that knows what they are doing. I sure hope it does not take the 3 years to find him/her it took Anna!

  • Anna

    9/8/2009 4:06:54 PM |

    Laura,

    I'd also like to add that much of that 3 years looking for better care was also spent educating myself (I must have read every book available on hypothyroidism to get a sense of all the perspectives), so developed a sense of when to seek out another doctor's care and when to settle for "good enough for now".  

    For me, the hardest part was early on -  summoning the inner strength to get over my reluctance to find new care and thyroid hormone options.  I was acutely aware that my tactic might be viewed as "doctor-shopping" or hypochondria.   Each step wasn't always very far forward, but it was still progress in some way and far more therapeutic than stagnating (it didn't always feel like progress at the time, though).

    Good luck in your quest for better care and more thorough assessment of your thyroid function.  Be sure to get tested for anti-thyroid antibodies.

  • Anonymous

    9/8/2009 4:39:45 PM |

    Regular Doctors are always a crap shoot. If you don't mind switching Doctors, it is better to seek out a Doctor that you know will probably be receptive to alternative therapies right from the get go. Life Extension has a list of "Innovative Doctors" here:

    http://www.lef.org/Health-Wellness/InnovativeDoctors/

    Another good source for Doctors that would probably be receptive to taking a patients thyroid concerns more seriously can be found at the A4M site:

    http://www.worldhealth.net/pages/directory

    Likewise, if lipid disorders are your concern, you can find a Lipidologist at the following site:

    http://www.learnyourlipids.com/resources.php

    Hope this helps.

    John M.

  • kris

    9/8/2009 8:13:44 PM |

    here is the site to find thyroid hormones friendly doctors.
    http://www.armourthyroid.com/con_phLocator.aspx

    Dr Davis, I don't think that you are on there? LOL

  • Dennis Mangan

    9/9/2009 4:10:23 PM |

    Another option when faced with uncooperative doctors: order thyroid from an overseas pharmacy.

  • Anonymous

    9/19/2009 5:22:14 PM |

    You forgot the option of saying you look Healthy so the test is unnecessary and Ridiculing you -- but finally ordering the tests, because you wouldn't leave the room till he patronizingly agreed (hey, whatever works)... and it turns out I have multi-nodule goiter!!

  • Anonymous

    1/2/2010 10:25:33 PM |

    Your blog keeps getting better and better! Your older articles are not as good as newer ones you have a lot more creativity and originality now keep it up!

  • buy jeans

    11/3/2010 2:31:15 PM |

    Although this was not asked in the poll, I believe that it is a safe assumption that you asked with good reason: you're abnormally fatigued, you have been gaining weight for no apparent reason or can't lose weight despite substantial effort, or you feel cold at inappropriate times.

Loading